STROKENET REGIONAL COORDINATING CENTER Georgia StrokeNet

STROKENET 区域协调中心佐治亚州 StrokeNet

基本信息

批准号：
10457481
负责人：
MICHAEL Ross FRANKEL
金额：
$ 30.47万
依托单位：
EMORY UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2018
资助国家：
美国
起止时间：
2018-09-01 至 2023-12-19
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10457481
关键词：
Accident and Emergency department Acute Agreement Caring Clinical Clinical Research Clinical Sciences Clinical Trials Clinical Trials Network Collaborations Communities Data Detection Discipline Disease Early treatment Emergency Care Emergency Medicine Enrollment Evidence based practice Funding Goals Hospitals Hour Individual Industry Infrastructure Institutes Institutional Review Boards Intervention Interview Investigation Joints Leadership Link Master of Public Health Master of Science Medical Medicine Methods Mission Multi-Institutional Clinical Trial National Institute of Neurological Disorders and Stroke Neurologic Neurological emergencies Neurology Neurosciences Research Outreach Research Patients Pediatrics Peer Review Persons Pharmacy Ethics Protocols documentation Public Health Randomized Clinical Trials Recording of previous events Recovery Recurrence Registries Rehabilitation therapy Research Research Assistant Research Personnel Research Subject Recruitments Research Subjects Research Training Resources Risk Scientist Site Source Stroke Stroke prevention StrokeNet clinical trials StrokeNet trials System Translating Translational Research United States National Institutes of Health Work acute stroke base career clinical practice data management data sharing design effective therapy evidence base experience faculty mentor improved innovation interest member neurosurgery participant enrollment patient registry patient screening pre-clinical programs recruit screening skills stroke clinical trials stroke rehabilitation success synergism telestroke training opportunity treatment trial working group

Accident and Emergency department Acute Agreement Caring Clinical Clinical Research Clinical Sciences Clinical Trials Clinical Trials Network Collaborations Communities Data Detection Discipline Disease Early treatment Emergency Care Emergency Medicine Enrollment Evidence based practice Funding Goals Hospitals Hour Individual Industry Infrastructure Institutes Institutional Review Boards Intervention Interview Investigation Joints Leadership Link Master of Public Health Master of Science Medical Medicine Methods Mission Multi-Institutional Clinical Trial National Institute of Neurological Disorders and Stroke Neurologic Neurological emergencies Neurology Neurosciences Research Outreach Research Patients Pediatrics Peer Review Persons Pharmacy Ethics Protocols documentation Public Health Randomized Clinical Trials Recording of previous events Recovery Recurrence Registries Rehabilitation therapy Research Research Assistant Research Personnel Research Subject Recruitments Research Subjects Research Training Resources Risk Scientist Site Source Stroke Stroke prevention StrokeNet clinical trials StrokeNet trials System Translating Translational Research United States National Institutes of Health Work acute stroke base career clinical practice data management data sharing design effective therapy evidence base experience faculty mentor improved innovation interest member neurosurgery participant enrollment patient registry patient screening pre-clinical programs recruit screening skills stroke clinical trials stroke rehabilitation success synergism telestroke training opportunity treatment trial working group

展开

项目摘要

The Specific Aims of this proposal are to: : 1) enhance the successful mission of the Georgia StrokeNet by accelerating recruitment into NIH StrokeNet clinical trials for patients with acute stroke, people at risk for recurrent stroke and individuals recovering from stroke; 2) develop and propose new and innovative clinical trials in stroke to be conducted within the NIH StrokeNet; and 3) enhance the training opportunities for promising young investigators interested in clinical stroke research as a career. As a currently-funded NIH StrokeNet Regional Coordinating Center (RCC), the Georgia StrokeNet brings an established infrastructure of highly successful and collaborative investigators and coordinators, with many years of proven expertise in designing, conducting, and enrolling patients into randomized clinical trials across the continuum of stroke care, from pre-hospital through rehabilitation. Our RCC has demonstrated the ability to quickly implement research protocols using master trial agreements and a central IRB, and has brought to the existing network strong leadership skills, as evidenced by our team members’ active and ongoing participation in NIH StrokeNet working groups including Co-Chair of the NIH StrokeNet’s Rehabilitation working group and the only Project Coordinator representation in the Acute Stroke Working Group since implementation. Emory’s Georgia StrokeNet proposal builds upon our RCC’s track record of 5 years of highly successful participation as an NIH StrokeNet site, 10 years as a top enroller for the NINDS-sponsored Neurological Treatment Trials Network (NETT), recent selection as one of only 11 hubs for the NIH-funded SIREN (Strategies to Innovate EmeRgENcy Care) Clinical Trials Network, and a 25 year history of high enrollment in multiple NIH and industry sponsored practice changing randomized clinical trials in stroke.

该提案的具体目的是：：1）增强佐治亚州街道的成功使命。加速招募急性中风患者的NIH Strokenet临床试验，患有风险的人对于复发性中风和中风恢复的个人； 2）开发和提议新的和创新的在NIH Strokenet内进行中风的临床试验； 3）增强培训有前途对临床中风研究感兴趣的年轻调查人员的机会。作为当前资助的NIH Strokenet区域协调中心（RCC），乔治亚州Strokenet带来了建立了非常成功和合作的调查员和协调员的基础设施，多年来在设计，进行和招募患者进行随机临床试验方面的经验丰富的专业知识中风护理的连续性，从院前到康复。我们的RCC已经证明了快速使用大师试验协议和中央IRB实施研究协议，并带给了现有网络强大的领导能力，我们团队成员的积极和持续的参与证明了在NIH Strokenet工作组中，包括NIH Strokenet的康复工作组和自实施以来，急性中风工作组中唯一的项目协调员表示。埃默里的佐治亚州Strokenet提案以我们的RCC的5年非常成功参与的往绩为基础 NIH Strokenet网站，10年，作为NINDS赞助神经治疗试验的最高注册者 Network（Nett），最近作为NIH资助的Siren仅有的11个枢纽之一（创新的策略紧急护理）临床试验网络，以及在多个NIH和行业中招收高25年的历史赞助实践改变了中风的随机临床试验。