Molecular Biology Across Scales Training Program

跨尺度分子生物学培训计划

• 批准号: 10555915
• 负责人: David Bilder
• 金额: $ 180.56万
• 依托单位: UNIVERSITY OF CALIFORNIA BERKELEY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-07-01 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10555915
• 关键词: Molecular Biology; Training Programs

Project Summary / Abstract Molecular Biology Across Scales (MBAS) is a new multidisciplinary predoctoral training program that will develop the next generation of researchers discovering how molecules, cells, and tissues interact to create life and how this information can advance human health. MBAS will be the only graduate program at the University of California, Berkeley that supports broad-based training in multiple disciplines of molecular biology, rather than specialization within a particular discipline. This perspective has driven many of the transformative biological discoveries of recent years, including several made by MBAS faculty. MBAS will draw its students and faculty from the Department of Molecular & Cell Biology (MCB) Graduate Program, uniting those who tackle fundamental research problems at length scales ranging from individual molecules to complex biochemical systems to whole organisms. It will appoint 40 students (20 first-year trainees annually for a two-year term) with a target of 30% from historically excluded groups in the biological sciences. MBAS will provide diverse training opportunities for its diverse student body, encouraging each trainee to explore a wide range of research fields in their early years and identify those that most fully engage their individual passion. MBAS students will be required to publish a first-author paper and graduate with a mean time to degree of 5.5 years. The curriculum will impart broad conceptual knowledge, creative and critical thinking, mastery of experimental logic and methods, application of computational and quantitative approaches, rigorous analysis and interpretation of results, clear and fluent communication of findings, and incorporation of responsible, safe, and ethical practices. Students will choose formally-trained mentors from a faculty of 75 nationally recognized leaders who represent a wide choice of research areas and technical approaches, use state-of-the-art facilities, and work in an interactive, diverse and collaborative environment. MBAS will provide training, oversight, and support for its participating faculty, and will carefully monitor the progress of its trainees. Students will be well-supported with inclusive learning communities, rigorous and clear expectations, expert advising, and a program design that accounts for differences in preparation. Innovative training elements include new courses and enhanced content in responsible conduct of research and reproducibility, quantitative biology and data science, lab safety, and scientific writing. To further strengthen recruitment and retention, MBAS will mount initiatives to bolster diversity, equity, inclusion, and belonging. New programs will be piloted and evaluated with the goal of scaling the most successful of them to benefit all trainees within MCB. Professional skills development, experiential learning opportunities, and career counseling will prepare trainees for research-related careers of their choosing in academia, industry, government, non-governmental organizations, and beyond. In sum, MBAS will provide an early and persistent emphasis on multidisciplinary training, centered around the student experience, for a flexible and individually directed path to a successful career in the biomedical workforce.

项目摘要 /摘要 跨量表（MBA）的分子生物学是一个新的多学科训练计划，将 发展下一代研究人员，发现分子，细胞和组织如何相互作用以创造生命 以及这些信息如何改善人类健康。 MBA将是大学唯一的研究生课程 加利福尼亚州的伯克利，支持分子生物学多个学科的广泛培训，而不是 在特定学科中的专业化。这种观点驱动了许多变革性生物学 近年来发现的发现，包括MBAS教师制造的一些。 MBA将吸引其学生和教师 来自分子与细胞生物学系（MCB）研究生课程，将解决方案团结起来 从单个分子到复杂的生化的基本研究问题的长度尺度不等 整个生物的系统。它将任命40名学生（每年有20名一年级学员，任期两年） 生物科学中历史上排除的群体的目标为30％。 MBA将提供多种培训 各种各样的学生团体的机会，鼓励每个学员探索广泛的研究领域 他们的早年，确定那些最充分吸引个人激情的人。将需要MBA学生 出版第一任撰文书和毕业生，平均时间达到5。5年。课程将提供 广泛的概念知识，创造性和批判性思维，掌握实验逻辑和方法， 计算和定量方法的应用，严格的分析和结果的解释，清晰 以及调查结果的流利沟通，以及负责，安全和道德实践的结合。学生会 从75位全国认可的领导人的教职员工中选择正式训练的导师，他们代表了广泛的选择 研究领域和技术方法，使用最先进的设施，并在互动，多样化 和协作环境。 MBA将为其参与教师提供培训，监督和支持，以及 将仔细监视其受训者的进度。学生将得到充分支持的包容性学习 社区，严格而清晰的期望，专家咨询和计划设计 准备差异。创新的培训元素包括新课程和增强内容 负责研究和可重复性，定量生物学和数据科学，实验室安全以及 科学写作。为了进一步加强招聘和保留，MBA将采取行动以加强多样性， 公平，包容和归属。新程序将进行试验和评估，以最大程度地扩展 他们成功地使MCB中的所有学员受益。专业技能发展，体验学习 机会和职业咨询将为受训者提供与研究相关的职业的准备 学术，工业，政府，非政府组织以及其他地区。总而言之，MBA将提供 围绕学生体验的早期和持续强调多学科培训，以灵活 并在生物医学劳动力中单独指导了成功职业生涯的道路。