Preventing Opioid Overdose Mortality in the United States

预防美国阿片类药物过量死亡

基本信息

批准号：
10164091
负责人：
Barrot Hopkins Lambdin
金额：
$ 16.44万
依托单位：
RESEARCH TRIANGLE INSTITUTE
依托单位国家：
美国
项目类别：
财政年份：
2018
资助国家：
美国
起止时间：
2018-07-15 至 2022-05-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10164091
关键词：
2019-nCoV Adopted Affect Alcohol or Other Drugs use Buprenorphine COVID-19 COVID-19 pandemic Cessation of life Cities Communicable Diseases Communities Community based prevention County Cross-Sectional Studies Drug user Education Enrollment Future Geography Goals Grant Health Services Home environment Hour Human Resources Individual Injecting drug user Interview Knowledge Link Location Measures Methadone Modeling Naloxone Needle-Exchange Programs Opioid Overdose Participant Patients Persons Preparation Preventive Intervention Process Proliferating Public Health Reporting Rural Service delivery model Services Shelter facility Social Distance Surveys Syringes United States Virus base experience falls implementation science improved interest member mortality novel coronavirus operation opioid epidemic opioid overdose opioid use disorder overdose prevention pandemic disease prescription opioid prevent programs response screening service programs suburb transmission process

项目摘要

We are proposing an urgent competitive revision for our current grant (R01DA04686702) to study the impact of the novel coronavirus (COVID-19) pandemic on syringe service programs (SSPs) throughout the United States (US). The COVID-19 pandemic has rapidly proliferated and caused unprecedented disruption to health and health services in the US and has the potential to reverse recent reductions in the nation's opioid overdose mortality rate. As cities, counties, and states tried to stunt the transmission and impact of COVID- 19, they began rolling out various social distancing orders (e.g., Shelter-in-Place). A consequence of these public health mandates and the need to protect people from COVID-19 has been disruptions in services for people who inject drugs (PWID). Particularly in the context of the opioid epidemic, understanding how the COVID-19 pandemic has affected services for people who use drugs is critical to know how to respond within the current pandemic and to be better prepared for future public health crises. SSPs have been the mainstay for community-based prevention efforts for PWID and have pioneered efforts for implementing overdose education and naloxone distribution (OEND) and improving enrollment into medications for opioid use disorder (MOUD) programs. SSPs are considered an “essential service” and have not been mandated to suspend services during Shelter-in-Place orders. As part of our nationwide study of SSPs, our study team has documented that SSPs are facing unprecedented challenges and adapting implementations, as necessary. Leveraging our ongoing study, we propose to build a comprehensive understanding of adaptations made in response to COVID-19. Using the exploration, preparation, implementation, and sustainment (EPIS) framework, we propose to systematically assess the impacts of the COVID-19 pandemic on SSP services in the US. Our proposed aims are as follows: Aim 1: To characterize the response to COVID-19 regarding the delivery of syringe services, overdose education and naloxone distribution, and medications for opioid use disorder among SSPs; Aim 2: To describe barriers and facilitators among SSPs regarding implementation of syringe services, overdose education and naloxone distribution, and medications for opioid use disorder during the COVID-19 pandemic. To achieve these aims, we will conduct a cross-sectional study with all SSPs (N = 407) in the US in late summer/fall 2020. In addition, we will conduct in-depth interviews with 36 SSPs from geographically diverse urban, suburban, and rural locations where we observe varying levels of implementation experiences—de-implementation of services, adapted implementations, and implementation as usual—during the COVID-19 pandemic. Understanding how the COVID-19 pandemic has impacted services for PWID is critical for improving our response within the current pandemic and being better prepared for future pandemics.

我们正在为目前的赠款（R01DA04686702）进行紧急竞争修订，以研究影响整个联合的新颖的冠状病毒（Covid-19）大流行（SSPS）国家（美国）。 19009年大流行迅速增殖，并造成了前所未有的破坏美国的健康和卫生服务，有可能扭转该国阿片类药物的最新减少过量死亡率。作为城市，县和各州试图阻止Covid-的传播和影响 19，他们开始推出各种社会距离的命令（例如，现场庇护所）。这些结果公共卫生规定和保护人们免受19009的需求，这是对服务的中断注射毒品的人（PWID）。特别是在阿片类药物流行的背景下，了解 Covid-19-大流行对使用毒品的人们的服务对知道如何做出反应至关重要在当前的大流行中，为未来的公共卫生危机做好了准备。 SSP是基于社区的PWID预防努力的支柱，并为实施而开创了努力过量的教育和纳洛酮分布（OEND）并改善了Ooid药物的入学率使用障碍（MOUD）程序。 SSP被认为是“基本服务”，尚未被要求在现场订单期间暂停服务。作为我们全国范围内SSP研究的一部分，我们的学习团队已经记录说，SSP面临着前所未有的挑战和适应实施，必要的。利用我们正在进行的研究，我们建议对对COVID-19进行的适应。使用探索，准备，实施和维持（EPIS）框架，我们建议系统地评估Covid-19的大流行的影响在美国的SSP服务上。我们提出的目标如下：目标1：表征对 COVID-19关于提供注射器服务，过量教育和纳洛酮分布以及 SSP中的烯烃使用障碍药物；目标2：描述SSP中的障碍和促进者关于实施注射器服务，过量教育和纳洛酮分布以及在Covid-19大流行期间，用于生蛋白使用障碍的药物。为了实现这些目标，我们将进行 2020年夏末/秋季，美国所有SSP（n = 407）的横断面研究。此外，我们将对来自地理上的城市，郊区和粗糙地点的36个SSP进行深入的访谈在观察到不同级别的实施经验的地方 - 服务的实施，适应实施和像往常一样的实施 - 在Covid-19-19的大流行中。了解如何 COVID-19大流行对PWID的影响对于改善当前的反应至关重要大流行，为将来的大流行做好准备。

项目成果

期刊论文数量（8）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

How do contextual factors influence naloxone distribution from syringe service programs in the USA: a cross-sectional study.

DOI：
10.1186/s12954-023-00755-4
发表时间：
2023-02-28
期刊：
HARM REDUCTION JOURNAL
影响因子：
4.4
作者：
Lambdin, Barrot H.;Wenger, Lynn;Bluthenthal, Ricky;Bartholomew, Tyler S.;Tookes, Hansel E.;LaKosky, Paul;O'Neill, Savannah;Kral, Alex H.
通讯作者：
Kral, Alex H.

Availability of telehealth-based services at syringe services programs under the COVID-19 Public Health Emergency.

DOI：
10.1186/s12954-023-00861-3
发表时间：
2023-09-02
期刊：
HARM REDUCTION JOURNAL
影响因子：
4.4
作者：
Bartholomew, Tyler S.;Tookes, Hansel E.;Chueng, Teresa A.;Bluthenthal, Ricky N.;Wenger, Lynn D.;Kral, Alex H.;Lambdin, Barrot H.
通讯作者：
Lambdin, Barrot H.

Best practices for community-based overdose education and naloxone distribution programs: results from using the Delphi approach.

DOI：
10.1186/s12954-022-00639-z
发表时间：
2022-05-28
期刊：
HARM REDUCTION JOURNAL
影响因子：
4.4
作者：
Wenger, Lynn D.;Doe-Simkins, Maya;Wheeler, Eliza;Ongais, Lee;Morris, Terry;Bluthenthal, Ricky N.;Kral, Alex H.;Lambdin, Barrot H.
通讯作者：
Lambdin, Barrot H.

Ingenuity and resiliency of syringe service programs on the front lines of the opioid overdose and COVID-19 crises.