ENDS use trajectories from adolescence through young adulthood: A longitudinal study of risk factors and profiles

ENDS 从青春期到成年早期的使用轨迹：风险因素和概况的纵向研究

基本信息

批准号：
10348132
负责人：
Melissa Blythe Harrell
金额：
$ 64.18万
依托单位：
UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON
依托单位国家：
美国
项目类别：
财政年份：
2019
资助国家：
美国
起止时间：
2019-02-15 至 2024-01-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10348132
关键词：
15 year old 17 year old Acceleration Adolescence Adolescent Adolescent and Young Adult Age Age-Years Area Behavior Behavioral Cigarette Cohort Studies Data Data Collection Demographic Factors Development Electronic Nicotine Delivery Systems Environmental Risk Factor Escalator Esthesia Ethnic Origin Exhibits Female Friends Growth Health Heterogeneity High Prevalence High School Student Hispanic Populations Life Life Cycle Stages Link Longitudinal Studies Marketing Measures Methodology Methods Modeling Natural History Nicotine Dependence Not Hispanic or Latino Online Systems Outcome Pattern Perception Persons Play Post Graduate Year Race Reporting Research Risk Risk Factors Role Sales Sampling Students Subgroup Surveys Testing Texas Time Tobacco Tobacco use age group austin behavioral health cigarette smoking cohort combustible tobacco design early adolescence effective intervention eighth grade follow-up high risk high school implementation intervention innovation junior high school male marijuana use metropolitan peer population based preventive intervention sex sixth grade tenth grade tobacco products underage drinking uptake young adult

项目摘要

ABSTRACT The primary objective of this study is to identify, describe, and differentiate stable and persistent patterns in trajectories of ENDS use, from 11 to 22 years of age. Seventy percent of adolescent never users will be susceptible to ENDS and other tobacco use by the age of 17 – and, by age 22, in young adulthood, the same proportion will have ever used ENDS or tobacco. Understanding what accelerates this rapid progression in tobacco use behaviors and related outcomes from them (e.g., nicotine dependence) will help inform the development of effective interventions. Considerable controversy exists regarding the role that electronic nicotine delivery systems (ENDS) play in the uptake, progression, and/or cessation of combustible tobacco product use, and appropriate ways to measure and model this. To date, almost all studies of ENDS use behaviors are either cross-sectional or limited to short-term (e.g., 1 year) follow-up, which is inadequate for identifying sustained patterns in ENDS use trajectories across the life course, given that transitions in tobacco use behaviors (i.e., initiation to sustained use or quitting) and between tobacco products (e.g., ENDS and cigarettes) are frequent and erratic. Longer-term studies of patterns in ENDS use trajectories are critical, but they will require additional data collection efforts; especially, regionally. Using a cohort-sequential design, we propose to follow and connect 3 existing, population-based cohorts of adolescents (11-15 years old at Wave 1, 2014-15) through young adulthood (18-22 years old at Wave 14, 2021), to represent developmental changes in ENDS use behaviors across these critical stages in the life course. At Wave 1, during the 2014-15 academic year, the sample included 3,907 (N=461,069) students in the 6th, 8th, and 10th grades in 79 middle schools and high schools (N=1969) in the 4 largest metropolitan areas of Texas: Houston, Dallas/Ft. Worth, San Antonio, and Austin. At Wave 8 (June, 2018), retention remained high, at 85%; the oldest cohort is now 1 year post high school. We propose to follow these cohorts for an additional 6 waves of data collection, every 6 months, to track them all through high school (1, 3, and 5 years post-graduation), into young adulthood. Our web-based surveys include robust measures of ENDS use and other tobacco use behaviors; nicotine dependence; and a broad spectrum of potential risk factors, including intrapersonal, interpersonal, and environmental influences. Growth mixture models shall be applied to these data to empirically identify stable developmental patterns in ENDS use behaviors, from 11 to 22 years of age; we anticipate there will be substantial heterogeneity in them. We will be able to identify young adult outcomes of persistent patterns in ENDS use that begin in adolescence; and risk factors in adolescence that predict ENDS use trajectories that persist into young adulthood. The use of combustible tobacco products in adolescence and young adulthood will be considered, accordingly. Almost all (>95% of) existing cohorts and studies of ENDS use focus on either adolescents or young adults. Very few, like ours, are able to track adolescents into young adulthood to investigate developmental trajectories of risk.

抽象的本研究的主要目的是识别、描述和区分稳定和持久的模式 11 至 22 岁的 ENDS 使用轨迹 70% 的青少年从未使用过。 17 岁时容易受到 ENDS 和其他烟草使用的影响，而到 22 岁时，在成年初期，同样容易受到 ENDS 和其他烟草使用的影响的比例曾经使用过电子尼古丁传送系统或烟草。了解是什么加速了这种快速发展。烟草使用行为及其相关结果（例如尼古丁依赖）将有助于告知关于电子技术的作用存在相当大的争议。尼古丁输送系统 (ENDS) 在可燃烟草的吸收、进展和/或停止中发挥作用产品的使用，以及测量和建模的适当方法迄今为止，几乎所有有关 ENDS 使用的研究都已完成。行为要么是跨部门的，要么仅限于短期（例如 1 年）的随访，这不足以考虑到烟草的转变，识别电子尼古丁传送系统在整个生命过程中的使用轨迹的持续模式使用行为（即开始持续使用或戒烟）以及烟草制品之间（例如电子烟和电子烟）对 ENDS 使用轨迹模式的长期研究至关重要，但是。他们将需要额外的数据收集工作；特别是，我们使用队列序列设计。建议追踪并联系 3 个现有的、基于人口的青少年群体（第一波为 11-15 岁， 2014-15）到青年期（2021 年第 14 波中的 18-22 岁），以代表 ENDS 在生命历程的这些关键阶段使用行为，即 2014-15 学年期间的第一波。去年，样本包括 79 所中学的 6、8 和 10 年级的 3,907 名学生（N=461,069）德克萨斯州 4 个最大都市区的高中 (N=1969)：休斯顿、达拉斯/沃斯堡、圣安东尼奥、和奥斯汀，在第 8 波（2018 年 6 月）中，保留率仍然很高，为 85%；现在是最高值一年后的一年；我们建议每 6 个月跟踪这些队列一次额外的 6 波数据收集，以跟踪他们从高中（毕业后 1 年、3 年和 5 年）一直到我们基于网络的成年期。调查包括对电子尼古丁传送系统使用和其他烟草使用行为的强有力衡量；以及广泛的潜在风险因素，包括个人内部、人际和环境影响。生长混合模型应应用于这些数据，以凭经验确定稳定的发育模式 11 岁至 22 岁的电子烟使用行为我们预计会有很大的异质性。我们将能够确定从青春期开始持续使用电子尼古丁传送系统的年轻人的结果；预测 ENDS 的青春期风险因素使用的轨迹一直持续到成年早期。因此，几乎所有青春期和青年期的可燃烟草制品都会被考虑。 (>95%) 现有的 ENDS 使用队列和研究集中于青少年或年轻人。像我们一样，能够追踪青少年到成年早期，以调查风险的发展轨迹。