ELECTRONIC OPTICAL BENCH

电子光学平台

• 批准号: 2163995
• 负责人: LEO J MAGUIRE
• 金额: $ 13.27万
• 依托单位: MAYO CLINIC ROCHESTER
• 依托单位国家: 美国
• 财政年份: 1993
• 资助国家: 美国
• 起止时间: 1993-08-01 至 1996-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2163995
• 关键词: computer program /software; cornea; eye laser surgery; eye refraction disorder; eye refractometry; human subject; human therapy evaluation; keratoconus; mathematical model; model design /development; optics; postoperative state; preoperative state; refractive keratoplasty; statistics /biometry

DESCRIPTION: (Investigator's Abstract). Keratorefractive surgery changes refractive error by permanently altering the optical performance of the cornea. These new surfaces differ optically from their preoperative counterparts. Topography and psychophysical studies show clinically significant differences in structural stability, quality of resolution (central and peripheral vision), depth of field, reproducibility of clinical refraction, pupil effects on refractive error, and pupil effects on glare and blur in both the central and peripheral visual field. The severity of optical aberration will be exacerbated by inadequate preoperative screening for corneal disease. Any surgeon or design error will exacerbate the problem. Hundreds of thousands of Americans have had keratorefractive surgery. It seems logical to develop methods that measure the optical performance of the keratorefractive surface in as direct and accurate way as possible; and to try to correlate topography and psychophysical measurements with measurements of the optical performance of the cornea. Without this knowledge, it is impossible to assess whether iatrogenically induced corneal aberration from keratorefractive surgery will accelerate the onset of visual dysfunction from the two most common causes of visual loss in the aging population-cataract and age-related macular degeneration. To that end, we are developing a ray tracing system to model the optical performance of the cornea. This grant seeks to refine our model into a system that accurately assesses the optical performance of optically aberrated corneas. It will evaluate the precision of topography system the electronic optical bench uses to describe the lends characteristics of the cornea; improve and validate the ray tracing algorithms the model uses to generate lens throughput from the corneal topography data; develop autofocus programs that identify along the optical axis the best resolved image generated by the ray tracing system; and apply the optical bench method to studies of keratorefractive surgery.

描述：（研究者的摘要）。 角疗法手术 通过永久更改光学性能来更改折射率 角膜。 这些新表面与它们的光学不同 术前对应物。 地形和心理学研究表明 结构稳定性的临床显着差异，质量 分辨率（中央视觉和外围视觉），景深， 临床折射的可重复性，学生对折射的影响 错误，以及对中央和中央的眩光和模糊的瞳孔影响 外围视野。 光畸变的严重程度将是 因术前筛查的角膜疾病而加剧。 任何外科医生或设计错误都会加剧问题。 数百个 成千上万的美国人接受了肾上腺菌方手术。 它似乎 逻辑来开发测量的方法 尽可能直接，准确的方式；和 试图将地形和心理物理测量与 角膜光学性能的测量。 没有这个 知识，无法评估医源性是否诱导 角膜折射手术的角膜像差将加速 视觉功能的视觉功能障碍的发作来自两个最常见的视觉原因 衰老的种群 - 帕拉克和与年龄有关的黄斑的损失 退化。 为此，我们正在开发一个射线追踪系统 建模角膜的光学性能。 这项赠款试图完善 我们进入准确评估光学性能的系统 光学差的角膜。 它将评估 地形系统电子光学台用来描述借贷 角膜的特征；改进和验证射线跟踪 该模型用于从角膜生成镜头吞吐量的算法 地形数据； 开发自动对焦程序，以识别 光轴是由射线示踪产生的最佳解决图像 系统;并将光学基准方法应用于研究 角疗法手术。