High functionalization of macrocyclic host compounds based on dynamic octadentate cyclen-metal complexes

基于动态八齿环-金属配合物的大环主体化合物的高功能化

• 批准号: 24750133
• 负责人: ITO Hiroshi
• 金额: $ 2.91万
• 依托单位: Osaka City University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2012
• 资助国家: 日本
• 起止时间: 2012-04-01 至 2014-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24750133/
• 关键词: 超分子化学; 金属錯体; サイクレン; 分子認識; 構造有機化学; キラリティー; ランタノイド; ナトリウム

A series of macrotricyclic host compounds based on two octadentate cyclen-metal complexes was synthesized and applied for the recognition of guest anions using the internal cavity. The dinuclear complexes dynamically changed their molecular structures depending on solvent, side chains, and guest molecules. Especially, molecular recognitions by sodium complex was firstly achieved by using a sophisticatedly designed disodium complex. Chirality recognition of guest anions by chiral di-lanthanoid complexes was detected by the difference of emission intensity of the lanthanoid cations, which can be distinguished by naked eyes in some cases. We also developed two novel methods for the control of molecular dynamics of octadentate cyclen-metal complexes: a bimodal control of molecular dynamics, and reversible molecular switching using organic reactions.

合成了一系列基于两个基于两个圆锥形的基因组合络合物的宏观宿主化合物，并应用了使用内部腔体识别来宾阴离子的识别。双核复合物根据溶剂，侧链和客体分子动态改变了分子结构。特别是，首先使用精致设计的二钠复合物来实现钠复合物的分子识别。通过手性二叶lanthanoid络合物对宾客阴离子的手性识别是通过灯笼阳离子阳离子的发射强度差异检测的，在某些情况下可以通过肉眼来区分。我们还开发了两种新方法，用于控制八度旋转凝乳 - 金属复合物的分子动力学：分子动力学的双峰控制，以及使用有机反应的可逆分子转换。

项目成果

Chirality Transfer in Propeller-Shaped Cyclen―Calcium(II) Complexes: Metal-Coordinating and Ion-Pairing Anion ProtocolsProcedures

螺旋桨状 Cyclen—钙 (II) 配合物中的手性传递：金属配位和离子对阴离子方案程序

• DOI: 10.1002/chem.201204323
• 发表时间: 2012
• 期刊: Chemistry -A European Journal
• 作者: Hiroshi Ito;Hiroshi Tsukube;Satoshi Shinoda
• 通讯作者: Satoshi Shinoda

A chirality rewriting cycle mediated by a dynamic cyclen-calcium complex.

• DOI: 10.1039/c2cc35350d
• 发表时间: 2012-10
• 期刊: Chemical communications
• 影响因子: 4.9
• 作者: Hiroshi Ito;H. Tsukube;S. Shinoda

Publication

• DOI: 10.1007/bf03191973
• 发表时间: 2010
• 期刊: Mycotoxin Research
• 影响因子: 3

Chirality Transfer in Propeller-Shaped Cyclen–Calcium(II) Complexes : Metal-Coordinating and Ion-Pairing Anion Procedures

螺旋桨状 Cyclen-钙 (II) 配合物中的手性传递：金属配位和离子对阴离子程序

• 发表时间: 2013
• 期刊: Chem.–Eur. J.
• 作者: Ito;H.; Tsukube;H.; Shinoda;S.
• 通讯作者: S.

機能化学研究室

功能化学实验室