Development of gravity-impervious, transportable chemical processes and creation of specialized reaction systems

开发不受重力影响的可运输化学过程并创建专门的反应系统

基本信息

批准号：
17360378
负责人：
MOROOKA Shigeharu
金额：
$ 8.38万
依托单位：
FUKUOKA UNIVERSITY
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (B)
财政年份：
2005
资助国家：
日本
起止时间：
2005 至 2006
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17360378/
关键词：
Micro and nano devices Fluid dynamics catalytic and chemical process Reaction and separation engineering Thermal engineering

项目摘要

1. An Archimedean microchannel was fabricated and used to separate solid particles from water. The spiral channel was held either horizontally or vertically, and slurries were introduced into the inner end of the microspiral. Solid particles moved along with the secondary flow (Dean vortex), and, at the same time, ascended to the lower walls due to the gravity. CFD simulation gave beneficial suggestions for designs of microspirals applicable to liquid/solid separation.2. A novel technique to measure the local thickness of a droplet or a liquid film was developed by using an interference fringe pattern that was formed by reflecting laser lights. The incremental height of the liquid layer was evaluated from the wavelength of the laser light and the refractive index of the liquid. This fringe method has great potential to obtain the three dimensional structure of liquid films which transform rapidly.3. A novel silicon/glass microfluidic device was developed, in which microchannel inner wa … More lls were modified to produce hydrophilic/hydrophobic surfaces selectively. This modification procedure made it possible to form a stable two-layer laminar flow interface between a flow of heavier water and lighter hexane, which were introduced into the upper and lower inlets, respectively.4. CdSe nanocrystals were prepared in a continuous-flow microtube reactor. Effects of reaction conditions on optical properties of the nanocrystals were investigated. The results showed that the micro flow reactor was beneficial for preparation of nanocrystals with narrow size distributions.5. a-Chymotrypsin was immobilized on the inner surface of a PTFE microtube by using glutalaldehyde and parahormaldehyde as cross linkers. The initial reaction rate in the microtubes increased with increasing enzyme concentration even when the substrate concentration was equivalent to the enzyme concentration, while those in the homogeneous batchwise reactor decreased in the range of higher enzyme concentrations.6. The above results were summarized to design gravity-impervious, transportable chemical processes which could be applied to production of specialty chemicals. Less

1. 制作阿基米德微通道，用于将固体颗粒与水分离。螺旋通道可水平或垂直固定，并将浆料引入微螺旋的内端，固体颗粒随二次流（迪安涡流）移动。，同时由于重力而上升到下壁，为适用于液/固分离的微螺旋设计提供了有益的建议。2．或者利用反射激光形成的干涉条纹图案来形成液体膜，根据激光的波长和液体的折射率来评估液体层的增量高度。这种条纹方法具有很大的潜力。 3.开发了一种新型硅/玻璃微流体装置，其中微通道内壁经过修饰以选择性地产生亲水/疏水表面。形式分别从上、下入口引入较重的水流和较轻的己烷流，形成稳定的双层层流界面。4．在连续流微管反应器中制备CdSe纳米晶体。4．研究结果表明，微流反应器有利于制备窄粒径分布的纳米晶。 5．即使当底物浓度与酶浓度相同时，微管中的初始反应速率也随着酶浓度的增加而增加，而均质间歇式反应器中的初始反应速率则随着酶浓度的增加而增加。 6. 对上述结果进行了总结，以设计可应用于特种化学品生产的不受重力影响的可运输化学工艺。

项目成果

期刊论文数量（0）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Phase Separation of Air Water Two-Phase Mixture Flowing in a Micro Channel

微通道内流动的气水两相混合物的相分离

DOI：
发表时间：
2005
期刊：
6^<th> KSME-JSME Thermal and Fluids Eng.Conf.
影响因子：
0
作者：
Y.Yamasaki;A.Kariyasaki;A.Ousaka;S.Morooka
通讯作者：
S.Morooka

Immobilization of α-chymotrypsin and determination of amount of enzyme and its activity in microtube reactors

微管反应器中α-胰凝乳蛋白酶的固定化及酶量及其活性的测定

DOI：
发表时间：
2006
期刊：
19th International Symposium on Chemical Engineering, Kyushu (Japan)-Daejeon/Chungnam (Korea)
影响因子：
0
作者：
Y.Machida;S.Morooka;Y.Yamasaki;M.Miyazaki;T.Honda;H.Maeda
通讯作者：
H.Maeda

Tubular Microreactor for Immobilized Enzyme Reaction

用于固定化酶反应的管式微反应器

DOI：
发表时间：
2005
期刊：
The 18^<th> Symposium on Chemical Engineering
影响因子：
0
作者：
Y.Machida;M.Miyazaki;T.Honda;H.Maeda;Y.Yamazaki;S.Morooka
通讯作者：
S.Morooka

Measurement of Liquid Film Thickness by a Fringe Method

DOI：
10.1080/01457630802290122
发表时间：
2009-01
期刊：
Heat Transfer Engineering
影响因子：
2.3
作者：
A. Kariyasaki;Y. Yamasaki;Masazumi Kagawa;T. Nagashima;A. Ousaka;S. Morooka
通讯作者：
A. Kariyasaki;Y. Yamasaki;Masazumi Kagawa;T. Nagashima;A. Ousaka;S. Morooka

Immobilization of a-chymotrypsin and determination of amount of enzyme and its activity in microtube reactors

微管反应器中α-胰凝乳蛋白酶的固定化及酶量及其活性的测定