High functionalization of macrocyclic host compounds based on dynamic octadentate cyclen-metal complexes

基于动态八齿环-金属配合物的大环主体化合物的高功能化

• 批准号: 24750133
• 负责人: ITO Hiroshi
• 金额: $ 2.91万
• 依托单位: Osaka City University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2012
• 资助国家: 日本
• 起止时间: 2012-04-01 至 2014-03-31
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24750133/
• 关键词: 超分子化学; 金属錯体; サイクレン; 分子認識; 構造有機化学; キラリティー; ランタノイド; ナトリウム

A series of macrotricyclic host compounds based on two octadentate cyclen-metal complexes was synthesized and applied for the recognition of guest anions using the internal cavity. The dinuclear complexes dynamically changed their molecular structures depending on solvent, side chains, and guest molecules. Especially, molecular recognitions by sodium complex was firstly achieved by using a sophisticatedly designed disodium complex. Chirality recognition of guest anions by chiral di-lanthanoid complexes was detected by the difference of emission intensity of the lanthanoid cations, which can be distinguished by naked eyes in some cases. We also developed two novel methods for the control of molecular dynamics of octadentate cyclen-metal complexes: a bimodal control of molecular dynamics, and reversible molecular switching using organic reactions.

合成了一系列基于两个八齿环烯-金属配合物的大三环主体化合物，并应用于利用内腔识别客体阴离子。双核配合物根据溶剂、侧链和客体分子动态改变其分子结构。特别是，钠络合物的分子识别首次通过使用精心设计的二钠络合物实现。手性二镧系配合物对客体阴离子的手性识别是通过镧系阳离子发射强度的差异来检测的，在某些情况下可以用肉眼区分。我们还开发了两种控制八齿循环金属配合物分子动力学的新方法：分子动力学的双峰控制和使用有机反应的可逆分子转换。

项目成果

Publication

• DOI: 10.1007/bf03191973
• 发表时间: 2010
• 期刊: Mycotoxin Research
• 影响因子: 3

Chirality Transfer in Propeller-Shaped Cyclen―Calcium(II) Complexes: Metal-Coordinating and Ion-Pairing Anion ProtocolsProcedures

螺旋桨状 Cyclen—钙 (II) 配合物中的手性传递：金属配位和离子对阴离子方案程序

• DOI: 10.1002/chem.201204323
• 发表时间: 2012
• 期刊: Chemistry -A European Journal
• 作者: Hiroshi Ito;Hiroshi Tsukube;Satoshi Shinoda
• 通讯作者: Satoshi Shinoda

Chirality Transfer in Propeller-Shaped Cyclen–Calcium(II) Complexes : Metal-Coordinating and Ion-Pairing Anion Procedures

螺旋桨状 Cyclen-钙 (II) 配合物中的手性传递：金属配位和离子对阴离子程序

• 发表时间: 2013
• 期刊: Chem.–Eur. J.
• 作者: Ito;H.; Tsukube;H.; Shinoda;S.
• 通讯作者: S.

機能化学研究室

功能化学实验室

Development of macrocyclic host molecules based on dynamic octadentate cyclen-metal complexes

基于动态八齿环-金属配合物的大环主体分子的开发

• 发表时间: 2014
• 作者: Hiroshi Ito;Satoshi Shinoda
• 通讯作者: Satoshi Shinoda