EXERCISE TRAINING IN FUNCTIONALLY IMPAIRED OLDER WOMEN

功能障碍老年女性的运动训练

• 批准号: 2053013
• 负责人: MARIA A FIATARONE
• 金额: $ 36.5万
• 依托单位: TUFTS UNIVERSITY BOSTON
• 依托单位国家: 美国
• 财政年份: 1993
• 资助国家: 美国
• 起止时间: 1993-05-10 至 1998-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2053013
• 关键词: balance; bioenergetics; body composition; clinical trials; exercise; female; functional ability; gait; human old age (65+); human subject; immunity; longitudinal human study; muscle strength; nutrient intake activity; nutrition of aging; nutrition related tag; physical fitness; therapy compliance; training

Functional impairment becomes increasingly prevalent with age. Declines in performance of the cardiovascular and musculoskeletal systems, whether from specific diseases, undernutrition, or aging itself, may be associated with impaired functional abilities. However, it is not known if improvements in muscle function and endurance capacity achieved in such a population would result in improved functional independence as well. The proposed investigation would test the hypothesis that a year- long exercise intervention in elderly women would result in clinically important health benefits as defined by measures of functional status and ambulatory abilities. In addition, the critical relationships between nutritional status, energy expenditure, body composition, physical functioning, and response to training in elderly women will be explored. One hundred community-dwelling women over the age of 70 with mild to moderate functional impairment will be enrolled in a one year controlled clinical trial. Subjects will be randomized to an experimental group which will participate in three days per week of endurance and strength training or a control group which will receive weekly mild stretching exercises only. High intensity resistance training of the upper and lower extremities will be achieved using dynamic weight machines and static forearm exercise. Walking and stair climbing at moderate intensity will comprise the endurance training intervention. At baseline, 6 months, and post-training, subjects will be characterized with respect to their body composition, nutritional status, endurance capacity, muscle strength, gait and balance, functional status, and physical and psychological health.

功能障碍随着年龄的增长而变得越来越普遍。 下降 在心血管和肌肉骨骼系统的性能中 从特定疾病，营养不良或衰老本身中可能是 与功能能力受损相关。 但是，这是不知道的 如果肌肉功能和耐力能力的提高 这样的人口将改善功能独立性 出色地。 拟议的调查将检验以下假设：一年 长期对老年妇女进行长期运动干预将导致临床 功能状况衡量和 卧床能力。 此外，批判关系 在营养状况，能量消耗，身体之间 组成，身体功能和对老年人培训的反应 妇女将被探索。 70岁以上的一百个社区妇女温和到 中等功能障碍将在一年的控制中注册 临床试验。 受试者将被随机分为实验组 这将参加每周三天的耐力和力量 培训或对照组，将每周接收轻度拉伸 仅练习。 上部和 下肢将使用动态的重量机和 静态前臂运动。 步行和楼梯攀登 强度将包括耐力训练干预措施。 在 基线，6个月和训练后，受试者将被表征 关于其身体成分，营养状况，耐力 能力，肌肉力量，步态和平衡，功能状态和 身体和心理健康。