Ca surface modification gives osteoconductivity to ceramics of high mechanical property

Ca表面改性赋予高机械性能陶瓷骨传导性

• 批准号: 22791894
• 负责人: TARIQUE A. a.
• 金额: $ 2.58万
• 依托单位: Kyushu University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2010
• 资助国家: 日本
• 起止时间: 2010 至 2011
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22791894/
• 关键词: アルミナ; 表面改質; 骨伝導性; セラミックス

We examined whether Ca surface modification ranging from molecular to nano order level gave osteoconductivity to ceramics with high mechanical property. As a result of optimization for treatment condition, it was appeared that much Ca ions could be immobilized onto alumina substrate when hydrothermallytreated at 125℃in the presence of 50 mmol^-1 CaC1^2 solution for 7 days. The treated alumina substrate showed spontaneous apatite deposition in simulated body fluid. Response to rat bone marrow cell was investigated so that the response on the treated alumina substrate was significantly higher than those on nontreated alumina substrate.

我们检查了CA表面修饰是否从分子到纳米顺序水平，对具有高机械性能的陶瓷具有破骨传导率。由于对治疗条件进行了优化，似乎在50 mmol^-1 cac1^2溶液存在7天的情况下，在125℃下氢化时，可以将许多CA离子固定在氧化铝底物上。处理过的氧化铝底物在模拟体液中显示出赞助的磷灰石沉积。研究了对大鼠骨髓细胞的反应，以便对处理过的氧化铝底物的反应明显高于非固化氧化铝底物的反应。

项目成果

Kanji Tsuru, Michito Maruta, Akari Takeuchi, Shigeki Matsuya, Yoshihiro Terada and Kunio Ishikawa : In vitro osteoconductivity evaluation of alumina treated hydrothermally inCaCl^2 solution

Kanji Tsuru、Michito Maruta、Akari Takeuchi、Shigeki Matsuya、Yoshihiro Terada 和 Kunio Ishikawa：CaCl^2 溶液中水热处理的氧化铝的体外骨传导性评估

• 发表时间: 2010
• 期刊: Journal of the Ceramic Society of Japan
• 影响因子: 1.1
• 作者: KAJIHARA S,DOI K;KUBO T;OUE H;MATSUURA A;MORITA K;TAKESHITA R. ASAMORI C;AKAGAWA Y;Abdullah Al-Mahmoodd Tariciue
• 通讯作者: Abdullah Al-Mahmoodd Tariciue