Admin Core

管理核心

基本信息

批准号：
10159903
负责人：
CHARLOTTE Ann GAYDOS
金额：
$ 34.65万
依托单位：
JOHNS HOPKINS UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2007
资助国家：
美国
起止时间：
2007-09-30 至 2023-05-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10159903
关键词：
Address Biological Assay Biomedical Engineering Clinical Collaborations Communication Communities Complex Conflict (Psychology)Consensus Databases Development Diagnostic Discipline Engineering Ensure Epidemic Evaluation Fostering Funding Goals HIV Human Resources Individual Industry Institutes Lead Leadership Maintenance National Institute of Biomedical Imaging and Bioengineering Nature Performance Point of Care Technology Procedures Progress Reports Publications Research Research Personnel Resources Role Science Scientist Services Sexual Health Sexually Transmitted Diseases Structure System Technology Testing Training United States National Institutes of Health Update Validation Work clinical translation commercialization design health inequalities improved innovation low and middle-income countries meetings member multidisciplinary outreach point of care point of care testing prototype support network website development

项目摘要

Project Summary Administrative Core The Administrative Core, through the development and implementation of strategic integrated management systems, will work to support the Center of Excellence for the Development and Testing of Point-of-Care Tests (POCT) for Sexually Transmitted Diseases (STDs). We will lead, support, and assist our Cores to integrate and build multidisciplinary partnerships; to ensure outreach and communications to guarantee the inclusion of diverse expertise investigators, industry scientists, and engineers; to evaluate performance and guide performance improvement; and to cultivate service excellence in order to reach our Center's overall goals and specific aims, as well as the goals of the POC Technologies Research Network. The goals of our Administrative Core include addressing the epidemics of STDs/HIV in the U.S. and in low and middle income countries by development and better use of Point-of-Care (POC) tests, to address health inequity and improve sexual health. 1. We will support the Center of Excellence and all the individual Cores by assisting them for the development and verification of POC technologies via collaborative efforts that merge scientific and technological capabilities with clinical need and training of developers, as well as end users of POCT. 2. We will support the Cores as they use clinical drivers of technology progression for developing new and expanding existing POC Tests, by providing assistance insure that milestones for each project are met. 3. We will help to implement functioning core components that work smoothly together in a collaborative fashion and with other members of the Point-of-Care Technologies Research Network (POCTRN). 4. Our Administrative Core will implement a smooth transition along a pipeline from developmental of prototype assays through early in-house, clinical translation and validation testing. 5. Our operational administration will assist Cores to ascertain needs of end users of POC, train scientists, fund scientists and biomedical engineers for development of prototype and mature POC technologies, as well as pilot test and validate POC tests in diverse clinical settings. In this coordinated manner, we can assist with the logical development of POC assays, which will have sufficient scientific merit to progress to FDA submission and ultimate commercialization.

项目概要行政核心行政核心，通过制定和实施战略综合管理系统，将致力于支持卓越中心性传播即时检测 (POCT) 的开发和测试疾病（STD）。我们将领导、支持和协助我们的核心整合和建设多学科伙伴关系；确保外展和沟通，以保证吸收不同专业知识的调查人员、行业科学家和工程师；评估绩效并指导绩效改进；并培养卓越的服务，以便实现我们中心的总体目标和具体目标，以及 POC 的目标技术研究网络。我们行政核心的目标包括解决性传播疾病/艾滋病毒在美国和低收入和中等收入国家的流行情况更好地利用即时护理 (POC) 测试，解决健康不平等问题并改善性健康。 1. 我们将通过协助卓越中心和所有单独的核心来支持他们通过融合科学的协作努力来开发和验证 POC 技术和技术能力与临床需求和开发人员培训以及最终 POCT的用户。 2. 我们将支持核心使用技术的临床驱动力通过提供帮助来开发新的和扩展现有的 POC 测试确保达到每个项目的里程碑。 3.我们将帮助实施核心功能以协作方式并与其他成员顺利协作的组件即时护理技术研究网络 (POCTRN)。 4. 我们的行政核心将实现原型检测开发过程中的平稳过渡通过早期的内部临床转化和验证测试。 5. 我们的运营管理部门将协助 Cores 确定 POC 最终用户的需求、培训科学家、提供资金科学家和生物医学工程师开发原型和成熟的 POC 技术，以及在不同临床环境中进行试点测试和验证 POC 测试。在这个以协调的方式，我们可以协助 POC 检测的逻辑开发，这将有有足够的科学价值来向 FDA 提交申请并最终商业化。