Recovering Individual Memory Problems Histories from Own and Proxy Retrospective Reports: A Feasibility Study
从自己和代理人的回顾报告中恢复个人记忆问题的历史:可行性研究
基本信息
- 批准号:10288967
- 负责人:
- 金额:$ 25.09万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2020
- 资助国家:美国
- 起止时间:2020-09-11 至 2024-05-31
- 项目状态:已结题
- 来源:
- 关键词:AddressAgingAlgorithmsAlzheimer&aposs disease diagnosisAlzheimer&aposs disease related dementiaBiological MarkersBrainCalendarCellsCharacteristicsChinaCommunitiesComplementCountryCross-Sectional StudiesDataData ReportingDementiaDiabetes MellitusDiagnosisDisadvantagedDiseaseEducationElderlyEuropeEventEvolutionExerciseFeasibility StudiesFundingGoalsGoldGovernmentHealthHealth SurveysHealth and Retirement StudyHouseholdImpaired cognitionIncidenceIndividualInternationalInvestmentsLifeLife Cycle StagesLiteratureLongitudinal StudiesLongitudinal SurveysMeasurementMeasuresMemoryMemory LossMethodsModelingNational Health Interview SurveyObesityPathologicPatient Self-ReportPatientsPersonsPopulationPrevalenceProxyRecording of previous eventsReportingResearch PersonnelRespondentRetirementSamplingSourceStrokeStructureSurveysSymptomsVisiting NurseWorkaging demographicaging populationbasedesignhealth datainsightinterestlife historynutritionpanel study of income dynamicsparent projectpredictive testsuccess
项目摘要
Project Summary
In the project, "Recovering Individual Memory Problems Histories from Own and Proxy
Retrospective Reports: A Feasibility Study," we will adapt and extend the well-known Langa-
Weir method to estimate the prevalence of Alzheimer’s Disease and Related Dementias
(ADRD) over the life-course of individuals. Our aims are explore whether and under what
conditions one can use that method to identify incipient ADRD in earlier life stages and how well
the method works. We focus specifically on ADRD not only because it is a critical issue faced by
most of the world’s populations but also because it is part of a class of diseases that share two
important features. First, in early stages of ADRD, patients present symptoms that are difficult to
interpret and that might be caused by multiple and very different diseases. Second, after a
person clearly has ADRD, that person increasingly finds it more and more difficult to remember
and report whether and when their symptoms began. The first characteristic implies that,
compared to contemporaneously collected data, retrospectively reported data might better
measure prevalence in populations at the early stages of ADRD. The second characteristic
implies that self-reported retrospective data will likely be less accurate than retrospective reports
of proxy respondents (who know the respondent’s history). Our project leverages, complements,
and benefits from the approach, data, and structure in our recently funded R21 project titled,
“Constructing, Validating, and Testing the Predictive Power of Life-Course Health Histories.” In
particular we will use the life course histories of other diseases as covariates in our model to
predict incipient ADRD. This supplemental project will dive more deeply into the specific issues
associated with ADRD. As in the parent project, our overall aims are to conduct a “proof-of-
concept” exercise to explore whether and for what conditions one can use retrospective
questions to generate life health histories and to provide a guide for researchers to use. Our
work products will expand the set of questions researchers can address with retrospective
health data already collected on existing surveys. The supplemental project will yield insights on
the specific issues associated with ADRD.
项目摘要
在项目中,“从自己和代理中恢复单个内存问题历史
回顾性报告:一项可行性研究:“我们将适应并扩展众所周知的兰加 -
堰方法估计阿尔茨海默氏病和相关痴呆症的患病率
(ADRD)关于个人的生命课程。我们的目标是探索是否以及
条件可以使用该方法在早期的生活阶段识别初期ADRD,以及
该方法有效。我们专门关注ADRD,不仅是因为这是面临的关键问题
世界上大多数人口中的大多数人,也是因为它是一类疾病的一部分
重要功能。首先,在ADRD的早期,患者表现出难以
解释,这可能是由多种和非常不同的疾病引起的。第二,之后
人显然有adrd,那个人越来越难以记住
并报告是否以及何时开始症状。第一个特征意味着,
与当代收集的数据相比,回顾性报告的数据可能更好
测量ADRD早期阶段人口的患病率。第二个特征
意味着自我报告的回顾性数据可能不如回顾性报告准确
代理受访者(知道受访者的历史)。我们的项目利用,完成,
并从我们最近资助的R21项目中的方法,数据和结构中受益。
“构建,验证和测试生命课健康历史的预测能力。”在
特别是我们将使用其他疾病的生活历史作为模型中的协变量
预测初期ADRD。这个补充项目将更深入地研究特定问题
与Adrd相关。与母公司项目一样,我们的总体目标是进行“证明
概念”练习,以探索是否以及在什么条件下可以使用回顾性
产生生命健康历史的问题,并为研究人员提供指南。我们的
工作产品将扩大研究人员可以回顾性解决的问题集
现有调查已经收集了健康数据。补充项目将产生有关的见解
与ADRD相关的具体问题。
项目成果
期刊论文数量(0)
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Dean R Lillard其他文献
Dean R Lillard的其他文献
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{{ truncateString('Dean R Lillard', 18)}}的其他基金
Vaccine Hesitancy: Exploring the Role of Temporal and Cross-country Variation in COVID Rules, Vaccine Media Coverage, and Public Health Policy Consistency
疫苗犹豫:探索时间和跨国差异在新冠肺炎规则、疫苗媒体报道和公共卫生政策一致性中的作用
- 批准号:
10792031 - 财政年份:2023
- 资助金额:
$ 25.09万 - 项目类别:
The economic and social impact of COVID-19 mitigation policies: A cross-country analysis of macro events
COVID-19 缓解政策的经济和社会影响:宏观事件的跨国分析
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10577790 - 财政年份:2021
- 资助金额:
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The economic and social impact of COVID-19 mitigation policies: A cross-country analysis of macro events
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10386913 - 财政年份:2021
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$ 25.09万 - 项目类别:
The economic and social impact of COVID-19 mitigation and vaccination policies: Supplement for special issues & associated conferences
COVID-19 缓解和疫苗接种政策的经济和社会影响:特殊问题的补充
- 批准号:
10845793 - 财政年份:2021
- 资助金额:
$ 25.09万 - 项目类别:
The economic and social impact of COVID-19 mitigation policies: A cross-country analysis of macro events
COVID-19 缓解政策的经济和社会影响:宏观事件的跨国分析
- 批准号:
10185767 - 财政年份:2021
- 资助金额:
$ 25.09万 - 项目类别:
Constructing, Validating, and Testing the Predictive Power of Life-Course Health Histories
构建、验证和测试生命历程健康史的预测能力
- 批准号:
10064355 - 财政年份:2020
- 资助金额:
$ 25.09万 - 项目类别:
Constructing, Validating, and Testing the Predictive Power of Life-Course Health Histories
构建、验证和测试生命历程健康史的预测能力
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10260541 - 财政年份:2020
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$ 25.09万 - 项目类别:
Archiving, Enhancing, and Expanding the Cross-National Equivalent File
归档、增强和扩展跨国等效文件
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酒精广告、酒后驾驶:针对未成年人和成人的研究
- 批准号:
8473140 - 财政年份:2012
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Alcohol Advertising, Drinking and Driving: A Study of Underage Youth and Adults
酒精广告、酒后驾驶:针对未成年人和成人的研究
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