31st Meeting of the American Society for Rickettsiology

美国立克次体学会第31次会议

• 批准号: 10469039
• 负责人: Kevin R. Macaluso
• 金额: $ 0.8万
• 依托单位: UNIVERSITY OF SOUTH ALABAMA
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-06-23 至 2023-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10469039
• 关键词: Academia; Address; Administrator; Admission activity; Affect; American; Animal Model; Antibiotics; Arthropod Vectors; Arthropods; Award; Bacteria; Basic Science; Biological; Biology; Cells; Cellular biology; Cessation of life; Child Care; Clinical Medicine; Committee Members; Congresses; Development; Diagnostic; Discipline; Disease; Doxycycline; Epidemiology; Feces; Fleas; Fostering; Genetic; Genome; Genomics; Goals; Government; Grant; Group Meetings; Health; Hospitalization; Human; Immune response; Immunization; Immunology; Industry; Interdisciplinary Study; Investigation; Knowledge; Laboratories; Lice; Life Style; Location; Lyme Disease; Metabolism; Mites; Modeling; Molecular; Molecular Biology; Morbidity - disease rate; Nature; Oral; Organism; Participant; Pathogenesis; Pathogenicity; Pattern; Pharmaceutical Preparations; Physiology; Play; Population; Prevalence; Process; Production; Public Health; Recording of previous events; Reporting; Research; Research Personnel; Rickettsia; Rickettsia Infections; Role; Science; Scientist; Site; Societies; Testing; Therapeutic; Tick-Borne Diseases; Translating; Travel; Underrepresented Populations; United States; Vaccines; Variant; Visual; arthropod-borne; burden of illness; career; clinical diagnosis; comparative; cost; disability; feeding; fitness; genetic manipulation; immunoreaction; improved; innovation; interest; lectures; meetings; member; mortality; neglect; novel; pathogen; pathogenic bacteria; posters; programs; recruit; saliva secretion; service programs; symbiont; symposium; tick-borne; vector; vector tick; vector-borne; working group

Meeting Summary: 31st Meeting of the American Society for Rickettsiology Rickettsial diseases are significant domestic and global causes of morbidity and death. In the United States, tick- borne rickettsial infections are responsible a majority of hospital admissions, ICU admissions, and fatalities. Many new Rickettsia and related species are recognized globally for their increase in prevalence and nearly all are neglected. The absence of an approved vaccine for humans, combined with insufficient laboratory diagnostics and challenging clinical diagnosis, suggest a public health need to examine the biology of rickettsiae. It is now realized that these obligate intracellular bacteria can vary from highly pathogenic to, in some cases, essential mutualistic organisms in arthropod vectors. Fundamental investigations into the differences in rickettsial interactions between vertebrate hosts and arthropod vectors are needed to address critical knowledge gaps. Research into the mechanisms that drive the biological interaction between Rickettsia and hosts in congruent with the Tick-Borne Disease Working Group report to Congress. This report emphasizes that understanding the factors contributing to Rickettsia’s ability to cause disease, would drive innovation and novel countermeasure development. The American Society for Rickettsiology (ASR) has a long history of organizing meetings that foster scientific interactions and intellectual exchange among experts on rickettsial diseases. The 31st Meeting of the ASR will be held June 25-28, 2022 in Greenville, SC, a central venue that will facilitate scientists, investigators and clinicians to gather, exchange ideas, and information, and to establish new multidisciplinary collaborations. Approximately 200 attendees representing early stage investigators, established scientists, and clinicians from academia, government, and industry are anticipated to attend. The conference’s overarching goal is to advance knowledge and stimulate interactions through oral presentations and poster sessions with audience-interactive and networking opportunities. To address the knowledge gaps, we propose a theme for the meeting entitled, “Advances in the Biological and Molecular Mechanisms of Rickettsial Pathogenesis.” The meeting’s aims are to (i) promote scientific exchange among participants through lectures and short talks; (ii) encourage participation by early career investigators and those underrepresented in the biomedical sciences through travel grants, research presentation opportunities, and by involvement in significant meeting organization roles; (iii) present cutting-edge research of diseases caused by arthropod-borne/obligate intracellular pathogens; and, (iv) foster intellectual exchange and networking between early career and established investigators. Participants’ child care needs and disability access will also be addressed. Support for travel awards for early career investigators and trainees from underrepresented groups, cost of coordination, and for audio-visual services and program production is requested.

会议摘要：美国立克次体学会第31届会议 立克次体疾病是美国国内和全球发病和死亡的重要原因。 立克次体感染是造成大多数入院、重症监护病房和死亡的原因。 许多新的立克次体和相关物种因其流行率的增加而得到全球认可，并且几乎所有 由于缺乏经批准的人类疫苗，加上实验室不足，这些问题都被忽视了。 诊断和具有挑战性的临床诊断表明公共卫生需要检查立克次体的生物学。 现在人们认识到，这些专性细胞内细菌的致病性可能很高，在某些情况下， 节肢动物媒介中重要的互利生物体差异的基础研究。 需要脊椎动物宿主和节肢动物媒介之间的相互作用来解决关键的知识差距。 研究驱动立克次体与宿主之间生物相互作用的机制 蜱传疾病工作组向国会提交的报告强调了对蜱传疾病的了解。 导致立克次体致病能力的因素将推动创新和新颖的对策 美国立克次体学会（ASR）在组织会议方面有着悠久的历史。 促进立克次体病专家之间的科学互动和知识交流 第31次会议。 ASR 会议将于 2022 年 6 月 25 日至 28 日在南卡罗来纳州格林维尔举行，这是一个为科学家提供便利的中心场所， 研究人员和人员收集、交流想法和信息，并建立新的多学科 约 200 名与会者代表早期研究人员、知名科学家和 会议的总体目标 是通过口头演讲和海报会议来增进知识并刺激互动 为了解决知识差距，我们提出了一个主题。 会议题为“立克次体发病机制的生物和分子机制的进展”。 会议的目的是（i）通过讲座和简短的谈话促进参与者之间的科学交流； 鼓励早期职业研究人员和生物医学领域代表性不足的人员参与 通过旅费补助、研究报告机会以及参与重要会议组织 作用；(iii) 介绍节肢动物传播/专性细胞内病原体引起的疾病的前沿研究； (iv) 促进早期职业研究者和成熟研究者之间的知识交流和联系。 参与者的儿童保育需求和残疾人通道也将得到解决，为早期旅行奖励提供支持。 来自代表性不足群体的职业调查员和受训人员、协调成本以及视听成本 需要服务和节目制作。