Can Occlusal Evaluation Determinate Future Maxillofacial Morphology of Children with Unilateral Cleft Lip and Palate?

咬合评估能否确定单侧唇腭裂儿童未来的颌面形态？

• 批准号: 21592598
• 负责人: SUZUKI Akira
• 金额: $ 3.08万
• 依托单位: Kyushu University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2009
• 资助国家: 日本
• 起止时间: 2009 至 2011
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-21592598/
• 关键词: 口唇裂口蓋裂患者; 咬合評価; 顎顔面形態; 成長; Goslon Yardstick; 継年資料; セファロ分析; 石膏模型; 口唇裂口蓋裂; 顎顔面成長; 頭部X線規格写真; 経年的研究; 歯学; 臨床; 顎顔面発育; Goslon yardstic; 5-year-old index

Two studies were carried out ;(Study A) Correlation analyses between the occlusal relationship evaluated by the Goslon Yardstick and the maxillofacial growth measured from longitudinal cephalographs taken on 85 subjects with unilateral cleft lip and palate at the ages of five, ten, and over fifteen.(Study B) Comparison of maxillofacial growth patterns from 3-4 months old to fifteen years or older taken on longitudinal cephalographs of 38 male and 46 female CLP subjects among three cleft types ; unilateral cleft lip and alveolus(CLA), unilateral cleft lip and palate(CLP), and isolated cleft palate(CP). The followings were concluded from these two studies(1) Occlusal evaluation by the Five-year-old index or the Goslon Yardstick is a simple measure to represent maxilla-mandibular relationship, but those measures evaluate the outcome of maxillofacial growth until the time.(2) The occlusal evaluation by the Goslon Yardstick at ten years was similar with the one by the Five-year-old index at … More five years, furthermore orthodontic treatment has a tendency to make the outcome of occlusal evaluation better.(3) The outcome of occlusal evaluation has a significant relation with the amount and direction of mandibular growth rather than maxillary growth affected by labioplasty and/or palatoplasty in the subjects with unilateral cleft lip and palate.(4) Occlusal outcome evaluated by the Goslon Yardstick at the age of ten had no significant relation with future maxillofacial growth after then until adulthood. This suggests the maxillofacial growth in puberty may be great and determined the matured facial profile in adult. In this study, there were some CLP subjects who had been classified in good groups by the five-year-old index and the Goslon Yardstick, but underwent Orthognathic surgery in adulthood.(5) From the Study B comparing the longitudinal maxillofacial growth among the subjects with CLA, CLP, and CP, both labial and palatal plastic surgeries affected maxillofacial growth, but not mandibular growth. As our surgical procedure for palatal repair was the same one, the modified V-Y push back method, the effects of surgical procedures on maxillofacial growth will be evaluated and compared by the inter-centers study in future.(6) This study suggests that final maxillofacial morphology in adulthood will be determined by the genetic growth potential of the growing CLP children, especially in puberty. We need to evaluate the effects of more factors ; ones by plastic surgeries, genetic background, in order to predict the matured maxillofacial growth of the subjects with cleft lip and/or palate. Less

进行了两项研究；（研究A）通过Goslon Yardstick评估的咬合关系与对85名单侧裂口和唇酸盐对85名受试者进行的纵向头皮造影测量的上颌面生长之间的相关性分析，该年龄是五个年龄，十个年龄，比较旧的。在三种裂口类型中，在38名男性和46名女性CLP受试者的纵向头摄影仪上；单侧lip裂和肺泡（CLA），单侧lip裂（CLP）以及孤立的裂口（CP）。从这两项研究（1）五岁的指数或Goslon Yardstick的咬合评估得出的结论是一项简单的措施，是代表上颌层间关系的一种简单措施，但是这些措施评估了颌面增长的结果，直到当时的颌面评估。正畸治疗倾向于使咬合评估的结果更好。（3）咬合评估的结果与下颌骨生长的数量和方向有显着的关系，而不是由唇骨和/或palat骨的近距离成形术和/或palatoptasts的上颌骨成形术的量和/或pal骨的影响。在此之后直到成年后，与未来的颌面增长有显着关系。这表明青春期的上颌面生长可能很棒，并确定了成人成熟的面部特征。 In this study, there were some CLP subjects who had been classified in good groups by the five-year-old index and the Goslon Yardstick, but underwent Orthognathic surgery in adulthood.(5) From the Study B comparing the longitudinal maxillofacial growth among the subjects with CLA, CLP, and CP, both labial and palatal plastic surgeries affected maxillofacial growth, but not mandibular growth.由于我们对pala骨修复的手术程序是相同的，因此修改了V-Y推回方法，将来将评估手术程序对上颌面生长的影响，并通过中心研究中的研究中的研究进行比较。（6）这项研究表明，最终的上颌面形性形态在成长中的遗传增长将在成长中成长的clp Clppy中，尤其是Pupulberty ppulberty确定。我们需要评估更多因素的影响；通过塑料手术，遗传背景，以预测受试者的成熟唇唇和/或口感的成熟。较少的

项目成果

口唇裂口蓋裂患者における顎顔面発育の乳幼児期から成人までの経年的変化

唇腭裂患者从婴儿期到成年期颌面发育的长期变化

• 发表时间: 2011
• 作者: Suzuki A;Yoshizaki K;Honda Y;Sasaguri M;Kubota Y;Nakamura N;Ohishi M;Oka M;Tashiro H;Katsuki T;Fujino H.;田村直子,笹栗正明,鈴木陽,光安岳志,辻口友美,新井伸作,松村香織,森悦秀,中村誠司
• 通讯作者: 田村直子,笹栗正明,鈴木陽,光安岳志,辻口友美,新井伸作,松村香織,森悦秀,中村誠司

Retrospective Evaluation of Treatment Outcome in Japanese Children with Complete Unilateral Cleft Lip and Palate

日本完全性单侧唇腭裂儿童治疗效果的回顾性评价

• 发表时间: 2007
• 期刊: Part 1 : 5 Year Olds' Index for Dental Arch Relationships. Cleft Palate-Craniofac J
• 作者: Suzuki A;Yoshizaki K;Honda Y;Sasaguri M;Kubota Y;Nakamura N;Ohishi M;Oka M;Tashiro H;Katsuki T;Fujino H.
• 通讯作者: Fujino H.