Development of a high-speed energy-dispersive X-ray computed tomography system and its application to molecular-level imaging

高速能量色散X射线计算机断层扫描系统的研制及其在分子水平成像中的应用

基本信息

  • 批准号:
    23591791
  • 负责人:
  • 金额:
    $ 3.24万
  • 依托单位:
  • 依托单位国家:
    日本
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
  • 财政年份:
    2011
  • 资助国家:
    日本
  • 起止时间:
    2011 至 2013
  • 项目状态:
    已结题

项目摘要

In the present research, we developed an energy-dispersive X-ray computed tomography (ED-CT) system using a 25 mm/s linear CdTe scanner, a turntable, and an X-ray generator. Using this ED-CT with a maximum count rate of sub-Mcps, we performed enhanced K-edge imaging using iodine and gadolinium contrast media, and blood vessels and cancerous regions were observed at high contrast. Using the CdTe detector in conjunction with an x-y stage, we also developed a transmission-type camera, a reflection-type fluorescence camera, and a back-scattering X-ray camera. To carry out Mcps-range imaging, we developed LSO-MPPC and YAP(Ce)-MPPC detectors. Using these two detectors, we constructed the ED-CT system and performed high-speed K-edge imaging. Lately, a dual-energy comparator device was developed, and dual-energy subtraction was performed using two different energy images which were obtained simultaneously.
在本研究中,我们开发了一种能量色散 X 射线计算机断层扫描 (ED-CT) 系统,该系统使用 25 mm/s 线性 CdTe 扫描仪、转台和 X 射线发生器。使用这种具有亚Mcps最大计数率的ED-CT,我们使用碘和钆造影剂进行增强K边缘成像,并在高对比度下观察血管和癌变区域。将 CdTe 探测器与 x-y 平台结合使用,我们还开发了透射型相机、反射型荧光相机和背散射 X 射线相机。为了进行 Mcps 范围成像,我们开发了 LSO-MPPC 和 YAP(Ce)-MPPC 探测器。使用这两个探测器,我们构建了 ED-CT 系统并进行高速 K 边缘成像。最近,开发了一种双能比较器装置,利用同时获得的两个不同能量图像进行双能减影。

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
X-ray photon counting using 100 MHz ready-made silicon P-intrinsic-N X-ray diode and its application to energy-dispersive computed tomography
使用 100 MHz 现成硅 P-本征-N X 射线二极管进行 X 射线光子计数及其在能量色散计算机断层扫描中的应用
  • DOI:
  • 发表时间:
    2013
  • 期刊:
  • 影响因子:
    0
  • 作者:
    H. Kodama; M. Watanabe; E. Sato; Y. Oda; O. Hagiwara; H. Matsukiyo; A. Osawa; T. Enomoto; S. Kusachi; S. Sato; A. Ogawa
  • 通讯作者:
    A. Ogawa
High-sensitivity high-speed X-ray fluorescence scanning cadmium telluride detector for deep-portion cancer diagnosis utilizing tungsten-Ka-excited gadolinium mapping
高灵敏度高速 X 射线荧光扫描碲化镉探测器,利用钨-Ka 激发钆映射进行深部癌症诊断
  • DOI:
  • 发表时间:
    2013
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Y. Yanbe; E. Sato; H. Chiba; T. Maeda; R. Matsushita; Y. Oda; O. Hagiwara; H. Matsukiyo; A. Osawa; T. Enomoto; M. Watanabe; S. Kusachi; S. Sato; A. Ogawa
  • 通讯作者:
    A. Ogawa
Demonstration of enhanced iodine K-edge imaging using an energy-dispersive X-ray computed tomography system with a 25 mm/s-scan linear cadmium telluride detector and a single comparator
使用配备 25 毫米/秒扫描线性碲化镉探测器和单个比较​​器的能量色散 X 射线计算机断层扫描系统演示增强型碘 K 边缘成像
  • DOI:
  • 发表时间:
    2012
  • 期刊:
  • 影响因子:
    0
  • 作者:
    E. Sato; Y. Oda; A. Abudurexiti; O. Hagiwara; H. Matsukiyo; A. Osawa; T. Enomoto; M. Watanabe; S. Kusachi; S. Sato; A. Ogawa; J. Onagawa
  • 通讯作者:
    J. Onagawa
Investigation of energy-dispersive X-ray computed tomography system with CdTe scan detector and comparing-differentiator and its application to gadolinium K-edge imaging
CdTe扫描探测器和比较微分器能量色散X射线计算机断层扫描系统研究及其在钆K边缘成像中的应用
  • DOI:
  • 发表时间:
    2012
  • 期刊:
  • 影响因子:
    0
  • 作者:
    H. Chiba; Y. Sato; E. Sato; T. Maeda; R. Matsushita; Y. Yanbe; O. Hagiwara; H. Matsukiyo; A. Osawa; T. Enomoto; M. Watanabe; S. Kusachi; S. Sato; A. Ogawa; J. Onagawa
  • 通讯作者:
    J. Onagawa
Mcps-range photon-counting X-ray computed tomography system utilizing an oscillating linear-YAP(Ce) photon detector
采用振荡线性 YAP(Ce) 光子探测器的 Mcps 范围光子计数 X 射线计算机断层扫描系统
  • DOI:
  • 发表时间:
    2011
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Y. Oda; E. Sato; A. Abudurexiti; O. Hagiwara; A. Osawa; H. Matsukiyo; T. Enomoto; M. Watanabe; S. Kusachi; S. Sugimura; H. Endo; S. Sato; A. Ogawa; J. Onagawa
  • 通讯作者:
    J. Onagawa
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SATO Eiichi其他文献

