Mississippi Center for Clinical and Translational Research

密西西比临床和转化研究中心

• 批准号: 10472628
• 负责人: Joey P. Granger
• 金额: $ 399.55万
• 依托单位: UNIVERSITY OF MISSISSIPPI MED CTR
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-08-18 至 2026-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10472628
• 关键词: Academic Medical Centers; Address; Adult; Advisory Committees; African American population; Alabama; Americas; Area; Behavior Therapy; Biomedical Research; Biometry; Black race; Cardiometabolic Disease; Cardiovascular Diseases; Cause of Death; Center for Translational Science Activities; Cessation of life; Child; Clinic; Clinical; Clinical Research; Clinical Sciences; Cohort Studies; Collaborations; Communicable Diseases; Communication; Communities; Community Outreach; Data Collection; Development; Diabetes Mellitus; Diagnosis; Disease; Economically Deprived Population; Effectiveness; Epidemiology; Evaluation; Extramural Activities; Faculty; Fostering; Foundations; Funding; Goals; Growth; Health; Health Disparities Research; Health Personnel; Health Services Accessibility; Human Resources; Income; Infant Mortality; Infrastructure; Institutes; Institution; Interdisciplinary Study; Lead; Leadership; Louisiana; Low Birth Weight Infant; Marketing; Medical center; Mentors; Mentorship; Mississippi; Modernization; National Institute of General Medical Sciences; Obesity; Obesity associated disease; Office of Administrative Management; Outcome; Outreach Research; Performance; Persons; Phase; Pilot Projects; Population; Population Research; Poverty; Research; Research Design; Research Personnel; Research Project Grants; Research Support; Resources; Rural; Rural Community; Rural Health; Scientist; Services; Statistical Data Interpretation; Structure; Telemedicine; Time; Training; Training Support; Translational Research; Universities; Urban Community; Ursidae Family; Work; cardiometabolism; clinical care; clinical center; clinical implementation; college; community engaged research; community engagement; data management; data warehouse; electronic data; epidemiology study; ethnic health disparity; health disparity; implementation research; implementation science; improved; innovation; member; multidisciplinary; outreach; physical inactivity; practice-based research network; programs; racial and ethnic; racial disparity; recruit; rural health disparities; statistics; success; telehealth; tool; training opportunity; translational engagement; translational research program; Academic Medical Centers; Address; Adult; Advisory Committees; African American population; Alabama; Americas; Area; Behavior Therapy; Biomedical Research; Biometry; Black race; Cardiometabolic Disease; Cardiovascular Diseases; Cause of Death; Center for Translational Science Activities; Cessation of life; Child; Clinic; Clinical; Clinical Research; Clinical Sciences; Cohort Studies; Collaborations; Communicable Diseases; Communication; Communities; Community Outreach; Data Collection; Development; Diabetes Mellitus; Diagnosis; Disease; Economically Deprived Population; Effectiveness; Epidemiology; Evaluation; Extramural Activities; Faculty; Fostering; Foundations; Funding; Goals; Growth; Health; Health Disparities Research; Health Personnel; Health Services Accessibility; Human Resources; Income; Infant Mortality; Infrastructure; Institutes; Institution; Interdisciplinary Study; Lead; Leadership; Louisiana; Low Birth Weight Infant; Marketing; Medical center; Mentors; Mentorship; Mississippi; Modernization; National Institute of General Medical Sciences; Obesity; Obesity associated disease; Office of Administrative Management; Outcome; Outreach Research; Performance; Persons; Phase; Pilot Projects; Population; Population Research; Poverty; Research; Research Design; Research Personnel; Research Project Grants; Research Support; Resources; Rural; Rural Community; Rural Health; Scientist; Services; Statistical Data Interpretation; Structure; Telemedicine; Time; Training; Training Support; Translational Research; Universities; Urban Community; Ursidae Family; Work; cardiometabolism; clinical care; clinical center; clinical implementation; college; community engaged research; community engagement; data management; data warehouse; electronic data; epidemiology study; ethnic health disparity; health disparity; implementation research; implementation science; improved; innovation; member; multidisciplinary; outreach; physical inactivity; practice-based research network; programs; racial and ethnic; racial disparity; recruit; rural health disparities; statistics; success; telehealth; tool; training opportunity; translational engagement; translational research program

