Academic Leadership Award for Statistical Training in Multidisciplinary Aging Research

多学科老龄化研究统计培训学术领导奖

• 批准号: 10427564
• 负责人: SUJUAN GAO
• 金额: $ 15.79万
• 依托单位: INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-08-15 至 2027-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10427564
• 关键词: Address; Adult; Age; Aging; Alzheimer' s Disease; Alzheimer' s disease related dementia; Archives; Award; Biological Markers; Biometry; Blood; Cardiovascular Diseases; Case Study; Clinical Data; Computerized Medical Record; Data; Data Analyses; Data Analytics; Data Collection; Data Science; Development; Dimensions; Disease; Doctor of Philosophy; Educational Curriculum; Epidemiology; Faculty; Funding; Genomics; Goals; Grant; Growth; Health; Impaired cognition; Indiana; Individual; Intensive Care Units; K-Series Research Career Programs; Leadership; Longitudinal Studies; Malignant Neoplasms; Mentors; Modernization; Musculoskeletal; Nature; Neurosciences; Pharmacy facility; Physicians; Pilot Projects; Population; Postdoctoral Fellow; Prevalence; Principal Investigator; Productivity; Public Health; Quality of life; Recovery; Reproducibility; Research; Research Design; Research Infrastructure; Research Methodology; Research Personnel; Research Project Grants; Resources; Scientist; Statistical Methods; Students; Survivors; Training; Training Activity; Training Programs; United States National Institutes of Health; Universities; age related; aging population; analytical tool; career; comorbidity; data management; data resource; digital; disability; doctoral student; epidemiology study; genetic epidemiology; health data; high dimensionality; imaging facilities; interdisciplinary approach; lectures; medical schools; multidisciplinary; multiple omics; neuroimaging; next generation; programs; research study; statistics

Abstract Aging research studies are increasingly multidisciplinary in nature with longitudinal study design and extensive data collection including genomic, multi-omics, and large electronic medical records data in addition to traditional clinical data. These increased complexities in study design and data dimensionality present special challenges to aging researchers in data analyses and result interpretation for meaningful and reproducible scientific discoveries. I have conducted independent statistical research and have also collaborated extensively with investigators in aging research during my two-decades career at Indiana University School of Medicine. I have also mentored junior investigators on K-applications and directed Ph.D. students in research focused on statistical methods in aging research. The Academic Leadership Award will provide support for developing a comprehensive statistical training program that includes advanced statistical methods tailored to physicians and scientists in aging research and illustrated using case studies from aging research projects. The first aim is to develop an Advanced Statistical Methods in Aging Research curriculum that will provide comprehensive, in-depth training of modern statistical methods applicable to aging research. The second aim is to enhance research capacity at Indiana University by providing data resources and analytical tools from completed and ongoing aging studies to support secondary data analyses and pilot projects. The third aim is to provide individual mentoring to junior investigators for obtaining career development awards. A comprehensive, robust and advanced statistical training program will lead to better study design, increased research productivity, higher research quality and reproducible scientific discoveries in aging research.

抽象的 老龄化研究本质上越来越多学科，具有纵向研究设计和 广泛的数据收集，包括基因组、多组学和大型电子病历数据 除了传统的临床数据。这些增加了研究设计和数据维度的复杂性 为老年研究人员在数据分析和结果解释方面提出了特殊的挑战，以获得有意义的结果 和可重复的科学发现。我进行了独立的统计研究，并且还 在印第安纳州的两年职业生涯中，我与衰老研究领域的研究人员进行了广泛的合作 大学医学院。我还指导初级研究人员进行 K 申请并指导 博士学生的研究重点是衰老研究中的统计方法。学术领导 该奖项将为制定全面的统计培训计划提供支持，其中包括 为衰老研究中的医生和科学家量身定制的先进统计方法，并使用说明 老龄化研究项目的案例研究。第一个目标是开发一种先进的统计方法 老龄化研究课程将提供全面、深入的现代统计培训 适用于衰老研究的方法。第二个目标是提高印第安纳州的研究能力 大学通过提供已完成和正在进行的老龄化研究的数据资源和分析工具， 支持二次数据分析和试点项目。第三个目标是提供个人指导 初级研究员获得职业发展奖。全面、稳健、先进 统计培训计划将带来更好的研究设计、提高研究生产力、 衰老研究中的研究质量和可重复的科学发现。