Development and its Application of Functional Membranes by Molecular Imprint Technique via Phase Inversion Precipitation

反相沉淀分子印迹技术开发功能膜及其应用

• 批准号: 09650842
• 负责人: KOBAYASHI Takaomi
• 金额: $ 1.86万
• 依托单位: Nagaoka University of Technology
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 1997
• 资助国家: 日本
• 起止时间: 1997 至 1999
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-09650842/
• 关键词: Molecular imprinting; Functional Membranes; Separation Membranes; Recognition; Temlate; Polymer; Permeability; Membrane separation; 高分子膜; 鋳型分子; 分子刷り込み; カフェイン; 相分離法; ポリアクリロニトリル; ポリアミド; 刷り込み特性; テオフィリン

Phase inversion of polyacrylonitrile copolymers with carboxylic acid groups was applied to prepare molecular imprinting membranes of theophylline (THO). The copolymer cast solution of dimethylsulfoxide (DMSO) with the THO template was immersed in water and then the polymer including the template is coagulated in the nonsolvent. After removal of the template from the solidified copolymer membrane, high selectivity for THO molecule was recognized compared to Caffeine recognition by the THO imprinted-membranes. The molecular imprint process was affected by the template concentration in the DMSO cast solution, coagulation condition and carboxylic acid contents in the copolymer. The high binding selectivity of THO solute to the THO imprinted copolymer membrane arise from the formation of the imprinted sites, which consist of free OH group of carboxylic acid segments for hydrogen bonds with the solute

采用带有羧酸基团的聚丙烯腈共聚物的相转化法制备了茶碱（THO）分子印迹膜。将带有THO模板的二甲基亚砜(DMSO)的共聚物浇注溶液浸入水中，然后包含模板的聚合物在非溶剂中凝固。从固化的共聚物膜上去除模板后，与 THO 印迹膜对咖啡因的识别相比，对 THO 分子的选择性较高。分子印迹过程受到DMSO浇铸溶液中模板浓度、凝固条件和共聚物中羧酸含量的影响。 THO溶质与THO印迹共聚物膜的高结合选择性源于印迹位点的形成，该印迹位点由与溶质形成氢键的羧酸链段的游离OH基团组成

项目成果

T.Kobayashi,H.Y.Wang,T.Fukaya and N.Fujii,: "Recogition with Imprinted Polymers,ACS Symposium Series703,Washington,DC," Molecular Imprint Membranes Prepared by Phase Inversion of Polyacrylonitrile Copolymers With Carboxylic Acid Groups,13 (1998)

T.Kobayashi、H.Y.Wang、T.Fukaya 和 N.Fujii，“Recogition with Imprinted Polymers，ACS Symposium Series703，华盛顿特区”，通过带羧酸基团的聚丙烯腈共聚物相转化制备分子印迹膜，13 (1998)

T. Kobayashi, H. Y. Wang, T. Fukaya and N. Fujii: "Recognition with Imprinted Polymers, ACS Symposium Series 703, Washington DC"Molecular Imprint Membranes Prepared by Phase Inversion of Polyacrylonitrile Copolymers with Carboxylic Acid Groups. 13 (1998)

T. Kobayashi、H. Y. Wang、T. Fukaya 和 N. Fujii：“印迹聚合物识别，ACS 研讨会系列 703，华盛顿特区”通过带有羧酸基团的聚丙烯腈共聚物的相转化制备分子印迹膜。

T.Kobayashi, H.Y.Wang and N.Fujii: "ACS symposium series on Molecular and ionic recognition with imprinted polymers" America Chemical Society (in press), (1998)

T.Kobayashi、H.Y.Wang 和 N.Fujii：“ACS 研讨会系列关于分子和离子识别的印迹聚合物”美国化学会（正在出版），（1998 年）

Kobayashi et al.: "Porous Nylon-6 membranes with dithioamino groups for low pressure desalination"Journal of Applied Polymer Science. 75. 1546-1553 (2000)

Kobayashi 等人：“用于低压海水淡化的带有二硫氨基的多孔尼龙 6 膜”应用聚合物科学杂志。

Kobayashi et al: "Molecular imprint membranes polyacrylonitrile copolymers with different acrylic acid segments"Analytica Chimica Acta. 365. 81-88 (1999)

Kobayashi 等人：“具有不同丙烯酸片段的聚丙烯腈共聚物分子印迹膜”Analytica Chimica Acta。