COMPUTER COMMUNICATIONS FOR PSYCHIATRIC RESEARCH/THERAPY

用于精神病学研究/治疗的计算机通信

• 批准号: 3508932
• 负责人: DOUGLAS HOLMES
• 金额: $ 6万
• 依托单位: DMH ASSOCIATES, INC.
• 依托单位国家: 美国
• 财政年份: 1988
• 资助国家: 美国
• 起止时间: 1988-05-01 至 1990-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3508932
• 关键词: bipolar depression manic phase; blood chemistry; clinical depression; computer assisted patient care; drug adverse effect; human subject; major depression; medical appointment; mental disorder chemotherapy; mental health information system; telecommunications; therapy compliance

This Phase-II proposal builds on the work of Phase I, together with interim work funded by the New York State Science and Technology Foundation, in further developing and strengthening a computer system aimed at (a) providing information about psychopharma- cologicals, (b) providing regularly scheduled reinforcement and monitoring of drug compliance, (c) collecting self-report side effects data, (d) providing illness severity information to therapists about patients with affective disorders. The second aim of the project is to evaluate, using a quasi-experimental design, specified outcomes associated with use of the system (blood serum levels, pill counts, morbid events, patient & therapist satisfaction). Clinic psychiatric outpatients with one of the DSM- III diagnoses (major depression, bipolar disorder:manic, dysthymia) and who are beginning a psychopharmacological drug regimen will be randomly assigned to experimental (computer intervention) or to control groups (one placebo, one no placebo). Patients will be assessed on a number of factors (possible covariates) in addition to outcomes as a means to examining interrelationships among factors predicting compliance and side effect outcomes. The experimental design hypotheses will be tested using logistic regression and other analytic techniques. The system being developed and field tested is intended for use in clinics or in private practice groups as an adjunct to existing therapies involving medication regimens.

该阶段II提案以第一阶段的工作为基础 纽约州科学技术资助的临时工作 基础，进一步开发和加强计算机 针对（a）提供有关心理药物的信息的系统 - （b）提供定期安排的加固和 监测药物合规性，（c）收集自我报告方面 影响数据，（d）提供疾病严重性信息 关于情感障碍患者的治疗师。 第二个目标 该项目的内容是使用准实验设计评估 与使用系统相关的指定结果（血清 水平，药丸计数，病态事件，患者和治疗师 满意）。 DSM-诊所精神病院门诊病人之一 III诊断（重度抑郁症，躁郁症：躁狂，心律失常） 谁开始心理药物药物方案 随机分配给实验（计算机干预）或 对照组（一个安慰剂，一个没有安慰剂）。 患者会 对许多因素（可能的协变量）进行了评估。 结果作为研究之间的相互关系的一种手段 预测合规性和副作用结果的因素。 这 实验设计假设将使用逻辑进行检验 回归和其他分析技术。 开发和现场测试的系统旨在用于 诊所或私人执业小组作为现有的辅助 涉及药物方案的疗法。