The mechanism of Tissue Response in Orthodontic Tooth Movement

正畸牙移动的组织反应机制

• 批准号: 07407059
• 负责人: ISHIKAWA Hiroyuki
• 金额: $ 15.04万
• 依托单位: HOKKAIDO UNIVERSITY
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (A)
• 财政年份: 1995
• 资助国家: 日本
• 起止时间: 1995 至 1997
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-07407059/
• 关键词: Tooth Movement; Osteoc last; Degenerated Tissue; Periodontal Ligament; Stress Analysis; Elastic modulus; Tissue Response; Bone Resorption; 背部骨吸収; 血管分布; 荷重試験; Ni-Ti-合金; 超弾性; 組織変化; 応力分布; 有限要素法; 圧縮試験装置; ヤング率

The purpose of this study was to investigate the mechanism of tissue response in orthodontic tooth movement from histological observation, the analysis of stress distribution, and the analysis of tooth movement. The results obtained ware :1.Rear bone resorption seemed to depend on stress distribution and circulatory conditions in the perforating channels from bone marrow to periodontal space.2.The remaining bone and degenerated tissue in response to initial orthodontic force influenced stress distribution in the periodontal tissue due to the subsequent readjusted force.3.The specimen-specific finite element analysis showed that the osteoclast appearance and the formation of degenerated tissue are closely related to a specific level of the compressive stress in the periodontal ligament.4.The elasticity of the periodontal ligament was evaluated with a mechanical test machine developed. The elastic moduli of the periodontal ligament determined from the tensile and compressive tests under quasi-static conditions were 0.37(]SY.+-。[)0.11 and 0.079(]SY.+-。[)0.017MPa, respectively.5.The alveolar bone resorption rate was estimated from the clinical measurements of tooth movement and the finite eIement analysis. The rate to a unit stress was found to be 0.58(]SY.+-。[)0.16 mum/(kPa・day).

本研究的目的是通过组织学观察、应力分布分析和牙齿移动分析来探讨正畸牙齿移动时的组织反应机制。获得的结果是：1.后牙骨吸收似乎取决于应力分布。 2.初始正畸力响应下的剩余骨和退变组织，由于随后的重新调整，影响了牙周组织的应力分布。 3.针对标本的有限元分析表明，破骨细胞的出现和退变组织的形成与牙周膜中特定水平的压应力密切相关。4.用牙周膜的弹性来评估牙周膜的弹性。开发了机械试验机，通过准静态条件下的拉伸和压缩试验测定牙周膜的弹性模量为0.37(]SY.+-。分别为[)0.11和0.079(]SY.+-.[)0.017MPa。5.根据牙齿移动的临床测量和有限元分析估计牙槽骨吸收率。为 0.58(]SY.+-.[)0.16 妈妈/(kPa·天)。

项目成果

Seiki Yamanami: "Analysis of alveolar bone remodeling on orthodontics-Comparative study on alveolar bone resorption rate of moved teeth and fixed teeth-" Tecnical Report of IEICE. MBE-96. 19-24 (1996)

山波精树：《正畸学中牙槽骨重塑分析-移动牙与固定牙牙槽骨吸收率的比较研究-》IEICE技术报告。

Morimasa Nishihira: "Measurement of elastic properties of periodontal ligament." Tecnical Report of IEICE. MBE-96. 45-50 (1996)

Morimasa Nishihira：“牙周膜弹性特性的测量。”

Morimasa Nishihira: "Measurment of alastic modulus of periodontal ligament by tension and compression tests." Tecnical Report of IEICE. MBE-97. 75-80 (1997)

Morimasa Nishihira：“通过拉伸和压缩试验测量牙周膜的弹性模量。”

Katsuyuki Yamamoto: Springer-Verlag. Computational analysis of bone remodeling in orthodontics, Computational Biomechanics, ed.by k.Hayashi, 115-134 (1996)

山本胜之：施普林格出版社。

本村英示: "圧迫側歯根膜に生じる変性組織と応力分布との関連" 北海道歯学雑誌. 17・2. 312-324 (1996)

本村英二：“压缩牙周膜中产生的变性组织与应力分布的关系”北海道牙科杂志17・2（1996）。