Academic Leadership Award for Statistical Training in Multidisciplinary Aging Research

多学科老龄化研究统计培训学术领导奖

• 批准号: 10427564
• 负责人: SUJUAN GAO
• 金额: $ 15.79万
• 依托单位: INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-08-15 至 2027-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10427564
• 关键词: Address; Adult; Age; Aging; Alzheimer' s Disease; Alzheimer' s disease related dementia; Archives; Award; Biological Markers; Biometry; Blood; Cardiovascular Diseases; Case Study; Clinical Data; Computerized Medical Record; Data; Data Analyses; Data Analytics; Data Collection; Data Science; Development; Dimensions; Disease; Doctor of Philosophy; Educational Curriculum; Epidemiology; Faculty; Funding; Genomics; Goals; Grant; Growth; Health; Impaired cognition; Indiana; Individual; Intensive Care Units; K-Series Research Career Programs; Leadership; Longitudinal Studies; Malignant Neoplasms; Mentors; Modernization; Musculoskeletal; Nature; Neurosciences; Pharmacy facility; Physicians; Pilot Projects; Population; Postdoctoral Fellow; Prevalence; Principal Investigator; Productivity; Public Health; Quality of life; Recovery; Reproducibility; Research; Research Design; Research Infrastructure; Research Methodology; Research Personnel; Research Project Grants; Resources; Scientist; Statistical Methods; Students; Survivors; Training; Training Activity; Training Programs; United States National Institutes of Health; Universities; age related; aging population; analytical tool; career; comorbidity; data management; data resource; digital; disability; doctoral student; epidemiology study; genetic epidemiology; health data; high dimensionality; imaging facilities; interdisciplinary approach; lectures; medical schools; multidisciplinary; multiple omics; neuroimaging; next generation; programs; research study; statistics

Abstract Aging research studies are increasingly multidisciplinary in nature with longitudinal study design and extensive data collection including genomic, multi-omics, and large electronic medical records data in addition to traditional clinical data. These increased complexities in study design and data dimensionality present special challenges to aging researchers in data analyses and result interpretation for meaningful and reproducible scientific discoveries. I have conducted independent statistical research and have also collaborated extensively with investigators in aging research during my two-decades career at Indiana University School of Medicine. I have also mentored junior investigators on K-applications and directed Ph.D. students in research focused on statistical methods in aging research. The Academic Leadership Award will provide support for developing a comprehensive statistical training program that includes advanced statistical methods tailored to physicians and scientists in aging research and illustrated using case studies from aging research projects. The first aim is to develop an Advanced Statistical Methods in Aging Research curriculum that will provide comprehensive, in-depth training of modern statistical methods applicable to aging research. The second aim is to enhance research capacity at Indiana University by providing data resources and analytical tools from completed and ongoing aging studies to support secondary data analyses and pilot projects. The third aim is to provide individual mentoring to junior investigators for obtaining career development awards. A comprehensive, robust and advanced statistical training program will lead to better study design, increased research productivity, higher research quality and reproducible scientific discoveries in aging research.

抽象的 纵向研究设计本质上，衰老研究的研究越来越多学科， 广泛的数据收集，包括基因组，多媒体和大型电子病历数据 附加传统临床数据。这些研究设计和数据维度的复杂性增加 在数据分析中对老龄化研究人员面临特殊挑战，并为有意义的结果解释 和可再现的科学发现。我进行了独立的统计研究，也 在我在印第安纳州的两个十年职业生涯中，与研究人员进行了广泛的合作 大学医学院。我还指导了初级调查员K-申请并指导 博士研究的学生重点介绍了衰老研究的统计方法。学术领导 奖项将为制定全面的统计培训计划提供支持，其中包括 针对老化研究的医师和科学家量身定制的先进统计方法，并使用 老化研究项目的案例研究。第一个目的是开发一种先进的统计方法 老化的研究课程将提供现代统计的全面，深入的培训 适用于衰老研究的方法。第二个目的是提高印第安纳州的研究能力 通过提供数据资源和分析工具，从完成和正在进行的衰老研究到 支持二级数据分析和试点项目。第三个目的是向个人指导 初级调查人员获得了职业发展奖。全面，健壮和高级 统计培训计划将导致更好的研究设计，提高研究生产率，更高 衰老研究中的研究质量和可重复的科学发现。