MULTICENTER NETWORK IN MATERNAL-FETAL MEDICINE

母胎医学中的多中心网络

基本信息

批准号：
3552358
负责人：
MORTIMER G. ROSEN
金额：
$ 4.61万
依托单位：
COLUMBIA UNIV NEW YORK MORNINGSIDE
依托单位国家：
美国
项目类别：
财政年份：
1986
资助国家：
美国
起止时间：
1986-04-01 至 1990-11-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/3552358
关键词：
beta adrenergic agent birth injury brain injury cerebral hemorrhage cesarean section disease /disorder prevention /control disease /disorder proneness /risk early diagnosis embryo /fetus monitoring health care service evaluation health education human morbidity human subject infant mortality labor complications monitoring device mother /infant health care perinatal pregnancy disorder chemotherapy premature infant human restricted physical activity self care ultrasonography

beta adrenergic agent birth injury brain injury cerebral hemorrhage cesarean section disease /disorder prevention /control disease /disorder proneness /risk early diagnosis embryo /fetus monitoring health care service evaluation health education human morbidity human subject infant mortality labor complications monitoring device mother /infant health care perinatal pregnancy disorder chemotherapy premature infant human restricted physical activity self care ultrasonography

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项目摘要

The multicenter concept for establishing a network of maternal-fetal medicine units is a unique opportunity to conduct clinical trials involving patient care systems. By establishing programs in several large units, answers to questions may be obtained efficiently, within short time periods, and at minimum expense since duplication of efforts in uncoordinated smaller studies can be eliminated. The Columbia University application documents a large patient population, with an established data collection system incorporating obstetrical and neonatal centers of excellence and with depth of research in endocrinology, epidemiology, infant development and nurse midwifery. Two examples of research protocols have been submitted. In the first the treatment of the very low birthweight fetus and the prevention of intraventricular and cerebral hemorrhage is pursued. In the second protocol a system designed to prevent the onset of premature birth is modeled. Both are considered of interest and meet the specific guidelines for the collaborative project.

建立孕产妇网络的多中心概念医学单位是进行临床试验的独特机会患者护理系统。通过在几个大型单元中建立程序，可以在短时间内有效地获得问题的答案时期，最低费用以来可以消除不协调的较小研究。哥伦比亚大学申请记录了大量的患者人群，并拥有已建立的数据收集系统，结合了产科和新生儿中心卓越和内分泌学，流行病学研究深度，婴儿发展和护士助产士。研究方案的两个例子已提交。首先，非常低的处理出生体重胎儿以及预防脑室内和脑的预防追捕出血。在第二个协议中，一个旨在防止的系统早产的开始是建模的。两者都被认为是感兴趣的并符合协作项目的具体准则。