Zeiss Lightsheet 7 microscope

蔡司 Lightsheet 7 显微镜

• 批准号: 10176906
• 负责人: Exing Wang
• 金额: $ 55.93万
• 依托单位: UNIVERSITY OF TEXAS HLTH SCIENCE CENTER
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-06-15 至 2022-06-14
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10176906
• 关键词: Area; Award; Biomedical Research; Brain Injuries; Cancer Center; Cancer Grant Supplements (P30); Cities; Communities; Core Facility; Digestive System Disorders; Discipline; Disease; Funding; Health; Institution; Investigation; Laboratories; Lead; Light; Malignant Neoplasms; Microscope; NCI-Designated Cancer Center; Neurodegenerative Disorders; Osteoporosis; Research; Research Personnel; Research Project Grants; Resolution; Services; Site Visit; Specimen; Three-Dimensional Imaging; Toothache; Toxic effect; Uncertainty; United States National Institutes of Health; Vision; biological systems; bone loss; imaging modality; innovation; instrument; novel therapeutic intervention; optical imaging

Project Summary This request is for funds to purchase a Zeiss Light Sheet 7 microscope. This instrument will be housed, managed, and maintained by the Optical Imaging Core Facility (OIF) at UT Health San Antonio (UT Health SA), which is jointly managed by UT Health SA and the Mays Cancer Center. The OIF supports 70 NIH-funded laboratories. Last year alone, the OIF supported 92 externally funded research projects with a total award amount of more than $55 million. As a component of Mays Cancer Center, an NCI designated cancer center, the OIF received an “Outstanding” rating during the recent on site visit for the NIH/NCI P30 grant renewal. The type of instrument requested is currently unavailable at UT Health SA and at any other institutions in the city of San Antonio. The acquisition of this new imaging modality is considered essential in order for the OIF to continue providing the needed services to our research community, in particular, for achieving rapid, low toxicity, high-resolution, three-dimensional imaging of a broad range of specimens for a large number of NIH-funded research projects. The new instrument is particularly critical to the major users listed in the proposal, whose highly competitive and innovative research is dependent on the availability of this instrument. Investigators, including both well-established and new, from diverse research areas, will greatly benefit. The new instrument can truly lead to a better understanding basic biological systems and to develop novel therapeutic strategies in treating many diseases states, including cancer, brain injury, degenerative neurological disease, dental pain, vision disease, osteoporosis and bone loss, and digestive disease. The availability of this new instrument will also stimulate other investigators at UT Health SA and nearby institutions to move their research into exciting and highly competitive new directions. Overall, this acquisition will without a doubt, significantly impact a large number of NIH-funded investigations covering an expansive array of disciplines in biomedical research.

项目摘要 此请求是要购买Zeiss Light Sheet 7显微镜的资金。这个乐器将是 由UT Health SAN的光学成像核心设施（OIF）安装，管理和维护 由UT Health SA和Mays Cancer共同管理的Antonio（UT Health SA） 中心。 OIF支持70个NIH资助的实验室。仅去年，OIF就支持92 奖励总额超过5500万美元的外部资助的研究项目。作为 NCI指定癌症中心Mays Cancer Center的组成部分，OIF接受了 在最近的NIH/NCI P30授予申请的现场访问中，“出色”的评级。类型 目前，UT Health SA和任何其他机构目前都无法获得所请求的工具 圣安东尼奥市。获取这种新成像方式被认为是必不可少的 命令OIF继续向我们的研究社区提供所需的服务， 特别是为了实现快速，低毒性，高分辨率，三维成像 大量NIH资助的研究项目的标本范围。新乐器是 对于该提案中列出的主要用户尤其重要，该提案竞争激烈， 创新的研究取决于该工具的可用性。调查人员，包括 来自潜水员研究领域的建立良好的和新的都将大大受益。新的 仪器可以真正导致更好地理解基本的生物系统并开发 治疗许多疾病状态的新型治疗策略，包括癌症，脑损伤， 退化性神经疾病，牙齿疼痛，视力疾病，骨质疏松和骨质流失，以及 消化疾病。该新工具的可用性还将刺激其他调查人员 UT Health SA和附近的机构，将他们的研究转变为令人兴奋且竞争激动人心的 新方向。总体而言，这次收购将毫无疑问会大大影响大量 NIH资助的研究涵盖了生物医学研究中的额外学科。