The influence of immediate loading on bone around titanium implants with different surface topographies

即刻加载对不同表面形貌钛种植体周围骨的影响

• 批准号: 21791876
• 负责人: SATO Naoko
• 金额: $ 2.75万
• 依托单位: Tohoku University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2009
• 资助国家: 日本
• 起止时间: 2009 至 2010
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21791876/
• 关键词: 早期荷重; インプラント表面性状; 骨結合

To examine the interactive effects of mechanical loading and titanium surface topography on bone formation around immediately loaded implants, bone with loaded soomth(Sm) and acid-etched (AE) implants in rats were scanned by micro-CT system and removable torque test was performed. The loaded AE implants showed significantly decreased in bone mineral density of cortical bone at week 4 and contact surface area between cortical bone and the implant at week 2 compared to those for unloaded AE implants. The removable torque values for loaded Sm implants at week 1 was significantly lower than that for unloaded Sm implants although the loading didn't affect the biomechanical strength for AE implants. These suggested that different surface topography differently affected bone responses around immediately loaded implants.

为了检查机械载荷和钛表面地形对立即植入物周围的骨形成的相互作用，通过微型CT系统扫描了大鼠中带有负载的（SM）和酸蚀刻（AE）植入物的骨骼，并进行了可移动的扭矩测试。 。与卸载的AE植入物相比，在第4周的皮质骨骨矿物质密度和植入物之间的接触表面积显着降低，与卸载的AE植入物相比，皮质骨矿物质密度显着降低。在第1周，已加载的SM植入物的可移动扭矩值明显低于未加载的SM植入物的扭矩值，尽管负载并不影响AE植入物的生物力学强度。这些表明，不同的表面形貌对立即加载的植入物周围的骨反应有所不同。

项目成果

Age-dependent Degradation of the Protein Adsorption Capacity of Titanium

• DOI: 10.1177/0022034509339567
• 发表时间: 2009-07-01
• 期刊: JOURNAL OF DENTAL RESEARCH
• 影响因子: 7.6
• 作者: Hori, N.;Att, W.;Ogawa, T.
• 通讯作者: Ogawa, T.

N-acetyl cysteine alleviates cytotoxity of bone substitute.

N-乙酰半胱氨酸减轻骨替代物的细胞毒性。

• 发表时间: 2010
• 期刊: J Dental Research
• 作者: Yamada M;Ueno T;Minamikawa;Sato N;Ogawa.T
• 通讯作者: Ogawa.T

N-acetyl cysteine alleviate cytotoxity of bone substitute

N-乙酰半胱氨酸减轻骨替代物的细胞毒性

• 发表时间: 2010
• 期刊: J Dental Res. 89
• 作者: Yamada M;Ueno T;Minamikawa T;Sato N;Ogawa T
• 通讯作者: Ogawa T