Study of Molecular Science with a Table-top Synchrotron

使用台式同步加速器进行分子科学研究

基本信息

批准号：
11304017
负责人：
TANABE Tetsumi
金额：
$ 24.81万
依托单位：
High energy Accelerator research Organization
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (A)
财政年份：
1999
资助国家：
日本
起止时间：
1999 至 2001
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-11304017/
关键词：
Storage ring Electrostatic ring Ultra-high vacuum Electrospray ion source Mass spectrometer Bio-molecularion Electron beam target Atomic collision 大気圧イオン源質量分析原子・分子

项目摘要

For atomic physics using cooler rings, the object of the present research is being directed to heavier molecular ions. One of the difficulties in studying low-charge and heavy molecular ions with the usual magnetic storage rings is in the increasing magnetic rigidity with ion mass. An electrostatic storage ring is more suitable to such ions because the electrostatic rigidly is independent of the ion mass. However, it was observed that the beam lifetime decreased greatly with increasing beam intensity for an existing electrostatic ring. In order to avoid such a difficulty, we constructed a new electrostatic synchrotron and showed that it can store atomic and molecular ions at sufficiently long lifetimes with moderate intensities. In order to study the feasibility of storing bio-molecular ions in the ring, for use in atomic-collision experiments, an electrospray ion (ES1) source was constructed For injecting ions into the storage ring, a high current pulse beam is required In order to st … More ack the beam, a linear RF trap was adopted The ion trap and the beam bunding system dramatically increased the pulse beam current. In order to mass-analyze bio-molecular ions from the ESI source, a mass spectrometer with a resolving power of about 4000 was constructed singly or multiply charged positive bio-molecular ions up to a mass of about 66, 000 including proteins were stored in the ring. Furthermore, a negative ion was also stored The beams have lifetimes of 12 s - 20 s, which are surprisingly long because large bio-molecules have usually been assumed to be fragile, resulting in a short surviving time in collisions with residual gas. An electron-beam target is indispensable for studying electron-ion collisions. An electron-beam target, which is also a compact electron cooler, has been designed. If we introduce an electron beam target into the ring, it will be possible to study electron-ion collision processes for bio-molecular ions. Thus, the ring is very attractive for studies in both biology and physics. Less

对于使用较冷环的原子物理学，当前研究的目标是针对较重的分子离子，用通常的磁存储环研究低电荷和重分子离子的困难之一在于随着离子质量的增加磁刚度。静电存储环更适合此类离子，因为静电严格地独立于离子质量。然而，据观察，现有静电环的束流寿命随着束流强度的增加而大大降低。我们构建了一个新的静电同步加速器并表明它可以以足够长的寿命和中等强度存储原子和分子离子。为了研究在环中存储生物分子离子用于原子碰撞实验的可行性，电喷雾离子（ES1）源。为了将离子注入存储环，需要高电流脉冲束为了使束流稳定，采用了线性射频陷阱离子陷阱和束束束缚系统显着增加为了对来自 ESI 源的生物分子离子进行质量分析，构建了分辨率约为 4000 的质谱仪，单电荷或多电荷正生物分子离子的质量高达约 66, 000。包括蛋白质在内的物质也储存在环中，此外，还储存了负离子。光束的寿命为 12 秒至 20 秒，这对于大生物分子来说是令人惊讶的长。通常认为电子束靶很脆弱，因此在与残余气体的碰撞中存活时间很短，对于研究电子-离子碰撞来说，电子束靶也是一种紧凑的电子冷却器。如果我们将电子束靶引入到环中，就可以研究生物分子离子的电子-离子碰撞过程，因此，该环对于生物学和物理学研究都非常有吸引力。