Novel Wiring Catheter for Crossing Complex Chronic Total Occlusions

用于穿越复杂慢性完全闭塞的新型导丝导管

• 批准号: 10483058
• 负责人: Nick Rydberg
• 金额: $ 30万
• 依托单位: MINNESOTA HEALTHSOLUTIONS CORPORATION
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-04-01 至 2025-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10483058
• 关键词: Affect; Algorithms; Amputation; Angioplasty; Arrhythmia; Arteries; Atherosclerosis; Blood Vessels; Cadaver; Calcium; Cardiac; Cardiovascular system; Catheters; Cause of Death; Cauterize; Cessation of life; Cholesterol; Chronic; Collaborations; Complex; Computer software; Consumption; Coronary; Coronary Arteriosclerosis; Coronary artery; Databases; Development; Devices; Disease; Doctor of Philosophy; Electrical Engineering; Electrocoagulation; Elements; Engineering; Ensure; Event; Failure; Fluoroscopy; Health; Health Services Accessibility; Hospitals; Individual; Infection prevention; Inflammatory; Intervention; Left Ventricular Function; Lower Extremity; Magnetism; Mechanics; Medical; Mental Depression; Minnesota; Modeling; Morbidity - disease rate; Myocardial Infarction; North America; Patient Care; Patients; Peripheral; Peripheral arterial disease; Persons; Phase; Procedures; Research; Resources; Risk; Safety; Specific qualifier value; Speed; Stenosis; Stents; Stroke; System; Techniques; Time; Tissues; Torque; United States; Vascular Diseases; Woman; acute coronary syndrome; artery occlusion; cerebrovascular; claudication; critical limb Ischemia; design; ferrite; improved; innovation; instrumentation; limb ischemia; limb loss; magnetic field; medical schools; mortality; new technology; novel; novel strategies; prototype; reduce symptoms; research and development; success

Project Summary/Abstract We propose to develop an innovative wiring catheter system to reliably direct subintimal crossing and re-entry into the artery true lumen during treatment of complex arterial chronic total occlusions (CTO). The proposed system will improve techniques for treating complex CTOs during percutaneous coronary and peripheral artery interventions (PCI). Atherosclerosis drives development of coronary artery, cerebrovascular, and peripheral arterial disease. Improved CTO crossing devices and techniques will allow more operators to perform these procedures and improve patient care. The proposed project investigates key elements of a novel guided re-entry catheter system to be used in a rendezvous maneuver to increase the precision, speed, reliability, and safety of retrograde CTO PCI crossing. A prototype device will be developed and evaluated.

项目概要/摘要 我们建议开发一种创新的布线导管系统，以可靠地引导内膜下穿过和重新进入 在治疗复杂动脉慢性完全闭塞 (CTO) 期间进入动脉真腔。拟议的 系统将改进经皮冠状动脉和外周动脉治疗复杂 CTO 的技术 干预措施（PCI）。动脉粥样硬化驱动冠状动脉、脑血管和外周血管的发育 动脉疾病。改进的 CTO 交叉设备和技术将使更多操作员能够执行这些操作 程序并改善患者护理。拟议项目研究新型引导再入的关键要素 用于交会机动的导管系统，以提高交会机动的精度、速度、可靠性和安全性 逆行CTO PCI 穿越。将开发和评估原型设备。