OPERATIONS OFFICE

运营办公室

• 批准号: 2295022
• 负责人: JAMES MCTIGUE
• 金额: $ 25.85万
• 依托单位: SOCIAL AND SCIENTIFIC SYSTEMS, INC.
• 依托单位国家: 美国
• 财政年份: 1991
• 资助国家: 美国
• 起止时间: 1991-03-01 至 1996-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2295022
• 关键词: OPERATIONS; OFFICE

The specific research goals of the DAIDS are: to decrease or prevent the spread of infection by HIV, to curb disease progression in people who are infected by the virus but do not have symptoms, and to limit disease progression and mortality in people with AIDS while preserving a high quality of life. DAIDS supports both preclinical and clinical research directly geared toward developing new treatment and potential vaccines for AIDS. These research activities also include the basic science foundation needed to advance drug and vaccine development, including studies in epidemiology, HIV pathogenesis and biostatistics research. The purpose of this contract is t support the DAIDS Treatment Research Program (TRP) which is built around a large network of sites (ACTUs) that conduct multi-center clinical trials for evaluating potential new AIDS therapies. The program requires scientific, technical and operational support to facilitate and significantly reduce the time required to develop, implement and successfully conclude clinical trial protocols. Contract support will be provided within a research environment and consortium of organizations that comprise the AIDS Clinical Trials Group (ACTG). The ACTG brings together ACTU clinical investigators and their institutions, the ACTG Statistical Data and Analysis Center, the Food and Drug Administration (FDA), the pharmaceutical industry, HIV infected patient and their advocates and Treatment Research Program scientists and administrative personnel to make key decisions about AIDS treatment research issues and to implement and conduct clinical trials.

daid的具体研究目标是：减少或防止 艾滋病毒感染传播，遏制疾病的进展 被病毒感染但没有症状，以限制疾病 艾滋病患者的进步和死亡率，同时保持高 生活质量。 daids支持临床前和临床研究 直接旨在开发新的治疗和潜在疫苗 艾滋病。 这些研究活动还包括基础科学基金会 需要推进药物和疫苗开发，包括研究 流行病学，HIV发病机理和生物统计学研究。 该合同的目的是支持daids治疗研究 程序（TRP）是围绕一个大型站点网络（ACTU）构建的 进行多中心临床试验，以评估潜在的新辅助工具 疗法。 该计划需要科学，技术和运营 支持以促进并显着减少所需的时间 制定，实施并成功地结论临床试验方案。 合同支持将在研究环境中提供 组成艾滋病临床试验小组的组织联盟 （ACTG）。 该ACTG汇集了Actu临床研究人员及其 机构，ACTG统计数据和分析中心，食物和 药物管理局（FDA），制药业，艾滋病毒感染 患者及其拥护者和治疗研究计划科学家以及 行政人员做出有关艾滋病治疗的关键决定 研究问题并实施和进行临床试验。