The effect of antimicrobial with hand surface immune materials to prevent appearance the drug resistant bacteria

手表免疫材料抗菌预防耐药菌出现的效果

• 批准号: 23593142
• 负责人: ARAKAWA Mitsue
• 金额: $ 3.24万
• 依托单位: Oita University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2011
• 资助国家: 日本
• 起止时间: 2011 至 2013
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-23593142/
• 关键词: 手指衛生; 薬剤耐性菌; 免疫; サイトカイン; 看護師; 医療関連感染; 標準予防策; 手指衛生; 薬剤耐性菌; 免疫; サイトカイン; 看護師; 医療関連感染; 標準予防策

The purpose of this study is the interaction between immune function of the hand surface and commensal bacteria. Hand washing samples from 27 volunteers were harvested before and after hand washing (water hand washing or hand washing with liquid soap). The samples were assumed including bacteria and immune substances like cytokine and immune globulin from hand. Regards to pre-examination, these sample were assayed about 5 immune materials, the 3 material; Immune globulin, IL-1a and IL-1b were detected. These values were varied in individual, laterality and kind of hand washing. These samples were assayed about inhibition of coagulase negative Staphylococcus spp. growth. But inhibition effect was not detected clearly.

这项研究的目的是手表面的免疫功能与共生细菌之间的相互作用。洗手之前和之后，从27名志愿者那里收获了洗手样品（用液体肥皂洗洗或洗手）。假定样品包括细菌和免疫物质，例如细胞因子和免疫球蛋白。关于预调查，对这些样品进行了约5种免疫材料，即3种材料；检测到免疫球蛋白，IL-1A和IL-1B。这些价值在个体，横向和洗手性上有所不同。分析了这些样品抑制凝固酶阴性葡萄球菌属。生长。但是没有清楚地检测到抑制作用。