Study on high-precision carbon-ion treatment for tumors with respiratory motion by 4-dimensional treatment planning

4维治疗计划高精度碳离子治疗呼吸运动肿瘤的研究

• 批准号: 23791397
• 负责人: TASHIRO Mutsumi
• 金额: $ 1.58万
• 依托单位: Gunma University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011 至 2012
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23791397/
• 关键词: 放射線治療; 粒子線治療; 4D CT; 治療計画; 呼吸性移動; 線量分布; 重粒子線治療; 呼吸同期照射; 4D-CT; 4次元治療計画; 放射線治療; 粒子線治療; 4D CT; 治療計画; 呼吸性移動; 線量分布; 重粒子線治療; 呼吸同期照射; 4D-CT; 4次元治療計画

The system environment has been created, which can deal with actual clinical CT data using a deformable fusion (registration) software for the respiratory motion evaluation with 4DCT images. A treatment-planning support tool has been also installed to be able to calculate dose distributions for a number of 3DCT images (4DCT image) at one time with an identical treatment plan condition. By use of these tools, accumulated dose distributions could be derived for CT images with different patient positions and/or with respiratory motion and deformation by considering such motion and deformation. Target dose coverage with motion and deformation could be evaluated.

已经创建了系统环境，可以使用4DCT图像的呼吸运动评估使用可变形的融合（注册）软件来处理实际的临床CT数据。还已经安装了一种治疗计划支持工具，以便一次以相同的治疗计划条件计算许多3DCT图像（4DCT图像）的剂量分布。通过使用这些工具，可以为具有不同患者位置和/或具有呼吸运动和变形的CT图像得出积累的剂量分布，通过考虑这种运动和变形。可以评估具有运动和变形的目标剂量覆盖范围。