UAB Cardiovascular Disease Predoctoral Training Program in Biostatistics and Epidemiology

UAB心血管疾病生物统计学和流行病学博士前培训项目

• 批准号: 10531226
• 负责人: Marguerite R Irvin
• 金额: $ 18.9万
• 依托单位: UNIVERSITY OF ALABAMA AT BIRMINGHAM
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-12-01 至 2025-11-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10531226
• 关键词: Biometry; Cardiovascular Diseases; Epidemiology; Training Programs; pre-doctoral; Biometry; Cardiovascular Diseases; Epidemiology; Training Programs; pre-doctoral

The increasing availability of “big data” has transformed the training required to advance our understanding of the pathophysiology of cardiovascular disease (CVD), the identification of patient-level and public health approaches to prevent its occurrence and aspects of quality of care for patients with CVD and its risk factors. The goal of the proposed pre-doctoral National Heart, Lung, and Blood Institute T32 CVD training grant is to engage and empower biostatistics and epidemiology students with a strong foundation in both disciplines so they will be positioned to lead the design, conduct and analysis of the big data that are being collected in the 21st century. Located in the Southeastern US, an area with the highest heart disease death rates, the University of Alabama at Birmingham (UAB) has been at the forefront of CVD biostatistics and epidemiology research for over 25 years. The Departments of Biostatistics and Epidemiology are internationally recognized for leading randomized trial coordinating centers, serving as the coordinating center and field sites for epidemiology studies, conducting analyses of health insurance claims and electronic medical record data, and developing new methods for statistical genetics/genomics. For this T32 program, we are requesting funding for a total of 12 pre-doctoral trainees over the course of 5 years including 2 new trainees in each of years 1 through 3 and 3 new trainees in each of years 4 and 5. Trainees enrolled in the T32 program will receive a strong foundation in the pathophysiology and epidemiology of CVD, skills to design and conduct observational research, training on rigor and reproducibility in CVD research, familiarity with how real-world data are collected and analyzed, experience conducting big data analytics including omics data, grant writing experience, and networking opportunities within UAB and the larger scientific community of CVD researchers. Pre-doctoral trainees will complete activities that provide added value to their doctoral programs in biostatistics and epidemiology including didactic cross-training courses, a grant writing class and workshop, research immersions in three areas of big data, professional development workshops, and CVD seminars and a journal club. We have designed three workshops for this T32 grant including an 8-week summer training program on CVD, a high performance computing boot camp and a workshop on team science and communication. The training program’s capstone experience is a mentored research project resulting in a peer-reviewed manuscript. The program will be led by Drs. Hemant Tiwari and Paul Muntner, full professors in Biostatistics and Epidemiology, respectively, with strong mentoring records and program development experience. We have received the commitment from 14 primary mentors and 11 secondary mentors from the Departments of Biostatistics and Epidemiology. An additional 21 faculty members from across UAB have committed to serve as content mentors. The proposed pre-doctoral T32 Training Program will produce a cadre of biostatisticians and epidemiologists prepared to lead CVD research studies that address the priorities of NHLBI.

“大数据”的可用性越来越多，改变了我们对我们对的理解所需的培训 心血管疾病（CVD）的病理生理学，患者级别和公共卫生的鉴定 防止CVD患者及其危险因素的护理质量的发生和方面的方法。 拟议的博士前国家心脏，肺部和血液研究所T32 CVD培训补助金的目标是 在这两个学科中都具有良好基础的生物统计学和流行病学专业的学生能力 他们将被定位，以领导正在收集的大数据的设计，进行和分析 21世纪。位于美国东南部，是心脏病死亡率最高的地区 阿拉巴马大学伯明翰（UAB）一直处于CVD生物统计学和流行病学的最前沿 研究超过25年。生物统计学和流行病学部门是国际公认的 用于领先的随机试验协调中心，充当协调中心和现场地点 流行病学研究，对健康保险索赔和电子病历数据进行分析，以及 开发用于统计遗传学/基因组学的新方法。对于此T32计划，我们要求为 在5年的过程中，共有12名博士前学员，其中包括2名新学员1 在4年和5年内，通过3和3名新学员。参加T32计划的学员将获得 CVD的病理生理学和流行病学，设计和进行观察性的技能 CVD研究中严格和可重复性的研究，对现实数据的熟悉程度的培训 收集和分析，进行大数据分析的经验，包括OMICS数据，赠款写作 UAB和更大的CVD研究人员科学界的经验和网络机会。 博士前学员将完成为生物统计学博士课程提供附加价值的活动 和流行病学，包括教学交叉训练课程，赠款写作课和讲习班，研究 浸入大数据的三个领域，专业发展研讨会和CVD SEMIAR和杂志 俱乐部。我们为这项T32赠款设计了三个研讨会，包括一项为期8周的夏季培训计划 CVD，高性能计算训练营和团队科学与沟通的研讨会。这 培训计划的顶峰经验是一个受过指导的研究项目，由同行评审 手稿。该程序将由Drs领导。 Hemant Tiwari和Paul Muntner，生物统计学的全部教授 和流行病学分别具有强大的心理记录和计划发展经验。我们 已经收到了14位主要导师和11位二级导师的承诺 生物统计学和流行病学。来自UAB的另外21名教职员工已承诺为服务服务 作为内容导师。拟议的博士前T32培训计划将产生一群生物统计学家 流行病学家准备领导CVD研究，以解决NHLBI的优先事项。