Design and Function of Multi-antenna Molecule

多天线分子的设计与功能

基本信息

批准号：
09650937
负责人：
NAKATSUJI Yohji
金额：
$ 2.11万
依托单位：
Osaka University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
1997
资助国家：
日本
起止时间：
1997 至 1999
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-09650937/
关键词：
molecular recognition alkali metal cation alkaline earth metal cation fluorescence spectra complexation crown ether 合成イオノホア錯形成態錯形成能

项目摘要

In this study, we developed a variety of multi-antenna molecules which can discriminate the specified guest ion by using the plural electron-donating sidearms. The results are summarized as follows.1. A new series of C-pivot tripodal ligands containing a 2-methylglycerol unit were prepared and their complexation properties toward alkali metal cations were examined. This type of compounds showed a relatively higher complexing ability, which was reasonably explained by considering that it takes a three dimensional coordination towards the cations.2. New lipophilic double-armed crown ethers were designed and prepared for assessment of the ability of the crown ring to form a complex with alkali metal cations at an air-water interface. The p-A isotherm of the crown ethers changed with the addition of alkali metal salts, and such changes were speculated to be dependent on complexation ability at the interface.3. A new series of C-pivot lariat ethers having an oxyquinoline moiety as a part of … More the electron-donating sidearm were obtained from crown ether derivatives of low symmetry such as 3n-methylene- (3n+1) -crown-n (n=5,6,7) and their complexation properties toward alkali metal cations were evaluated. As a result, KィイD1+ィエD1 selectivity was attained by 16-crown-5 and 19-crown-6 derivatives, whereas 22-crown-7 derivatives showed RbィイD1+ィエD1 selectivity.4. A new type of chiral crown ether, (R, R) -2, 12-bis (hydroxymethyl) -2, 12-dimethyl-18-crown-6 possessing plural reactive functional groups, was isolated from a racemic mixture by lipase-catalyzed acetylation. The absolute configuration of the crown diol was determined based on the X-ray analysis of the complex of the derivative having plural oxyquinoline moieties with KI.5. Three kinds of positional isomers of double-armed crown ethers containing quinoline moieties in the sidearms were prepared and the participation of their sidearms in the complexation with alkali metal cations was examined. The difference in the position of the two sidearms on the crown ring was found to remarkably affect the complexation properties toward alkali metal cations when both sidearms are cis configuration to the crown ring. Less

在此螺柱中，我们可以使用doral electon-donating Earms偏离分子，将结果汇总为1。检查了碱催化阳离子的复杂性。 Catali Catali Catali terface。低对称性（例如3N-甲基 - （3n+1）-Crown-N（n = 5,6,7），并评估了它们对碱金属阳离子的剥夺。 -6个衍生物，而22个冠-7衍生物显示RBI D1+YIER D1选择性4。 - 基于x射线分析的X射线分析，以Ki.5的形式确定冠状dior的绝对构型。并检查了与金属阳离子的络合物中的颗粒。