OPIOID INVOLVEMENT IN NEUROIMMUNE STRESS RESPONSE

阿片类药物参与神经免疫应激反应

• 批准号: 5209720
• 负责人: GEORGE B STEFANO
• 金额: --
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/5209720
• 关键词: Bivalvia; cellular immunity; cilium /flagellum motility; dopamine; drug abuse; electrostimulus; granulocyte; immune adherence reaction; immunocytochemistry; ligands; lymphocyte; monocyte; naloxone; neural information processing; neurobiology; neuropeptides; neurotransmitter metabolism; neurotransmitter receptor; neurotransmitters; stereochemistry; stress

The proposed Old Westbury Neuroscience Research Institute will increase the research potential of the SUNY/College at Old Westbury, the faculty and our minority undergraduate students. The goal for the immediate future will be to provide research support for the faculty so that they may obtain R01-type grants, create an environment for the further development of research at the College and increase minority student representation in graduate programs. Over the longer term, the goal will be to increase the numbers of minority students in careers in mental health and drug abuse treatment and prevention. The College is ideally suited to carry out this mission because it has a high percentage of minority students who choose science as a major and a faculty experienced in research and the training of students in neuroscience research with special interests in molecular and cellular approaches. The proposed MIRDP student curriculum is built on a core mental health-neuroscience concentration that already exists. The MIRDP faculty and students will be involved with modern neurobiological-immune techniques (receptor binding, neuroendocrine/behavior, neurotransmitter/ modulator identification, image analysis), and will work as well on many levels (molecular, cellular and organismic) concerned with the elucidating neuropeptide mechanisms. The program will provide seminars/lectures and workshops related to ADAMHA areas. The students will have an opportunity to earn entrance into the existing ADAMHA-MARC Program as well as our Society for Neuroscience Chapter. Our program stresses meritorious mental health-drug abuse research as an immediate goal or measure of our activity. The career choices of the students will be broadened, and their expertise and awareness of mental health and related areas will increase. This program offers a strong "wet-lab" foundation to foster mental health and drug abuse interests and build on these areas as career options as well as develop both faculty research and institutional advancement in this area.

拟议的旧韦斯特伯里神经科学研究所将增加 旧韦斯特伯里的纽约州/学院的研究潜力，教职员工和我们 少数族裔本科生。近期未来的目标将是 为教师提供研究支持，以便他们获得 R01型赠款，为进一步发展创造一个环境 在学院进行研究，增加少数学生的代表性 研究生课程。从长远来看，目标是增加 从事心理健康和药物滥用职业的少数族裔学生人数 治疗和预防。该学院非常适合执行此操作 任务是因为它有很高的选择 科学是研究和培训方面的主要和教师 具有分子特殊兴趣的神经科学研究的学生 和细胞方法。拟议的MIRDP学生课程建立在 已经存在的核心心理健康 - 神经科学浓度。这 MIRDP教师和学生将参与现代 神经生物学免疫技术（受体结合， 神经内分泌/行为，神经递质/调节剂识别，图像 分析），并且在许多级别（分子，细胞和 有机体）与阐明神经肽机制有关。这 计划将提供与Adamha有关的研讨会/讲座和讲习班 区域。学生将有机会赢得进入 现有的Adamha-Marc计划以及我们的神经科学协会 章。我们的计划强调了功绩性的心理健康滥用研究 作为我们活动的直接目标或衡量标准。职业选择 学生将被扩大，他们的专业知识和对心理的认识 健康及相关领域将增加。该程序提供了强大的 “湿lab”基金会，以促进心理健康和药物滥用兴趣以及 以这些领域作为职业选择以及发展两种教师 该领域的研究和机构进步。