PROJECT SUMMARY. Mississippi has some of the nation's worst health outcomes and was ranked by the United Health Foundation as the “least healthy state” in 2019. Further, the racial disparities surrounding these health outcomes are profound. The complexities associated with effectively addressing Mississippians' health outcomes and ameliorating Mississippi's health disparities necessitate a strong, multi-disciplinary research and outreach infrastructure. The Mississippi Center for Clinical and Translational Research (MCCTR) was established in 2016 to provide this infrastructure, equipping researchers with the resources needed to conduct clinical, translational, and population-based research projects. The MCCTR proposes to continue and expand its efforts through what it has termed as “Phase II.” In Phase II, the MCCTR will add two new institutional partners, Mississippi State University and University of Mississippi-Oxford, to its Phase I partners, University of Mississippi Medical Center, Tougaloo College, and University of Southern Mississippi. It will also add two CTR/CTSAs as collaborating partners, the University of Alabama at Birmingham's Center for Clinical and Translational Science and the Northwestern University Clinical and Translational Sciences, to its Phase I partners: Mayo Clinic's Center for Clinical and Translational Science and the Louisiana Clinical and Translational Science Center. The Administrative Core will be responsible for managing the administrative, fiscal, and scientific aspects of the MCCTR, including the oversight, marketing, and coordination of all MCCTR cores and activities. The Professional Development Core will offer structured mentorship, training opportunities, and protected research time for early stage investigators at MCCTR partner institutions. The Community Engagement and Outreach Core will provide training and support to investigators in conducting community engaged research; partner with healthcare providers through its new Practice-Based Research Network; and work with its expanded Community Advisory Board to provide bi-directional communication and guidance on community values, concerns, and needs and represent the MCCTR to Mississippi Communities. The Biostatistics, Epidemiology, and Research Design Core will provide training and assistance with research design, data collection and management, and statistical analysis to increase the effectiveness, efficiency, and success of research conducted by MCCTR investigators. The Pilot Projects Program will support clinical, translational, and population-based research projects likely to have a meaningful impact on Mississippi health outcomes and lead to extramural funding. The Research Services Core will support research projects through study coordination and regulatory support and will help connect researchers to communities through expanded telehealth and cohort-study resources. Finally, the Tracking and Evaluation Core will provide accurate and timely information on MCCTR performance and impact to inform planning and implementation by leadership and advisory bodies. Through the infrastructure of resources and personnel developed by MCCTR, Mississippi's health outcomes will be positively impacted.

项目摘要。密西西比州有一些美国最糟糕的健康成果，并被 联合卫生基金会是2019年的“最不健康状态”。此外，围绕这些国家的种族分布 健康结果是深刻的。与有效解决密西西比州健康有关的复杂性 成果和改善密西西比州的健康差异必须进行强大的多学科研究和 外展基础设施。密西西比州临床和转化研究中心（MCCTR）是 成立于2016年，旨在提供此基础设施，为研究人员提供了进行所需的资源 临床，转化和基于人群的研究项目。 MCCTR的提议继续并扩展 它通过称为“第二阶段”的努力。在第二阶段，MCCTR将增加两个新的机构合作伙伴， 密西西比州立大学和密西西比州大学的I阶段合作伙伴，密西西比大学 医学中心，据塔加卢学院和南密西西比大学。它还将添加两个ctr/ctsas 伯明翰临床与转化科学中心阿拉巴马大学合作合作伙伴合作 以及西北大学的临床和翻译科学，到I期合作伙伴：梅奥诊所中心 用于临床和转化科学以及路易斯安那州临床和转化科学中心。 行政核心将负责管理管理，财政和科学方面 MCCTR，包括对所有MCCTR核心和活动的监督，营销和协调。这 专业发展核心将提供结构化的心态，培训机会和受保护的研究 MCCTR合作伙伴机构的早期调查人员的时间。社区参与和宣传 核心将为调查人员提供培训和支持，以进行社区参与研究；与之合作 医疗保健提供者通过其新的基于实践的研究网络；并与扩展的社区合作 咨询委员会提供双向交流和有关社区价值观，关注和的指导 需要并代表密西西比州社区的MCCTR。生物统计学，流行病学和研究 设计核心将在研究设计，数据收集和管理以及 统计分析以提高MCCTR进行的研究的有效性，效率和成功 调查人员。试点项目计划将支持临床，转化和基于人群的研究 项目可能会对密西西比州的健康成果产生有意义的影响，并导致壁外资金。这 研究服务核心将通过研究协调和监管支持来支持研究项目， 将通过扩展的远程医疗和同伙研究资源来帮助研究人员将研究人员与社区联系起来。最后， 跟踪和评估核心将提供有关MCCTR性能和及时的及时信息 影响领导和咨询机构的计划和实施的影响。通过基础设施 密西西比州的健康成果由MCCTR开发的资源和人员将受到积极影响。