Can Occlusal Evaluation Determinate Future Maxillofacial Morphology of Children with Unilateral Cleft Lip and Palate?

咬合评估能否确定单侧唇腭裂儿童未来的颌面形态？

• 批准号: 21592598
• 负责人: SUZUKI Akira
• 金额: $ 3.08万
• 依托单位: Kyushu University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2009
• 资助国家: 日本
• 起止时间: 2009 至 2011
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21592598/
• 关键词: 口唇裂口蓋裂患者; 咬合評価; 顎顔面形態; 成長; Goslon Yardstick; 継年資料; セファロ分析; 石膏模型; 口唇裂口蓋裂; 顎顔面成長; 頭部X線規格写真; 経年的研究; 歯学; 臨床; 顎顔面発育; Goslon yardstic; 5-year-old index

Two studies were carried out ;(Study A) Correlation analyses between the occlusal relationship evaluated by the Goslon Yardstick and the maxillofacial growth measured from longitudinal cephalographs taken on 85 subjects with unilateral cleft lip and palate at the ages of five, ten, and over fifteen.(Study B) Comparison of maxillofacial growth patterns from 3-4 months old to fifteen years or older taken on longitudinal cephalographs of 38 male and 46 female CLP subjects among three cleft types ; unilateral cleft lip and alveolus(CLA), unilateral cleft lip and palate(CLP), and isolated cleft palate(CP). The followings were concluded from these two studies(1) Occlusal evaluation by the Five-year-old index or the Goslon Yardstick is a simple measure to represent maxilla-mandibular relationship, but those measures evaluate the outcome of maxillofacial growth until the time.(2) The occlusal evaluation by the Goslon Yardstick at ten years was similar with the one by the Five-year-old index at … More five years, furthermore orthodontic treatment has a tendency to make the outcome of occlusal evaluation better.(3) The outcome of occlusal evaluation has a significant relation with the amount and direction of mandibular growth rather than maxillary growth affected by labioplasty and/or palatoplasty in the subjects with unilateral cleft lip and palate.(4) Occlusal outcome evaluated by the Goslon Yardstick at the age of ten had no significant relation with future maxillofacial growth after then until adulthood. This suggests the maxillofacial growth in puberty may be great and determined the matured facial profile in adult. In this study, there were some CLP subjects who had been classified in good groups by the five-year-old index and the Goslon Yardstick, but underwent Orthognathic surgery in adulthood.(5) From the Study B comparing the longitudinal maxillofacial growth among the subjects with CLA, CLP, and CP, both labial and palatal plastic surgeries affected maxillofacial growth, but not mandibular growth. As our surgical procedure for palatal repair was the same one, the modified V-Y push back method, the effects of surgical procedures on maxillofacial growth will be evaluated and compared by the inter-centers study in future.(6) This study suggests that final maxillofacial morphology in adulthood will be determined by the genetic growth potential of the growing CLP children, especially in puberty. We need to evaluate the effects of more factors ; ones by plastic surgeries, genetic background, in order to predict the matured maxillofacial growth of the subjects with cleft lip and/or palate. Less

进行了两项研究；（研究 A）对 85 名年龄在 5 岁、10 岁和 15 岁以上的单侧唇裂和腭裂受试者进行了 Goslon Yardstick 评估的咬合关系与纵向头颅照片测量的颌面生长之间的相关性分析(研究 B) 纵向头颅照片上 3-4 个月大至 15 岁或以上颌面生长模式的比较38 名男性和 46 名女性 CLP 受试者分为三种类型：单侧唇腭裂（CLA）、单侧唇腭裂（CLP）和孤立性腭裂（CP）。这两项研究得出以下结论：（1）咬合。五岁指数或 Goslon Yardstick 的评估是表示上颌-下颌关系的简单衡量标准，但这些衡量标准评估的是（2）十年时用Goslon Yardstick进行的咬合评估与五年时的五岁指数评估相似，而且正畸治疗有使咬合结果发生变化的趋势。 (3)咬合评估的结果与下颌生长的数量和方向有显着关系，而不是与阴唇整形术和/或影响的上颌生长有显着关系。 (4) 十岁时用 Goslon Yardstick 评估的咬合结果与此后直至成年后的颌面部生长没有显着关系。在这项研究中，确定了成年人成熟的面部轮廓，一些 CLP 受试者已根据五岁指数和 Goslon Yardstick 被分类为良好组， (5)从比较CLA、CLP和CP受试者的纵向颌面部生长的研究B来看，唇整形手术和腭整形手术均影响颌面部生长，但不影响下颌生长。腭修复术同样采用改良V-Y推回法，手术对颌面部生长的影响将通过2017年的中心间研究进行评价和比较。 (6) 这项研究表明，成年期的最终颌面形态将由成长中的 CLP 儿童的遗传生长潜力决定，特别是在青春期，我们需要评估更多因素的影响；包括整形手术、遗传背景、以便预测唇裂和/或腭裂受试者的成熟颌面生长。

项目成果

口唇裂口蓋裂患者における顎顔面発育の乳幼児期から成人までの経年的変化

唇腭裂患者从婴儿期到成年期颌面发育的长期变化

• 发表时间: 2011
• 作者: Suzuki A;Yoshizaki K;Honda Y;Sasaguri M;Kubota Y;Nakamura N;Ohishi M;Oka M;Tashiro H;Katsuki T;Fujino H.;田村直子,笹栗正明,鈴木陽,光安岳志,辻口友美,新井伸作,松村香織,森悦秀,中村誠司
• 通讯作者: 田村直子,笹栗正明,鈴木陽,光安岳志,辻口友美,新井伸作,松村香織,森悦秀,中村誠司

Retrospective Evaluation of Treatment Outcome in Japanese Children with Complete Unilateral Cleft Lip and Palate

日本完全性单侧唇腭裂儿童治疗效果的回顾性评价

• 发表时间: 2007
• 期刊: Part 1 : 5 Year Olds' Index for Dental Arch Relationships. Cleft Palate-Craniofac J
• 作者: Suzuki A;Yoshizaki K;Honda Y;Sasaguri M;Kubota Y;Nakamura N;Ohishi M;Oka M;Tashiro H;Katsuki T;Fujino H.
• 通讯作者: Fujino H.