SCREENING, CHARACTERIZATION & ACQUISITION OF REAGENTS

筛选、表征

• 批准号: 2297102
• 负责人: ARMEAD H JOHNSON
• 金额: $ 6万
• 依托单位: GEORGETOWN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1988
• 资助国家: 美国
• 起止时间: 1988-07-29 至 1996-09-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2297102
• 关键词: SCREENING; CHARACTERIZATION; ACQUISITION; REAGENTS

This contract is for the continued investigation of histocompatibility antigens unique to ethnic populations in the United States, with emphasis on Blacks and Native Americans. The contractor will screen sera from multiparous women to identify and acquire reagents capable of recognizing antigens unique to these populations. Even though much work has been done in this area over the past six years through previous contracts, there are still many individuals whose HLA typings are incomplete, placing them at a disadvantage when organ transplant is required. Full identification of the antigens of the MHC will lead to better matches for these populations, improving graft survival and reducing health care costs, much of which is federally subsidized.

该合同是为了继续调查 组织相容性抗原在种族中独有的抗原 美国，重点是黑人和美洲原住民。 承包商将从多方妇女筛选出血清 识别和获取能够识别抗原的试剂 这些人群独有。 即使已经做了很多工作 在过去的六年中，在此领域完成了 合同，仍然有很多人的HLA打字是 不完整，在器官移植时将它们放在不利的位置 是必须的。 对MHC抗原的完全鉴定将 为这些人群提供更好的匹配，改善移植物 生存和降低医疗保健成本，其中大部分是 联邦补贴。