Development of New Strategy for Analysis of Chromatographic Behavior on the Basis of Moment Theory

基于矩理论的色谱行为分析新策略的开发

• 批准号: 21350040
• 负责人: MIYABE Kanji
• 金额: $ 4.49万
• 依托单位: University of Toyama
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 2009
• 资助国家: 日本
• 起止时间: 2009 至 2011
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21350040/
• 关键词: クロマトグラフィー; 分離化学; モーメント理論

Now, various separation media having different structural characteristics of shapes and porosities, such as silica monoliths and core-shell spherical particles, are developed for improving the separation speed and efficiency of high performance liquid chromatography, which has widely been used as one of the most powerful methods for fine separation and chemical analysis. In this study, a new strateg(theory, experimental method, and data analysis procedure) was developed for quantitatively analyzing the separation properties and mechanisms of the different packing materials in detail. The strategy can provide new information about chromatographic behavior, which cannot be derived by conventional theories and models, such as the rate theory of chromatography.

现在，为了提高高效液相色谱的分离速度和效率，开发了具有不同形状和孔隙率结构特征的各种分离介质，例如二氧化硅整体和核壳球形颗粒，高效液相色谱已被广泛用作最重要的分离介质之一。用于精细分离和化学分析的强大方法。在本研究中，开发了一种新的策略（理论、实验方法和数据分析程序）来详细定量分析不同填料的分离特性和机理。该策略可以提供有关色谱行为的新信息，这是传统理论和模型（例如色谱速率理论）无法得出的。

项目成果

Moment Analysis of Chromatographic Behavior of Superficially Porous Particles

表面多孔颗粒色谱行为的矩分析

• 发表时间: 2011
• 作者: Miyabe; K.;Noiri; K.;Kobayashi; K
• 通讯作者: K

External Mass Transfer in Silica Monolithic Stationary Phases

二氧化硅整体固定相中的外部传质

• 发表时间: 2010
• 作者: Miyabe; K.;Ando; N.;Nakamura; T.;Guiochon; G
• 通讯作者: G

An Estimation of the Column Efficiency Made by Analyzing Tailing Peak Profile

通过分析尾矿峰轮廓估算塔效率

• 发表时间: 2009
• 作者: Miyabe; K.;Matsumoto; Y.;Niwa; Y.;Ando; N.;Guiochon; G
• 通讯作者: G

Peak Parking Method for Measurement of Molecular Diffusivity in Liquid Phase Systems

用于测量液相系统中分子扩散率的峰停放法

• 发表时间: 2009
• 作者: Miyabe; K.;Ando; N.;Guiochon; G
• 通讯作者: G

Peak Parking-Moment Analysis Method for the Measurement of Surface Diffusion Coefficient

表面扩散系数测量的峰值停车力矩分析方法

• 发表时间: 2009
• 作者: Miyabe; K.;Matsumoto; Y.;Ando; N
• 通讯作者: N