ACADEMIC AWARD IN VASCULAR DISEASE

血管疾病学术奖

• 批准号: 2210630
• 负责人: WILLIAM Read HIATT
• 金额: $ 18.58万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 1993
• 资助国家: 美国
• 起止时间: 1993-07-23 至 1998-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2210630
• 关键词: blood vessel disorder; comprehensive care; curriculum; early diagnosis; echocardiography; exercise; gene expression; health care service evaluation; health science research; human subject; human therapy evaluation; ischemia; magnetic resonance imaging; medical education; muscle metabolism; oxygen therapy; patient care management; pulmonary circulation obstruction; pulmonary hypertension; training

The Academic Award in Vascular Disease will be used to develop a comprehensive clinical, training, and research program in systemiC and pulmonary vascular diseases at the Center for Vascular Diseases, University of Colorado Health Sciences Center. The mission of the Center will be to provide comprehensive evaluation, and medical and surgical treatment, of patients with peripheral arterial disease, severe pulmonary hypertension, thrombophlebitis, hypercoagulable states, chronic venous disease, cerebrovascular disease and vasospastic diseases. Laboratory support will include sophisticated clinical vascular laboratories, heart catheter laboratories, MRI imaging to assess the systemic and pulmonary circulations, and a coagulation laboratory. An extensive patient registry has been established to monitor the clinical characteristics and status of all patients with vascular diseases in the University system. The Center will provide specialized training for medical students, surgical and medical house staff, graduate students, and Pulmonary and Cardiology fellows. The Center will support two dedicated vascular fellows each year for specialized clinical and research training. Clinical research will focus on the development of exercise rehabilitation and new drug therapies for claudication. Basic vascular biology research will address the role of disordered cell proliferation in the pathogenesis of severe pulmonary hypertension, as well as the mechanisms of the regulation of pulmonary vascular tone. The effects of ischemia on skeletal muscle metabolism and mitochondrial gene expression will also be evaluated. These clinical, training and research programs will be highly integrated, with weekly clinical specialty conferences to coordinate patient care, and a monthly vascular grand rounds as a focus for the training and research activities. Thus, this Center for Vascular Disease will provide a unique mechanism for the integration of clinical care in vascular diseases, the education of clinician/scientists in systemic and pulmonary vascular diseases, and for clinical and basic vascular biology research.

血管疾病的学术奖将用于开发 全身和全面的临床，培训和研究计划 血管疾病中心的肺血管疾病， 科罗拉多大学健康科学中心。任务 中心将提供全面的评估，医疗和 外周动脉疾病患者的手术治疗 严重的肺动脉高压，血栓性静脉炎，可高凝 州，慢性静脉疾病，脑血管疾病和血管疾病 疾病。 实验室支持将包括复杂的临床 血管实验室，心脏导管实验室，MRI成像 评估系统和肺循环，以及凝结 实验室。已经建立了广泛的患者注册表 监视所有患者的临床特征和状态 大学系统中的血管疾病。中心将提供 医学生，外科和医疗机构的专业培训 员工，研究生以及肺和心脏病研究员。这 中心每年将支持两个专用的血管研究员 专门的临床和研究培训。临床研究将 专注于运动康复和新药的发展 通风疗法。基本的血管生物学研究将 解决无序细胞增殖在发病机理中的作用 严重的肺高血压以及 调节肺血管张力。缺血对 骨骼肌代谢和线粒体基因表达也将 进行评估。这些临床，培训和研究计划将是 高度整合，每周一次的临床专业会议 协调患者护理和每月的血管大弹作为重点 用于培训和研究活动。因此，这个中心 血管疾病将为整合提供独特的机制 血管疾病的临床护理，教育 系统性和肺血管疾病的临床医生/科学家，以及 用于临床和基本血管生物学研究。