CORTICAL REPRESENTATION OF THE VISUAL IMAGE

视觉图像的皮质表征

• 批准号: 2631650
• 负责人: MICHAEL J HAWKEN
• 金额: $ 23.51万
• 依托单位: NEW YORK UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1990
• 资助国家: 美国
• 起止时间: 1990-05-01 至 2003-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2631650
• 关键词: Macaca; behavioral /social science research tag; color visions; data collection methodology /evaluation; form /pattern perception; histology; human subject; image processing; light intensity; motion perception; neural information processing; neurons; neurophysiology; smooth pursuit eye movement; visual cortex; visual pathways; visual perception; visual stimulus; visual threshold

Our objective in this research is to uncover what role cortical neurons play in processing temporal components in a natural visual environment. We will study for V1 neurons and for pursuit eye movements how context modulates the temporal responsiveness, because temporal changes are inherent in normal vision, and visual perception of targets in the natural visual environment is always in context . 1. We will characterize the temporal properties of different classes of V1 neuron for stimulus patterns defined by flicker, motion, color or texture and ask what factors modulate the temporal tuning functions. Neurons will be classified by laminar location and grouped into functional classes. We will study the effect of luminance and color contrast on temporal tuning curves to examine the effects of stimulus contrast on contrast gain. We will compare the effects on temporal response functions of local, overlapping adaptive stimuli with remote, contextual stimuli. In separate experiments we will determine the spatio-temporal response functions of different classes of V1 neurons with stimulus patterns defined by luminance or amplitude modulated texture. 2. We aim to measure the spatio-temporal tuning of visual pursuit by accurate measurement of eye movements in human subjects. We will measure pursuit performance while presenting pursuit targets on textured backgrounds or surrounded by textured contextual stimuli. In this way we can compare the effects of adapting contrast and remote context on V1 neurons and oculomotor performance. Finally, we will study the sensitivity of pursuit eye movements to perturbations in speed, stimulus class or contrast to determine the degree of cue invariance for pursuit. This work will test fundamentally new views of primary visual cortex as an image processing area by determining to what extent elaborate V1 image processing has an effect on behavioral outcome. The significance of this work is its contribution to understanding the relation between cortical information processing and sensorimotor integration.

我们这项研究的目标是揭示皮质神经元的作用 在自然视觉环境中处理时间成分。 我们将研究 V1 神经元和追踪眼球运动的背景 调节时间响应性，因为时间变化是 正常视力所固有的，以及对目标的视觉感知 自然的视觉环境总是处于语境中的。 1. 我们会 表征不同类别 V1 神经元的时间特性 用于由闪烁、运动、颜色或纹理定义的刺激模式，以及 询问哪些因素调节时间调谐函数。 神经元会 按层流位置分类并分为功能类别。 我们将研究亮度和颜色对比度对时间的影响 调整曲线以检查刺激对比度对对比度的影响 获得。 我们将比较对时间响应函数的影响 局部的、重叠的适应性刺激与远程的、情境刺激。 在单独的实验中，我们将确定时空响应 具有刺激模式的不同类别 V1 神经元的功能 由亮度或幅度调制纹理定义。 2. 我们的目标是 通过准确测量视觉追踪的时空调节 测量人类受试者的眼球运动。 我们将衡量追求 性能，同时在纹理背景上呈现追逐目标或 周围环绕着有质感的情境刺激。 这样我们就可以比较 适应对比度和远程环境对 V1 神经元的影响 动眼神经性能。 最后我们来研究一下灵敏度 追踪眼球运动对速度、刺激类别或扰动的影响 对比来确定追踪的线索不变性程度。 这项工作将从根本上测试初级视觉皮层的新观点： 一个图像处理区域通过V1确定到什么程度 图像处理对行为结果有影响。 意义 这项工作的贡献在于它对理解之间的关系做出了贡献 皮质信息处理和感觉运动整合。