Relation between the molecular structure of functional monomers and their interaction on apatite surface

功能单体的分子结构及其在磷灰石表面相互作用的关系

• 批准号: 18592088
• 负责人: OGAWA Tatsuyuki
• 金额: $ 2.7万
• 依托单位: Okayama University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2006
• 资助国家: 日本
• 起止时间: 2006 至 2009
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-18592088/
• 关键词: 機能性モノマー; 4-MET; 10-MDP; Phenyl-P; アパタイト; 硬組織; NMR; XRD; XPS; 歯学; 接着

Although decayed/fractured teeth can be reconstructed minimally invasively and nearly invisibly using adhesive technology, the clinical longevity of dental composite restorations is still too short. Water sorption is thought to be the principal cause of destabilization of the biomaterial-tooth bond. However, the actual mechanisms of interfacial degradation are far from understood. In this study, the interaction of three monomers (4-MET/10-MDP/Phenyl-P) with hydroxyapatite (HAp), and for an experimental 10-MDP:EtOH:H_2O (15:45:40wt%) self-etch primer also with dentin/enamel, was characterized by XPS and XRD. The tensile bond strength (TBS) to enamel/dentin of the primer with and without 1wt% camphorquinone (CQ) added, was also measured. Regarding molecular interaction, the two extremes were Phenyl-P that rather "etched" and 10-MDP that rather "bonded" to HAp (with 4-MET behaving somewhat in between). XRD revealed a higher crystallite size/cristallinity for enamel, while nano-layering was more pronounced at dentin. The exp. primer needed CQ to obtain a TBS to dentin comparable to that of commercial material including 10-MDP, but not when bonded to enamel. It was indicated that adequate polymerization (by CQ) is needed to stabilize the formed nano-layer.

项目成果

Study on chemical interaction between 4-MET and hydroxyapatite using XPS.

利用 XPS 研究 4-MET 与羟基磷灰石之间的化学相互作用。

• 发表时间: 2006
• 期刊: Dental Materials Journal 25
• 作者: Nagakane;K.;Yoshida;Y.;Hirata;I.;Fukuda;R.;Nakayama;Y.;Shirai;K.;Ogawa;T.;Suzuki;K.;Van Meerbeek;B.;Okazaki;M.
• 通讯作者: M.

象牙質への接着～化学的接着の見地から. 日本歯科評論別冊/接着性コンポジットレジン修復の基礎と臨床(山田敏元編)

牙本质的附着力——从化学附着力的角度看日本牙科评论特刊/粘合复合树脂修复体的基础和临床实践（山田敏元编辑）

• 发表时间: 2007
• 作者: 吉田靖弘;鈴木一臣;宮崎真至
• 通讯作者: 宮崎真至

Development of a Self-Etch Adheseve for Resin-Modified Glass-Ionomers.

树脂改性玻璃离子聚合物自蚀刻粘合剂的开发。

• 发表时间: 2006
• 期刊: Journal of Dental Research 85
• 作者: Couinho;E.;Van Landuyt;K.;De Munck;J.;Poitevin;A.;Yoshida;Y.;Inoue;S.;Peumans;M.;Suzuki;K.;Lambrechts;P.;Van Meerbeek;B.
• 通讯作者: B.

Bonding effectiveness and interfacial characterization of a HEMA/TEGDMA-free three-step etch&rinse adhesive.

无 HEMA/TEGDMA 三步蚀刻的键合效果和界面表征

• 发表时间: 2008
• 期刊: Journal of Dentistry 36
• 作者: Mine;A.;De Munck;J.;Van Landuyt;K.L.;Poitevin;A.;Kuboki;T.;Yoshida;Y.;Suzuki;K.;Lambrechts;P.;Van Meerbeek;B.
• 通讯作者: B.

Origin of interfacial droplets with one-step self-etch adhesives

一步自蚀刻粘合剂界面液滴的起源

• 发表时间: 2007
• 期刊: Journal of Dental Research 86
• 作者: Van Landuyt;K.L.;Snauwaert;J.;De Munck;J.;Coutinho;E.;Poitevin;A.;Yoshida;Y.;Suzuzki;K.;Lambrechts;P.;Van Meerbeek. B.
• 通讯作者: Van Meerbeek. B.