Analysis of non-olfactory sensory pathways that are necessary for the olfactory associative learning of the Drosophila mushroom body

果蝇蘑菇体嗅觉联想学习所需的非嗅觉感觉通路分析

基本信息

  • 批准号:
    21300117
  • 负责人:
  • 金额:
    $ 12.23万
  • 依托单位:
  • 依托单位国家:
    日本
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
  • 财政年份:
    2009
  • 资助国家:
    日本
  • 起止时间:
    2009 至 2011
  • 项目状态:
    已结题

项目摘要

The mushroom body is known to be an important center for associative olfactory memory in the insect brain. To understand the neural pathways of information other than the olfactory signals toward this center, we first analyzed the organization of the primary gustatory center, whose structure was hardly known despite the importance of gustatory information in associative olfactory learning. We also analyzed the neural connections of the brain regions that receive the arborizations of the input/output neurons of the mushroom body. By systematically labeling neurons according to cell lineage, we found that no neurons from the gustatory, auditory and visual centers directly project to these regions and that there are distinct regions that receive the projections from putative higher-associative centers.
众所周知,蘑菇体是昆虫大脑中联想嗅觉记忆的重要中心。为了了解除嗅觉信号之外的信息通往该中心的神经通路,我们首先分析了初级味觉中枢的组织,尽管味觉信息在联想嗅觉学习中很重要,但其结构却几乎不为人所知。我们还分析了接收蘑菇体输入/输出神经元分支的大脑区域的神经连接。通过根据细胞谱系系统地标记神经元,我们发现来自味觉、听觉和视觉中心的神经元没有直接投射到这些区域,并且有不同的区域接收来自假定的高级联想中心的投射。

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Comprehensive analysis of the neural network in Drosophila brain on the neuroblast lineages
果蝇大脑神经网络对神经母细胞谱系的综合分析
  • DOI:
  • 发表时间:
    2010
  • 期刊:
  • 影响因子:
    0
  • 作者:
    伊藤正芳;遠藤啓太;伊藤啓
  • 通讯作者:
    伊藤啓
Chromatin modification of Notch targets in olfactory receptor neuron diversification
  • DOI:
    10.1038/nn.2998
  • 发表时间:
    2012-02-01
  • 期刊:
  • 影响因子:
    25
  • 作者:
    Endo, Keita;Karim, M. Rezaul;Moore, Adrian W.
  • 通讯作者:
    Moore, Adrian W.
Understanding the brain composition from the viewpoint of cell lineage
从细胞谱系的角度理解大脑的组成
  • DOI:
  • 发表时间:
    2010
  • 期刊:
  • 影响因子:
    0
  • 作者:
    伊藤啓;遠藤啓太;粟崎健;伊藤正芳
  • 通讯作者:
    伊藤正芳
Projectome mapping of neural circuits in the Drosophila brain based on the neuroblast lineages
基于神经母细胞谱系的果蝇大脑神经回路的投影组图谱
  • DOI:
  • 发表时间:
    2011
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Y.Yasaka;M.L.Klein;M.Nakahara;N.Matubayasi;青山和裕;伊藤正芳,遠藤啓太,伊藤啓
  • 通讯作者:
    伊藤正芳,遠藤啓太,伊藤啓
Olfactory Receptor Neuron Identity is Diversified by the Drosophila Evi1/Prdm16 Homologue Hamlet that Mediates Chromatin Modification at Notch-Target Loci
果蝇 Evi1/Prdm16 同源哈姆雷特介导 Notch 靶位点染色质修饰,使嗅觉受体神经元身份多样化
  • DOI:
  • 发表时间:
    2011
  • 期刊:
  • 影响因子:
    0
  • 作者:
    遠藤啓太;MD Rezaul Karim;Alena Krejci;Emi Kinameri;Hiroaki Taniguchi;Matthias Siebert,伊藤啓;Sarah J. Bray;Adrian W. Moore
  • 通讯作者:
    Adrian W. Moore
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ITO Kei其他文献

ITO Kei的其他文献

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{{ truncateString('ITO Kei', 18)}}的其他基金

Pathogenic roles of collagen XVII in migration of basal keratinocytes
XVII 胶原蛋白在基底角质形成细胞迁移中的致病作用
  • 批准号:
    24591619
  • 财政年份:
    2012
  • 资助金额:
    $ 12.23万
  • 项目类别:
    Grant-in-Aid for Scientific Research (C)
Establishment of the general principle of color universal design based on the color recognition characteristics of colorblind and low-vision people
基于色盲、弱视人群色彩识别特征建立色彩通用设计总原则
  • 批准号:
    23650161
  • 财政年份:
    2011
  • 资助金额:
    $ 12.23万
  • 项目类别:
    Grant-in-Aid for Challenging Exploratory Research
Therapeutic study for epidermolysis bullosa using milk with human collagen VII
含人VII胶原蛋白牛奶治疗大疱性表皮松解症的治疗研究
  • 批准号:
    22791047
  • 财政年份:
    2010
  • 资助金额:
    $ 12.23万
  • 项目类别:
    Grant-in-Aid for Young Scientists (B)
Analysis of the gene therapy for epidermolysis bullosa using transgenic rescue experiments of the disease model mice
大疱性表皮松解症模型小鼠转基因拯救实验分析基因治疗
  • 批准号:
    20790781
  • 财政年份:
    2008
  • 资助金额:
    $ 12.23万
  • 项目类别:
    Grant-in-Aid for Young Scientists (B)
Development of non-curriculum-based test questions evaluating comprehensive linguistic performance
开发评估综合语言表现的非课程测试题
  • 批准号:
    20700659
  • 财政年份:
    2008
  • 资助金额:
    $ 12.23万
  • 项目类别:
    Grant-in-Aid for Young Scientists (B)
Systematic analysis of the neural circuits in the higher visual centers of the Drosophila brain
果蝇大脑高级视觉中心神经回路的系统分析
  • 批准号:
    18370060
  • 财政年份:
    2006
  • 资助金额:
    $ 12.23万
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
Systematic analysis of the neural circuits connecting the lower-order sensory neuropils and higher-order integrative regions of the Drosophila brain
连接果蝇大脑低阶感觉神经元和高阶整合区域的神经回路的系统分析
  • 批准号:
    12480205
  • 财政年份:
    2000
  • 资助金额:
    $ 12.23万
  • 项目类别:
    Grant-in-Aid for Scientific Research (B)
A Study on the Teachers Professinal Development and their Net-work from Life-Course Approach.
生命课程视角下教师专业发展及其网络研究。
  • 批准号:
    03451043
  • 财政年份:
    1991
  • 资助金额:
    $ 12.23万
  • 项目类别:
    Grant-in-Aid for General Scientific Research (B)

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多巴胺能神经元气味表征的神经机制取决于内部状态
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牛植被辨别能力评价及动物友好型放牧草地创建与评价
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Perception of Flavor Quality: Multisensory and Cognitive Processes
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