Three-dimensional internal failure propagation by spherical elastic waves in fused silica glass plate subjected to hypervelocity impact of debris
碎片超高速冲击下熔融石英玻璃板中球面弹性波的三维内部失效传播
  • DOI:
    10.1299/transjsme.18-00012
  • 发表时间:
    2018
  • 期刊:
  • 影响因子:
    0
  • 作者:
    NAGANO Mikio;KAWAI Nobuaki;HASEGAWA Sunao;KITAZONO Koichi;SATO Eiichi
  • 通讯作者:
    SATO Eiichi
Three-dimensional internal failure propagation by spherical elastic waves in fused silica glass plate subjected to hypervelocity impact of debris
碎片超高速冲击下熔融石英玻璃板中球面弹性波的三维内部失效传播
  • DOI:
    10.1299/transjsme.18-00012
  • 发表时间:
    2018
  • 期刊:
  • 影响因子:
    0
  • 作者:
    NAGANO Mikio;KAWAI Nobuaki;HASEGAWA Sunao;KITAZONO Koichi;SATO Eiichi
  • 通讯作者:
    SATO Eiichi

SATO Eiichi的其他文献

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{{ truncateString('SATO Eiichi', 18)}}的其他基金

On families of rational curves and Fano varieties.
关于有理曲线族和 Fano 簇。
  • 批准号:
    22540050
  • 财政年份:
    2010
  • 资助金额:
    $ 3.24万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
Studies on novel molecular imaging using X-rays
利用 X 射线进行新型分子成像研究
  • 批准号:
    20591460
  • 财政年份:
    2008
  • 资助金额:
    $ 3.24万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
Research on rationally connected varieties
理性关联品种研究
  • 批准号:
    19540037
  • 财政年份:
    2007
  • 资助金额:
    $ 3.24万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
In situ immunological analyses of human sporadic carcinomas.
人类散发性癌的原位免疫学分析。
  • 批准号:
    19790271
  • 财政年份:
    2007
  • 资助金额:
    $ 3.24万
  • 项目类别:
    Grant-in-Aid for Young Scientists (B)
Study on Dislocation Mechanism of Ambient Temperature Creep in Hexagonal Close-packed Metals and Alloys
六方密排金属及合金环境温度蠕变位错机理研究
  • 批准号:
    18360342
  • 财政年份:
    2006
  • 资助金额:
    $ 3.24万
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
Development of high-dose-rate quasi-x-ray laser generators and applications to medical radiographies including polycapillary radiography
高剂量率准 X 射线激光发生器的开发及其在医学放射成像(包括多毛细管放射成像)中的应用
  • 批准号:
    12670902
  • 财政年份:
    2000
  • 资助金额:
    $ 3.24万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
Development of various high-intensity pulse x-ray generators by means of the high-energy discharge and applications
利用高能放电的各种高强度脉冲X射线发生器的研制及应用
  • 批准号:
    09670952
  • 财政年份:
    1997
  • 资助金额:
    $ 3.24万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
Neuropathological Study of HTLV-I Related Diseases- Adult T-cell Leukemia (ATL) and HTLV-I Associated Myelopathy (HAM)
HTLV-I 相关疾病的神经病理学研究 - 成人 T 细胞白血病 (ATL) 和 HTLV-I 相关脊髓病 (HAM)
  • 批准号:
    63570146
  • 财政年份:
    1988
  • 资助金额:
    $ 3.24万
  • 项目类别:
    Grant-in-Aid for General Scientific Research (C)

相似海外基金

High-speed high-spatial-resolution quad-energy X-ray computed tomography scanner using a CdTe array detector
使用 CdTe 阵列探测器的高速高空间分辨率四能 X 射线计算机断层扫描仪
  • 批准号:
    17K10371
  • 财政年份:
    2017
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Multimodal imaging of cancerous regions utilizing spectral X-ray CT and 7T-MRI
利用能谱 X 射线 CT 和 7T-MRI 对癌变区域进行多模态成像
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    17K01424
  • 财政年份:
    2017
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Evaluation of coronary plaque characteristics by electrocardiography-gated coronary dual-energy CT with fast tube voltage switching
快速管电压切换心电门控冠状动脉双能CT评估冠状动脉斑块特征
  • 批准号:
    15K09906
  • 财政年份:
    2015
  • 资助金额:
    $ 3.24万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
Zero-dark-counting Mcps-range X-ray detectors and their applications to high-image-quality preclinical energy-dispersive CT
零暗计数 Mcps 系列 X 射线探测器及其在高图像质量临床前能量色散 CT 中的应用
  • 批准号:
    26461804
  • 财政年份:
    2014
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Study on x-ray computed tomography with ingredient decomposing radiography by multi-variate analysis
成分分解X射线计算机断层摄影的多变量分析研究
  • 批准号:
    24360394
  • 财政年份:
    2012
  • 资助金额:
    $ 3.24万
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
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