Integrating cAMP- and nitric oxide- signalling in Mycobacterium tuberculosis: novel regulatory networks that challenge established paradigms

在结核分枝杆菌中整合 cAMP 和一氧化氮信号传导：挑战既定范例的新型调控网络

• 批准号: BB/K000330/1
• 负责人: Galina Mukamolova
• 金额: $ 40.25万
• 依托单位: University of Leicester
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2013
• 资助国家: 英国
• 起止时间: 2013 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=BB%2FK000330%2F1
• 关键词: Integrating; cAMP; nitric; oxide; signalling

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

GTR目前尚未用于所有资助研究的摘要。这通常是因为提交提案时不需要摘要，但可能是因为它包含了敏感信息，例如个人详细信息。

项目成果

Efficient Protein Digestion at Elevated Temperature in the Presence of Sodium Dodecyl Sulfate and Calcium Ions for Membrane Proteomics.

在十二烷基硫酸钠和钙离子存在下，在高温下高效消化蛋白质，用于膜蛋白质组学。

• DOI: 10.1021/acs.analchem.9b00484
• 发表时间: 2019
• 期刊: Analytical chemistry
• 影响因子: 7.4
• 作者: Loraine J

A Persistent Tuberculosis Outbreak in the UK Is Characterized by Hydrophobic fadB4-Deficient Mycobacterium tuberculosis That Replicates Rapidly in Macrophages.

• DOI: 10.1128/mbio.02656-22
• 发表时间: 2022-12-20
• 期刊: mBio
• 影响因子: 6.4
• 作者: Farzand R;Haigh RD;Monk P;Haldar P;Patel H;Pareek M;Verma R;Barer MR;Woltmann G;Ahyow L;Jagatia H;Decker J;Mukamolova GV;Cooper AM;Garton NJ;O'Hare HM
• 通讯作者: O'Hare HM

Protein kinase B controls Mycobacterium tuberculosis growth via phosphorylation of the global transcriptional regulator Lsr2

蛋白激酶 B 通过全局转录调节因子 Lsr2 的磷酸化来控制结核分枝杆菌的生长

• DOI: 10.1101/571406
• 发表时间: 2019
• 作者: Alqaseer K

Exposure to nitric oxide drives transition to differential culturability in Mycobacterium tuberculosis

• DOI: 10.1101/2021.09.28.462152
• 发表时间: 2023-11-07
• 期刊: bioRxiv
• 作者: Glenn，Sarah M;Gap-Gaupool，Brindha;Mukamolova，Galina V
• 通讯作者: Mukamolova，Galina V

Development of an In Vitro Assay for Detection of Drug-Induced Resuscitation-Promoting-Factor-Dependent Mycobacteria.

• DOI: 10.1128/aac.00518-16
• 发表时间: 2016-10
• 期刊: Antimicrobial agents and chemotherapy
• 影响因子: 4.9
• 作者: Loraine J;Pu F;Turapov O;Mukamolova GV
• 通讯作者: Mukamolova GV