P6: SHARED CORE FACILITIES: BIOMOLEC COMPUT & GRAPHICS: CELL CULT: DNA SEQ & SYN

P6：共享核心设施：生物分子计算

• 批准号: 6121487
• 负责人: GARY QUIGLEY
• 金额: $ 23.09万
• 依托单位: HUNTER COLLEGE
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-09-30 至 1999-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6121487
• 关键词: biotechnology; building /facility design /renovation; computers; genetics; genome; minority institution research support; nuclear magnetic resonance spectroscopy; structural biology; technology /technique; biotechnology; building /facility design /renovation; computers; genetics; genome; minority institution research support; nuclear magnetic resonance spectroscopy; structural biology; technology /technique

The functions/facilities are these: Biomolecular computation and Graphics - for structural modeling of nucleic acids, proteins, and ligands. Biopreparations - for culture media, bulk microbial cells, plasmid or phage libraries, and "biosensor" studies. Cell Culture - for mammalian cell production. Network - to allow RCMI scientists to access relevant databases and communicate as needed. Nuclear Magnetic Resonance - for molecular structure determination and verification. Sequencing, Synthesis and Separations - synthesis of DNA oligonucleotides and of peptides, peptide sequencing, and analysis of purity. X-ray Diffraction - confirmation of molecular structures and fundamental studies of macromolecular conformations.

功能/设施是： 生物分子计算和图形 - 用于结构建模 核酸，蛋白质和配体。 生物准备 - 文化 培养基，散装微生物细胞，质粒或噬菌体文库，以及 “生物传感器”研究。 细胞培养 - 用于哺乳动物细胞的产生。 网络 - 允许RCMI科学家访问相关数据库和 根据需要进行交流。 核磁共振 - 分子 结构确定和验证。 测序，合成和 分离 - DNA寡核苷酸和肽的合成， 肽测序和纯度分析。 X射线衍射 - 确认分子结构和基础研究 大分子构象。