PRESERVING 3-D STRUCTURE USING A BALZERS 400T

使用 BALZERS 400T 保留 3D 结构

• 批准号: 3520101
• 负责人: John H Hartwig
• 金额: $ 10.1万
• 依托单位: MASSACHUSETTS GENERAL HOSPITAL
• 依托单位国家: 美国
• 财政年份: 1988
• 资助国家: 美国
• 起止时间: 1988-02-29 至 1989-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3520101
• 关键词: biomedical equipment purchase; cell biology; cell membrane; cytoskeleton; freeze etching; lyophilization; membrane structure; biomedical equipment purchase; cell biology; cell membrane; cytoskeleton; freeze etching; lyophilization; membrane structure

Ultrasonic, electronic, and mechanical instrumentation is to be obtained to update the existing field measurement and calibra- tion facilities and to introduce a semi-automated capability to measure repeated short pulse and transient pulse ultrasound fields. The existing instruments were designed and fabricated more than 30 years ago and are now in need of updating in order to assure that accurate and reliable usage continues and that the Laboratory has the capability to deal with the types of measurements that current investigations require. The instrumentation is absolutely essential for calibrating the output of acoustic emission devices (transducers) for the exposure of animal systems involved in the study of mechanisms of interaction, immunological response, dosimetry, and for the purpose of measuring ultrasonic propagation properties of biological media. Further, the proposed updating will make available the capability of greatly expanding the scope of the work undertaken by the investigators dealing with different biomedical ultrasonic topics, by allowing for accurate measurements of short pulse exposures to be carried out, and thereby providing armamentaria to the temporal domain of clinical diagnostic ultra sound.

超声波，电子和机械仪器是 获得以更新现有的现场测量和CALIBRA- 设施并引入半自动化功能 测量重复的短脉冲和瞬态脉冲超声 字段。 现有的仪器的设计和制造更多 比30年前，现在需要更新 确保准确可靠的用法继续存在，并且 实验室有能力处理 当前调查需要的测量。 这 仪器对于校准绝对必要 声发射设备的输出（传感器） 涉及机制研究的动物系统的暴露 相互作用，免疫反应，剂量法，以及 测量超声传播特性的目的 生物媒体。 此外，拟议的更新将使 可用的功能大大扩展了范围 调查人员处理不同的工作 生物医学超声主题，通过允许进行准确的测量 要进行的短脉冲暴露，从而提供 临床诊断Ultra的时间领域的Armamentaria 声音。