Research Methods in Pediatric Cardiovascular Disease

小儿心血管疾病的研究方法

• 批准号: 10421264
• 负责人: Sarah D DE FERRANTI
• 金额: $ 50.56万
• 依托单位: BOSTON CHILDREN'S HOSPITAL
• 依托单位国家: 美国
• 财政年份: 1983
• 资助国家: 美国
• 起止时间: 1983-01-01 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10421264
• 关键词: Cardiovascular Diseases; Childhood; Research Methodology

ABSTRACT The goal of the Research Training Program in Pediatric Cardiovascular Disease is to attract and train highly qualified MD, MD-PhD, and PhD scientists dedicated to advancing the understanding, diagnosis, treatment, and prevention of pediatric and congenital heart disease. The program is based in the Department of Cardiology at Boston Children’s Hospital (BCH), a leading national and international center for pediatric cardiology and treatment of congenital heart disease. The 34 Faculty Mentors in this T32 include outstanding and highly collaborative scientists - drawn from BCH, Harvard Medical School (HMS) and its affiliated hospitals, and MIT - with expertise in basic, translational, and clinical research relevant to pediatric cardiovascular disease. Together, they hold $34.9M in total support for the current year. Of those supported in the past 15 years, 91% remain active in research, 76% continue in academia, and 18% are from under- represented groups. A Research Training Executive Committee (RTEC), comprising the Program Directors and four current mentors, will oversee the progress of fellow training, career development, and mentoring, approve new mentors, and ensure that existing mentors meet the metrics of the training program. We are requesting 8 trainee positions, on average supporting the training of 4 with MD or MD-PhD degrees and 4 with PhD degrees each year. Entry into the T32 training program is highly competitive – from our highly talented candidate pool, ~7% are selected for T32 support. We will expose trainees to the clinical, translational, or basic research techniques that represent the current state of the art. A Core Curriculum will include training in biostatistics, Work-in-Progress meetings, a cardiovascular seminar series, a hands-on didactic series in cardiac anatomy, and career development seminars. Trainees will also participate in an annual retreat and regular meetings attended by T32 trainees and mentors. Through these interchanges, clinically-oriented trainees will gain understanding of fundamental cardiovascular biology, and basic science trainees will gain understanding of important clinical problems. The program allows trainees to further tailor their training to specific research interests by taking advantage of the stellar opportunities for formal coursework and the myriad of scientific seminars and lectures at BCH, HMS, the Harvard School of Public Health, and MIT. We also teach trainees the importance of teamwork, the clear communication of research findings, responsible conduct of human and laboratory research, and mentoring skills. Milestones and metrics for trainee progress and the training program itself are outlined and will be overseen by the RTEC. Considerable institutional support includes supplementation of trainee stipends and travel funds, and support for the EAC and program activities. Excellent training in rigorous experimental bench research and in translational and clinical investigation within an interactive and vibrant program will prepare graduates to become leaders in pediatric cardiology and cardiovascular research.

抽象的 小儿心血管疾病研究培训计划的目标是高度吸引和训练 合格的MD，MD-PHD和博士学位科学家致力于促进理解，诊断，治疗， 以及预防小儿和先天性心脏病。该计划位于部门 波士顿儿童医院（BCH）的心脏病学，小儿国家和国际领先的中心 先天性心脏病的心脏病学和治疗。 T32中的34位教师导师包括出色 以及高度合作的科学家 - 来自BCH，哈佛医学院（HMS）及其分支机构 医院和麻省理工学院 - 具有与儿科有关的基本，翻译和临床研究的专业知识 心血管疾病。他们共同持有3490万美元的全部支持。那些支持 在过去的15年中，有91％的人在研究中保持活跃，在学术界仍有76％的人继续进行，而18％的人来自低估 代表组。研究培训执行委员会（RTEC），完成计划董事 目前的四位导师将监督培训，职业发展和指导的进步， 批准新导师，并确保现有导师符合培训计划的指标。我们是 要求8个学员职位，平均支撑4个MD或MD-PHD学位的4个培训，4 每年博士学位。进入T32培训计划具有很高的竞争力 - 来自我们的才华横溢 候选池，选择约7％用于T32支持。我们将使学员接触临床，翻译或基本 代表当前艺术状态的研究技术。核心课程将包括培训 生物统计学，进行工作的会议，心血管精确系列，动手教学系列 心脏解剖结构和职业发展中心。学员还将参加年度务虚会 T32学员和导师的定期会议。通过这些互换，以临床为导向 学员将了解基本心血管生物学，基础科学学员将获得 了解重要的临床问题。该计划允许学员进一步量身定制培训 通过利用正式课程的出色机会和 BCH，HMS，Harvard公共卫生学院和麻省理工学院的无数科学半手和讲座。我们 还教学员团队合作的重要性，研究结果的清晰沟通，负责任 进行人类和实验室研究以及心理技能。学员进步的里程碑和指标 培训计划本身概述了，RTEC将在海外。相当大的机构 支持包括补充受训者的压力和旅行资金，以及对EAC和计划的支持 活动。在严格的实验台研究以及转化和临床方面的出色培训 互动和充满活力的计划中的调查将使毕业生成为小儿领导者 心脏病学和心血管研究。