ECHOCARDIOGRAPHIC RISK ASSESSMENT--CHEST PAIN PATIENTS

超声心动图风险评估——胸痛患者

• 批准号: 2734912
• 负责人: KIRSTEN E FLEISCHMANN
• 金额: $ 8.8万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 1994
• 资助国家: 美国
• 起止时间: 1994-07-01 至 1999-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2734912
• 关键词: angina pectoris; coronary intensive care; disease /disorder proneness /risk; echocardiography; electrocardiography; health care cost /financing; health care policy; heart surgery; hospital length of stay; hospital utilization; human subject; magnetic resonance imaging; medical complication; mitral valve; noninvasive diagnosis; outcomes research; pain; preoperative state; prognosis; statistics /biometry

Recent trends including development of new diagnostic and therapeutic modalities and increasing pressure to provide cost-effective care have made risk stratification and technology assessment increasingly important in cardiovascular research. This will be achieved through a series of studies exploring the utility of echocardiography in the risk stratification of patients with chest pain. We hypothesize that routinely available qualitative data from the echocardiogram can be used to risk stratify patients and that such data provide information above and beyond clinical data. Thus, by means of a prospective cohort study, we will: 1) Investigate the correlation between echocardiographic variables and the risk of a. complications during hospitalization; and b. long-term prognosis and functional status. 2) Determine whether echocardiographic variables add incremental risk stratification information after consideration of clinical and electrocardiographic data. 3) Develop and validate prospectively a predictive algorithm based on clinical, electrocardiographic and echocardiographic variables. 4) Assess the cost-effectiveness of performance of routine echocardiography in subsets of patients admitted for acute chest pain. In the latter part of the research program, these methodologies for technologies for technology assessment will be used to evaluate the role of cardiac imaging in other settings such as identification of preoperative predictors of outcome in patients undergoing mitral valve repair and replacement or assessment of aortic regurgitation with magnetic resonance imaging. This research should prove useful to both clinician and health policy maker.

最近的趋势，包括开发新的诊断和治疗性 方式和提供具有成本效益的护理的压力增加已有 使风险分层和技术评估越来越重要 在心血管研究中。 这将通过一系列探索实用程序来实现 胸部患者风险分层的超声心动图 疼痛。 我们假设从 超声心动图可用于使患者分层的风险，并且此类数据 提供超出临床数据的信息。 因此，通过 一项前瞻性队列研究，我们将： 1）研究超声心动图变量与 a的风险。住院期间的并发症；和b。长期 预后和功能状态。 2）确定超声心动图变量是否增加了增量风险 考虑临床和 心电图数据。 3）基于 临床，心电图和超声心动图变量。 4）评估常规表现的成本效益 急性胸痛的患者子集的超声心动图。 在研究计划的后期，这些方法论 技术评估技术将用于评估角色 在其他设置中的心脏成像，例如识别 术前预测二尖瓣的患者 维修和置换或评估主动脉反流 磁共振成像。 这项研究应该证明对两者都有用 临床医生和卫生政策制定者。

项目成果

Weekend and holiday exercise testing in patients with chest pain.

周末和节假日对胸痛患者进行运动测试。

• DOI: 10.1046/j.1525-1497.1999.00274.x
• 发表时间: 1999
• 期刊: Journal of general internal medicine
• 影响因子: 5.7
• 作者: Krasuski,RA;Hartley,LH;Lee,TH;Polanczyk,CA;Fleischmann,KE
• 通讯作者: Fleischmann,KE

Noninvasive imaging for the diagnosis of coronary artery disease: focusing the development of new diagnostic technology.

冠状动脉疾病诊断的无创成像：重点发展新诊断技术。

• DOI: 10.7326/0003-4819-131-9-199911020-00008
• 发表时间: 1999
• 期刊: Annals of internal medicine
• 影响因子: 39.2
• 作者: Hunink,MG;Kuntz,KM;Fleischmann,KE;Brady,TJ
• 通讯作者: Brady,TJ

Effect of diabetes mellitus on the presentation and triage of patients with acute chest pain without known coronary artery disease.

糖尿病对无已知冠状动脉疾病的急性胸痛患者的表现和分类的影响。

• DOI: 10.1016/s0002-9343(98)00327-1
• 发表时间: 1998
• 期刊: The American journal of medicine
• 作者: Lopez-Jimenez,F;Goldman,L;Johnson,PA;Polanczyk,CA;Cook,EF;Fleischmann,KE;Orav,EJ;Lee,TH
• 通讯作者: Lee,TH