The Administrative Core of Prefrontal Cortex, Cognition, and Speech Symptoms in Parkinson’s disease (PRECIS-PD)

帕金森病的前额皮质、认知和言语症状的管理核心 (PRECIS-PD)

• 批准号: 10490435
• 负责人: Nandakumar Narayanan
• 金额: $ 9.31万
• 依托单位: UNIVERSITY OF IOWA
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-17 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10490435
• 关键词: Address; Administrator; Archives; Benchmarking; Biometry; Budgets; Clinical; Clinical Sciences; Code; Cognition; Cognitive; Communication; Communication Research; Communities; Data; Data Analyses; Data Set; Ensure; Environment; Feedback; Fostering; Functional disorder; Funding; Future; General Population; Goals; Grant; Institutes; Iowa; Leadership; Link; National Institute of Neurological Disorders and Stroke; Neurology; Neurosciences; Parkinson Disease; Patients; Persons; Prefrontal Cortex; Preparation; Principal Investigator; Publications; Randomized; Reproducibility; Research; Research Design; Research Personnel; Research Project Grants; Speech; Symptoms; Translational Research; Universities; Vision; data analysis pipeline; data sharing; epidemiology study; experience; improved; innovation; meetings; member; neuroinformatics; neurophysiology; programs; relating to nervous system; synergism

Abstract The Administrative Core of Prefrontal Cortex, Cognition, and Speech Symptoms in Parkinson’s disease (PRECIS-PD) will facilitate new collaborative projects that will advance our understanding of the prefrontal cortex (PFC) in cognitive and speech dysfunction in Parkinson’s disease (PD). Led by Dr. Nandakumar Narayanan (Program Director/Principal Investigator), this core will provide the leadership, oversight, and project management that will form the organizational basis for the proposed Exploratory Grant, as well as for a future NINDS Udall Center P50 application. The Administrative Core will promote research integration and synergies across projects and cultivate communication among our researchers and our internal and external committees. The University of Iowa will provide funding for a dedicated and experienced Research Administrator to manage the proposed Exploratory Grant. These efforts will be heavily buttressed by the outstanding research organizations at UI, including the Department of Neurology, the Iowa Neuroscience Institute (INI), and the Institute for Clinical and Translational Sciences (ICTS). The Administrative Core will provide focus, leadership, and vision for PRECIS-PD, foster open and effective research communication, develop pipelines for data analysis and data sharing, and ensure our research is robust, rigorous, and reproducible. This Administrative Core will manage all P20 projects to collect innovative preliminary data towards supporting a future P50 application. Our focus will be on communication and organization around high-quality neurophysiological data, and on cultivating an environment of transformational discovery that will inspire meaningful impact in the lives of PD patients.

抽象的 帕金森病的前额皮质、认知和言语症状的管理核心 (PRECIS-PD) 将促进新的合作项目，从而加深我们对 前额皮质 (PFC) 在帕金森病 (PD) 认知和言语功能障碍中的作用 Nandakumar Narayanan（项目总监/首席研究员），该核心将提供领导力， 监督和项目管理将构成拟议探索性项目的组织基础 Grant 以及未来的 NINDS Udall 中心 P50 应用程序将由行政核心进行推广。 跨项目的研究整合和协同作用，并培养研究人员之间的沟通 以及我们的内部和外部委员会将为专门的和外部的委员会提供资金。 经验丰富的研究管理员将负责管理拟议的探索性资助。 得到了伊利诺伊大学杰出研究机构的大力支持，其中包括 神经病学、爱荷华州神经科学研究所 (INI) 以及临床和转化科学研究所 （信息通信技术）。 行政核心将为 PRECIS-PD 提供重点、领导力和愿景，促进开放和 有效的研究交流，开发数据分析和数据共享的渠道，并确保我们 该管理核心将管理所有 P20 项目，以实现稳健、严谨和可重复的研究。 收集创新的初步数据以支持未来的 P50 应用。 围绕高质量的神经生理学数据进行沟通和组织，并培养 变革性发现的环境将对帕金森病患者的生活产生有意义的影响。