Building a Digital Respiratory Disease Framework for COPD management in Central Appalachia

为阿巴拉契亚中部的慢性阻塞性肺病管理建立数字呼吸系统疾病框架

基本信息

批准号：
10480681
负责人：
STARLA KISER
金额：
$ 25.95万
依托单位：
MEDENTUM INNOVATIONS INC.
依托单位国家：
美国
项目类别：
财政年份：
2022
资助国家：
美国
起止时间：
2022-09-26 至 2023-11-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10480681
关键词：
Address Adoption American Appalachian Region Artificial Intelligence Artificial Intelligence platform Behavioral Biometry Caring Cause of Death Chronic Disease Chronic Obstructive Pulmonary Disease Clinic Clinic Visits Clinical Communication Communities Companions Computer software Cost Savings Cost of Illness County Data Data Collection Data Set Devices Diagnosis Disease Disease Management Electronic Health Record Environmental Risk Factor Geography Goals Hand Health Health care facility Health system Home Hospitalization Incidence Insurance Knowledge Lead Measures Medical Medical History Mississippi Modeling Monitor Morbidity - disease rate Non-Malignant Outcome Oxygen Ozone Patient Triage Patients Phase Physicians Physiologic pulse Population Poverty Preventive Provider Pulse Oximetry Questionnaires Reading Records Respiration Respiratory Disease Respiratory Signs and Symptoms Risk Risk Factors Rural Rural Community Rural Population Secure Self Administration Self Management Small Business Innovation Research Grant Specialist Steroids Stethoscopes Surveys Symptoms Technology Telemedicine Telephone Temperature Testing Time Travel Treatment Cost Triage Uninsured Virginia Visit Weather adherence rate artificial intelligence algorithm base commercial application cost demographics design digital disorder control effective therapy evidence base handheld equipment health care quality health disparity improved innovation intelligent algorithm mortality remote monitoring respiratory respiratory health rural America rural Americans rural area rural dwellers satisfaction sensor smartphone Application social social culture social factors socioeconomics sound standard of care technological innovation telehealth treatment planning usability wearable device

项目摘要

PROJECT SUMMARY/ABSTRACT Compared to urban residents, rural communities have higher rates of chronic obstructive pulmonary disease (COPD) with worse disease control, resulting in higher rates of morbidity and mortality. In general, rural residents suffer from higher poverty and uninsured rates, further compounded by geographic isolation and limited access to quality healthcare. This and other social factors have resulted in higher incidence and worse outcomes of nearly every chronic disease. Telehealth holds promise to address these challenges and expand access to specialist care in these communities, but qualitative telehealth visits often lack necessary patient data for physicians to make informed management decisions. Telemedicine is also often hindered by limited broadband access in rural areas. Wearable technologies for remote monitoring suffer similar limitations, and, due to cost and burdensome daily engagement requirements, lead to poor adherence rates in an older, sicker population. To address these challenges, Medentum is developing an affordable and accessible, multi-functional, home-use device featuring a camera, low-cost sensors (temperature, pulse oximeter) and a digital stethoscope. A companion phone application allows the recording of demographics, sociocultural data, medical history, and symptoms, and guides the patient to collect their biometric readings with the handheld device. Without the necessity of broadband, the patient can transmit their information securely to a remote physician/chronic disease specialist who can make a diagnosis and treatment plan. For this SBIR, Medentum will adapt its device and software platform for respiratory disease, layering it with artificial intelligence (AI) algorithms, to create a digital respiratory disease framework (DRDF) that empowers self-management of COPD. The aims of this SBIR are to 1) study the usability and feasibility of this COPD respiratory framework in a rural Central Appalachian population of 75 patients in Southwest Virginia and 2) build preliminary AI algorithms that autonomously predict COPD exacerbation risk by analyzing low burden variables including risk factors (social, behavioral, environmental), symptoms, COPD Assessment tests, and device biometrics (temperature, pulse, oxygen saturation, respiration rate and breath sounds). In Phase II, the platform will incorporate smart triggers that will alert patients if certain environmental risk factors are met, prompting them to engage with the platform. The smart algorithms will then automatically predict their COPD exacerbation risk, ultimately triaging them to appropriate treatment. Predicting and pre-empting disease exacerbation by facilitating early connections to medical providers for prompt and effective treatment will have an enormous impact on health outcomes and treatment costs for rural COPD patients. Ultimately, this platform will augment COPD self-management, promote preventive respiratory care, and disseminate evidence-based COPD treatments, all designed to reduce the significant health disparities in a remote, underserved Central Appalachian population with worse respiratory outcomes.

项目概要/摘要与城市居民相比，农村社区慢性阻塞性肺病患病率更高（慢性阻塞性肺病）疾病控制较差，导致发病率和死亡率较高。一般来说，农村居民贫困率和无保险率较高，地理隔离和准入限制进一步加剧了这种情况优质的医疗保健。这一社会因素和其他社会因素导致了该病的发病率更高，结果更差。几乎所有慢性疾病。远程医疗有望解决这些挑战并扩大获得服务的机会这些社区的专家护理，但定性远程医疗就诊往往缺乏必要的患者数据医生做出明智的管理决策。远程医疗也经常受到宽带有限的阻碍农村地区的访问。用于远程监控的可穿戴技术也受到类似的限制，并且由于成本繁重的日常参与要求导致老年人、病情较重的人群的依从率很低。为了应对这些挑战，Medentum 正在开发一种价格实惠、易于使用、多功能、家用的产品该设备配有摄像头、低成本传感器（温度、脉搏血氧计）和数字听诊器。一个配套的手机应用程序可以记录人口统计数据、社会文化数据、病史和症状，并指导患者使用手持设备收集生物识别读数。如果没有宽带的必要性，患者可以将其信息安全地传输给远程医生/慢性病可以制定诊断和治疗计划的专家。对于此 SBIR，Medentum 将调整其设备并针对呼吸系统疾病的软件平台，将其与人工智能 (AI) 算法分层，创建数字化呼吸系统疾病框架（DRDF），增强慢性阻塞性肺病的自我管理能力。该 SBIR 的目标是 1) 研究该 COPD 呼吸框架在阿巴拉契亚中部农村人口中的可用性和可行性弗吉尼亚州西南部的 75 名患者和 2) 构建了初步的人工智能算法来自主预测慢性阻塞性肺病通过分析包括风险因素（社会、行为、环境）在内的低负担变量来确定恶化风险，症状、COPD 评估测试和设备生物识别（温度、脉搏、血氧饱和度、呼吸率和呼吸音）。在第二阶段，该平台将纳入智能触发器，如果某些情况会向患者发出警报环境风险因素得到满足，促使他们参与该平台。然后智能算法将自动预测他们的慢性阻塞性肺病恶化风险，最终对他们进行适当的治疗。预测并通过促进与医疗提供者的早期联系以迅速和有效地预防疾病恶化有效的治疗将对农村慢性阻塞性肺病的健康结果和治疗费用产生巨大影响患者。最终，该平台将增强慢性阻塞性肺病的自我管理，促进预防性呼吸护理，并传播基于证据的慢性阻塞性肺病治疗方法，所有这些都是为了减少各地区显着的健康差距偏远、服务水平低下的阿巴拉契亚中部人口，其呼吸系统状况较差。