Human Health Exposure Analysis Resource (HHEAR): Coordinating Center

人类健康暴露分析资源 (HHEAR)：协调中心

• 批准号: 10413850
• 负责人: BARBARA O'BRIEN
• 金额: $ 98.9万
• 依托单位: WESTAT, INC.
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-09-30 至 2024-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10413850
• 关键词: Access to Information; Address; Adherence; Adult; Biological; Books; Chemicals; Child; Child Health; Collaborations; Communication; Communities; Complex; Consult; Data; Data Analyses; Development; Electronic Mail; Ensure; Environmental Exposure; Epidemiologist; Evaluation; Exposure to; Extramural Activities; Genetic Predisposition to Disease; Goals; Health; Human; Infrastructure; Institution; Laboratories; Leadership; Life Cycle Stages; Link; Literature; Logistics; Longevity; Measures; Medical Research; Methodology; Methods; Monitor; National Institute of Environmental Health Sciences; Outcome; Performance; Positioning Attribute; Predisposition; Procedures; Process; Quality Control; Reporting; Research; Research Personnel; Research Priority; Resources; Risk Assessment; Sampling; Science; Services; Specimen; Standardization; Statistical Data Interpretation; Statistical Methods; System; Time; Toxicology; Training Activity; Update; Vision; Work; data repository; data resource; experience; indexing; insight; interest; method development; operation; prevent; programs; psychologic; quality assurance; social; social media; web portal; web site; working group

PROJECT SUMMARY/ABSTRACT The National Institute of Environmental Health Sciences (NIEHS) is establishing an infrastructure, the Human Health Exposure Analysis Resource (HHEAR), to provide the extramural research community access to laboratory and statistical analyses to add or expand the inclusion of environmental exposures in their research. HHEAR will be composed of three components: a Coordinating Center (CC), a National Exposure Assessment Laboratory Network, and an Exposure Data Repository and Resource for Statistical Analysis and Methods Development. This project will implement the CC for HHEAR. HHEAR will provide a range of sophisticated laboratory analyses and data services to the exposure science and health research community. The main goal of the CC is to provide researchers with a convenient and unified interface to access the available services of this complex network. The CC will (1) create and maintain a comprehensive index of HHEAR laboratory and data services, methodologies, and expertise available to researchers; (2) provide a public website as the primary means for researchers to access information about HHEAR’s capabilities and initiate proposals to use HHEAR’s resources; (3) establish and manage processes for proposal submission and evaluation; (4) monitor the progress of approved proposals and track services workflow; (5) define the quality standards by which the performance of HHEAR will be measured; (6) support the standardization of laboratory analyses and processes; (7) organize and support HHEAR oversight committees; (8) manage a Pilot and Feasibility Program; (9) develop and implement a strategic communication plan for HHEAR; (10) identify external resources of interest to exposure science and health research; and (11) leverage the HHEAR public website and social media to promote HHEAR’s available resources and accomplishments to the broader scientific community.

项目摘要/摘要 美国国家环境卫生科学研究所（NIEHS）正在建立基础设施，人类 健康暴露分析资源（HHEAR），以提供壁外研究社区的访问权限 实验室和统计分析以增加或扩展其研究中的环境暴露。 HHEAR将由三个组成部分组成：协调中心（CC），国家暴露评估 实验室网络，以及用于统计分析和方法的曝光数据存储库和资源 发展。该项目将实施HHEAR的CC。 HHEAR将提供一系列精致的 实验室分析和数据服务为曝光科学与健康研究社区。主要目标 CC的措施是为研究人员提供方便而统一的界面，以访问 这个复杂的网络。 CC将（1）创建和维护HHEAR实验室的全面指数和 研究人员可获得的数据服务，方法和专业知识； （2）提供一个公共网站作为 研究人员访问有关HHEAR功能的信息的主要手段，并启动建议使用 HHEAR的资源； （3）建立和管理提案提交和评估的流程； （4）监视器 批准的提案和跟踪服务工作流的进度； （5）定义质量标准 将测量HHEAR的性能； （6）支持实验室分析的标准化和 过程； （7）组织和支持HHEAR监督委员会； （8）管理飞行员和可行性 程序; （9）制定和实施HHEAR的战略沟通计划； （10）识别外部 曝光科学和健康研究的利益资源； （11）利用Hear公共网站 和社交媒体，以促进HHEAR的可用资源和成就，为更广泛的科学发展 社区。