Joint Study on the Development of Novel Joint Prostheses

新型关节假体开发联合研究

基本信息

批准号：
10044165
负责人：
MURAKAMI Teruo
金额：
$ 2.5万
依托单位：
KYUSHU UNIVERSITY
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (B).
财政年份：
1998
资助国家：
日本
起止时间：
1998 至 1999
项目状态：
已结题

项目摘要

The object of this research is to conduct the joint research between Kyushu University, The University of Leeds and University of Bradford to elucidate the lubrication and wear mechanism in artificial joints and develop novel joint prostheses. Members of this joint research visited Japan or United Kingdom for mutual discussion. Furthermore, during their visiting the presentations of papers on this research project were carried out at the international conferences, I.e., at the Third World Congress of Biomechanics, 25th Leeds-Lyon Symposium on Tribology, 1st Asia Int. Conf. on Tribology, Asiatrib'98, 26th Leeds-Lyon Symposium on Tribology and 12th International Symposium on Ceramics in Medicine. At the International Symposium on Lubrication Mechanism in Natural and Artificial Joints, which was organized by Prof. Murakami and Prof. Fisher at the 25th Meeting of Japanese Society of Clinical Biomechanics and Related Research, Dr. Jin and Dr. Sawae presented their papers as symposists.In th … More is joint study, the following results were shown. The fundamental mechanism in adaptive multimode lubrication in natural synovial joints was discussed by focusing the lubricating ability of cartilage surface layer. The geometric feature of knee joint was indicated by 3D Computer Graphics technique. On the lubrication mechanism in artificial joints, the fluid film formation, friction or wear in knee prosthesis models with compliant artificial cartilage such as polyurethane, silicone rubber, polyvinylalcohol (PVA) hydrogel and semi-interpenetrating polymer network (SIPN) hydrogel were evaluated by simulator or sliding tests. Atomic Force Microscopy (AFM) observation was effective in evaluation of changes in surface layer of natural articulator cartilage and artificial cartilage. The superiority in fluid film formation during walking for transverse elliptical conjunction to longitudinal one with the same contact area in knee prostheses was shown in numerical analysis. The friction and wear in existing artificial joints composed of metal or ceramics and ultra-high molecular weight polyethylene (UHMWPE), ceramics-on-ceramics, metal-on-metal were evaluated by unidirectional and multidirectional sliding tests and simulators. The influence of multi-directional motion, constituents of lubricants, material properties and geometrical design with surface roughness on wear behavior were summarized. The properties of wear particles and their biological reaction were investigated. The friction control of elastomeric material by applied electric field and wear reduction of metal-on-metal pair by magnetic field were demonstrated. Less

九州大学的联合搜索对人工关节假体中的润滑和磨损机械性。 Int。临床生物力学和相关的研究，Jin Sawae博士作为介学家提出了论文。在以下结果中，通过集中了软骨表面层的润滑能力来讨论自适应多模润滑的基本机制。他在人造关节中的含液，流体膜，膝盖假体模型，例如多核，有机硅橡胶，聚乙烯基醇（PVA）水凝胶和半融合聚合物网络（SIPN）TS。在评估自然关节卡片软骨的表面层的变化中，在膝关节中，在膝盖中，横向椭圆形结合在纵向的纵向上。金属或陶瓷和分子T聚乙烯（UHMWPE），陶瓷在陶瓷上，金属在金属中通过单向和多边形滑动测试和模拟器进行多方向运动，粘液剂，材料，材料，材料，材料，材料，材料，材料，杂物性，材料，材料，材料，材料，材料，材料，材料，并评估金属。总结了磨损行为的粗糙度