The Don S. Fredrickson Lipid Research Conference

唐·弗雷德里克森脂质研究会议

基本信息

批准号：
10539150
负责人：
Gregory A Graf
金额：
$ 1.7万
依托单位：
UNIVERSITY OF KENTUCKY
依托单位国家：
美国
项目类别：
财政年份：
2022
资助国家：
美国
起止时间：
2022-08-01 至 2023-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10539150
关键词：
Address Adipose tissue Apolipoproteins Basic Science Biological Models Body Composition Cardiometabolic Disease Cardiovascular Diseases Cardiovascular system Ceramides Classification Clinical Clinical Investigator Collaborations Development Diabetes Mellitus Disease Progression Dyslipidemias Ensure Faculty Fostering Goals Heart Hypertension Hypertriglyceridemia Institutes Institution Insulin Resistance Kentucky Lipids Lipoproteins Metabolic Diseases Metabolic syndrome Metabolism Midwestern United States Mitochondria Modeling Molecular Genetics Names National Heart, Lung, and Blood Institute North Carolina Obesity Oral Participant Research Research Activity Research Personnel Research Project Grants Role Science Scientist Seminal Senior Scientist Students Talents Tangier Disease Technology Thinking Training Underrepresented Populations United States National Institutes of Health Universities Wisconsin cardiovascular risk factor career career development clinically significant early-career faculty experience innovation insight lectures lipid metabolism medical schools meetings new technology novel posters programs relative cost social social engagement symposium translational scientist

项目摘要

ABSTRACT The Don S. Fredrickson Lipid Research Conference (FLRC) brings together scientists and trainees investigating the impact of lipid and lipoprotein metabolism on the development and treatment of Cardiometabolic Disease. The FLRC is named after the late Don S. Fredricks who as the director of the National Heart Institute (now the NHLBI) from 1966 – 1974 and later the NIH, developed the clinical classification for dyslipidemias (Type I-V), described Tangier’s Disease, and made seminal discoveries in lipoprotein metabolism. Most importantly, he trained both basic and clinical scientists and practitioners who have had a tremendous impact on the field of lipoprotein metabolism. Since 2016 the FLRC has employed a rotating institutional host model, the first of which was held at the University of Kentucky in conjunction with the Saha Cardiovascular Research Center Research Day. The FLRC has since been hosted by Vanderbilt University, the University of Cincinnati. The 2022 conference will be hosted by Duke University and the University of North Carolina in conjunction with the North Carolina Diabetes Research Day. The FLRC will be hosted by Vanderbilt University in 2023 and the Medical College of Wisconsin in 2024. Keynote Lectures at the 2022 Fredrickson conference include Karen Mohlke, University of North Carolina and Deborah Muoio, Duke University on Days 1 and 3 of the conference. The scientific sessions include Novel Models in Lipid Metabolism, Adipose Tissue, Lipoprotein Metabolism, and Lipids and Body Composition. Day 2 of the conference will be sponsored by the North Carolina Diabetes Research Center. The agenda includes additional scientific sessions; multiple “Poster Pitch” sessions (5-7, 90-second presentations by trainees) and two judged poster sessions. The FLRC places a strong emphasis students and fellows, early career faculty, and underrepresented groups. The combined agenda affords every trainee in attendance the opportunity to present their research on stage, network with leaders in the field, and broaden their scope and understanding of research in lipid metabolism and Cardiometabolic Diseases. Our format encourages informal interactions between scientists at all levels, providing an innovative approach to the exchange of ideas and synthesis that will move the field of lipid research forward. The conference will have high impact as the program spans basic science discovery to clinical significance. It is therefore expected that the meeting will provide new insights not only into basic aspects of lipid metabolism, but also how to treat, and ultimately cure, a wide variety of Cardiometabolic Disease states.

抽象的 Don S. Fredrickson 脂质研究会议 (FLRC) 汇集了科学家和学员研究脂质和脂蛋白代谢对发育和发育的影响 FLRC 是以已故的 Don S. Fredricks 的名字命名的。 1966 年至 1974 年担任国家心脏研究所（现 NHLBI）所长，随后又担任 NIH 制定了血脂异常的临床分类（I-V 型），描述了丹吉尔的疾病，并在脂蛋白代谢方面取得了开创性的发现，最重要的是，他进行了训练。对医学产生巨大影响的基础和临床科学家和实践者脂蛋白代谢领域。自 2016 年以来，FLRC 采用了轮换机构主办模式，其中第一个是与萨哈心血管研究中心联合在肯塔基大学举行研究日由范德比尔特大学主办。 2022 年会议将由杜克大学和北方大学主办。卡罗莱纳州将与北卡罗来纳州糖尿病研究日同时举行。 2023 年由范德比尔特大学主办，2024 年由威斯康星医学院主办。 2022 年 Fredrickson 会议的主题演讲包括北方大学的 Karen Mohlke 杜克大学的 Carolina 和 Deborah Muoio 在科学会议的第一天和第三天。会议包括脂质代谢、脂肪组织、脂蛋白代谢的新模型，会议第二天将由北方主办。卡罗莱纳州糖尿病研究中心的议程包括多个科学会议； “海报推介”会议（学员进行 5 至 7 次、90 秒的演示）和两张经过评审的海报 FLRC 非常重视学生和研究员、早期职业教师和合并议程为每位参加的学员提供了代表性不足的群体。有机会在舞台上展示他们的研究成果，与该领域的领导者建立联系，并拓宽视野他们对脂质代谢和心脏代谢疾病研究的范围和理解。我们的形式鼓励各级科学家之间的非正式互动，提供思想交流和合成的创新方法将推动脂质领域的发展由于该计划涵盖基础科学，因此会议将产生巨大影响。因此，预计这次会议将提供新的发现和临床意义。不仅深入了解脂质代谢的基本方面，还了解如何治疗，并最终治愈多种心脏代谢疾病状态。