Bidirectional approach with neurotrophic factors for the acceleration of neuro-regeneration.

使用神经营养因子的双向方法加速神经再生。

• 批准号: 20390411
• 负责人: SAITO Shigeru
• 金额: $ 7.49万
• 依托单位: Gunma University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 2008
• 资助国家: 日本
• 起止时间: 2008 至 2010
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20390411/
• 关键词: 疼痛管理学; 再生医学; 栄養因子; 痙痛管理学

For the better recovery of damaged neurons, cellular environment seems to be crucial. In the present study, the authors assessed effects of neurotrophic factors in various settings. As the results, it was revealed that normo-glycemia is the best condition for the neuro-regeneration. Newly developed drug delivery system was identified as effective for gradual release of nerve activity controlling drugs.

为了更好地恢复受损的神经元，细胞环境似乎至关重要。在本研究中，作者评估了各种环境中神经营养因素的影响。结果，结果表明，正常血糖是神经再生的最佳状况。新开发的药物输送系统可有效地逐渐释放控制药物的神经活动。

项目成果

CTガイド下神経ブロック

CT引导神经阻滞

• 发表时间: 2011
• 作者: 関本研一;他;関本研一;関本研一;齋藤繁
• 通讯作者: 齋藤繁

Thermal hyperalgeria via supraspinal mechanisms in mice lacking glutamate decarboxylase 65

缺乏谷氨酸脱羧酶的小鼠通过脊髓上机制引起热过敏65

• 发表时间: 2009
• 期刊: J Pharmacol Exp Ther Vol.331(1)
• 作者: Kubo K;Nishikawa K;Hardy-Yamada M;Ishizeki J;Yanagawa Y;Saito S;Kubo K
• 通讯作者: Kubo K

Anatomic analysis of computed tomography images obtained during fluoroscopic computed tomography-guided percutaneous lumbar symnathectomy.

对荧光计算机断层扫描引导经皮腰椎交感神经切除术期间获得的计算机断层扫描图像进行解剖分析。

• 发表时间: 2008
• 期刊: Journal of Anesthesia 22
• 作者: Koizuka S;Saito S;Obata H;robe M;Koyama Y;Takahashi A.
• 通讯作者: Takahashi A.

The radiobiological effectiveness of carbon-ion beams on growing neurons

• DOI: 10.1080/09553000903020032
• 发表时间: 2009-01-01
• 期刊: INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
• 影响因子: 2.6
• 作者: Al-Jahdari，Wael S.;Suzuki，Yoshiyuki;Nakano，Takashi
• 通讯作者: Nakano，Takashi

Monoamine-dependent, opioid-independent antihypersensitivity effects of intrathecally administered milnacipran, a serotonin noradrenaline reuptake inhibitor, in a postonerative pain model in rats.

鞘内注射米那普仑（一种血清素去甲肾上腺素再摄取抑制剂）在大鼠术后疼痛模型中的单胺依赖性、阿片类非依赖性抗过敏作用。

• 发表时间: 2010
• 期刊: J Pharmacol Exp Ther.
• 作者: 南野勝彦;名井陽;杉安謙仁朗;玉井宣行;橋本伸之;吉川秀樹;Obata H
• 通讯作者: Obata H