ANIMAL HOLDING FACILITY

动物饲养设施

• 批准号: 3606959
• 负责人: LEANNE DENENNO
• 金额: $ 4.2万
• 依托单位: BIOQUAL, INC.
• 依托单位国家: 美国
• 财政年份: 1987
• 资助国家: 美国
• 起止时间: 1987-11-01 至 1993-10-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3606959
• 关键词: animal breeding; animal care; animal colony

The objectives of this contract are to provide a small animal facility capable of (1) maintaining a colony of mice, rabbits, rats and hamsters to support ongoing research in the areas of transplantation, cancer biology and diagnosis, and immunology. The research includes the study of the role of H-2 and T cell receptor products in the immune response of well-defined mouse strains to tumors and transplantation antigens; (2) breeding special congenic strains of mice not available commercially; (3) providing a technical staff capable of performing bleedings and injections of mice and rabbits, skin grafting of mice, injections and harvesting of mouse ascites tumors, and palpation of mice for detection of tumors; (4) maintaining a freezer bank of serologic products to be used in conjunction with these animals; and (5) cryopreservation of fertilized embryos for future retrieval of individual strains of mice. All animals will be supplied by the Government.

该合同的目标是提供一个小型动物设施 能够（1）维持小鼠，兔子，大鼠和仓鼠的菌落 支持在移植，癌症生物学领域正在进行的研究 和诊断和免疫学。 研究包括对角色的研究 良好定义的免疫反应中的H-2和T细胞受体产物 小鼠菌株对肿瘤和移植抗原； （2）繁殖特别 小鼠的先天性菌株在商业上无法获得； （3）提供 能够进行出血和注射小鼠的技术人员和 兔子，小鼠的皮肤接枝，注射和收获小鼠腹水 肿瘤和小鼠触诊以检测肿瘤； （4）维护 冰柜库的血清学产品与这些产品结合使用 动物; （5）未来受精胚的冷冻保存 检索单个小鼠菌株。 所有动物将由 政府。