Administrative Core

行政核心

• 批准号: 10469446
• 负责人: ROBERT J VASSAR
• 金额: $ 57.06万
• 依托单位: NORTHWESTERN UNIVERSITY AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-08-15 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10469446
• 关键词: Adopted; Adoption; Advocate; Alzheimer' s Disease; Animal Welfare; Biological Markers; Caregivers; Chicago; Cities; Clinical Trials; Collaborations; Contracts; Data; Dementia; Development; Education; Ensure; Faculty; Funding; Goals; Health Insurance Portability and Accountability Act; Illinois; Institutional Review Boards; Lead; Leadership; Monitor; Parents; Patients; Policies; Progress Reports; Research; Research Priority; Resource Sharing; Resources; Role; Running; Sampling; Time; Translational Research; United States National Institutes of Health; Universities; Update; beneficiary; cohesion; human subject; innovation; meetings; molecular imaging; operation; ranpirnase; recruit; responsible research conduct

PROJECT SUMMARY - ADMINISTRATIVE CORE The ultimate goal of an Alzheimer's Disease Research Center (ADRC) is to promote innovative research on dementia and its treatments while ensuring that patients and caregivers become the beneficiaries of resultant advances. An effective Administrative Core is essential for transforming these goals into accomplishments. To this end, the Administrative Core of the Northwestern ADRC will be guided by the following goals: 1) Lead the day-to-day running of the ADRC and promote "centerness" so that ADRC components function cohesively and leverage dementia-related activities throughout Northwestern University. 2) Maximize the utilization of ADRC resources to fit local and national priorities. 3) Coordinate the adoption of UDS-3, the FTLD module, new clinical trials, and the increased emphasis on biomarkers, including structural and molecular imaging. 4) Facilitate interactions with NACC, NCRAD, and national consortia such as ADNI and ADCS, the Alzheimer's Association, and relevant agencies within the City of Chicago and State of Illinois. 5) Encourage innovative Development Projects, coordinate their review, and monitor the progress of those that receive ADRC funding. To fulfill these goals, the Administrative Core will oversee the finances of the parent NIA P30 and of additional contracts related to multi-center collaborations and clinical trials. It will be responsible for timely progress reports related to these activities as well as the organization of the yearly Scientific Advisory Board (SAB) meeting. An equally important role will be to ensure that the ADRC as a whole meets all IRB and HIPAA requirements and that it is in compliance with NIH policies for human subjects, animal welfare, scientific integrity, data and sample sharing and financial policy. The Administrative Core is also responsible for coordinating the interactions of the ADRC with NIA, other NIH components, other ADRCs, and relevant agencies at the national, state and local levels. Within Northwestern University, the Administrative Core will advocate the allocation of additional faculty, space and financial resources to dementia research.

项目摘要 - 行政核心 阿尔茨海默氏病研究中心（ADRC）的最终目标是促进有关有关的创新研究 痴呆症及其治疗方法，同时确保患者和看护者成为受益人 进步。有效的行政核心对于将这些目标转变为成就至关重要。到 这一目标是西北ADRC的行政核心将受到以下目标的指导： 1）领导ADRC的日常运行并促进“中心度”，以便ADRC组件功能 整个西北大学都有内凝并且利用与痴呆相关的活动。 2）最大化ADRC资源以适合本地和国家优先事项的利用。 3）协调UDS-3，FTLD模块，新临床试验的采用以及对越来越重视 生物标志物，包括结构和分子成像。 4）促进与NACC，NCRAD和国家财团的互动，例如ADNI和ADC， 阿尔茨海默氏症协会以及芝加哥市和伊利诺伊州内的相关机构。 5）鼓励创新的开发项目，协调其审查并监视这些项目的进度 收到ADRC资金。 为了实现这些目标，行政核心将监督家长NIA P30的财务状况和其他 与多中心协作和临床试验有关的合同。它将负责及时的进步 与这些活动以及年度科学咨询委员会（SAB）的组织有关的报告 会议。同样重要的角色将是确保ADRC整体符合所有IRB和HIPAA 要求，它符合人类受试者的NIH政策，动物福利，科学 诚信，数据和样本共享和财务政策。行政核心也负责 协调ADRC与NIA，其他NIH组件，其他ADRC和相关的相互作用 国家，州和地方一级的机构。在西北大学，行政核心将 主张将其他教职员工，空间和财务资源分配给痴呆症研究。