Long-term prevention of oxidation of bioactive material using three-dimensional regeneration reaction of antioxidant with catechin

利用抗氧化剂与儿茶素的三维再生反应长期防止生物活性物质氧化

基本信息

批准号：
16360388
负责人：
YONEMOTO Toshikuni
金额：
$ 9.66万
依托单位：
Tohoku University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (B)
财政年份：
2004
资助国家：
日本
起止时间：
2004 至 2006
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-16360388/
关键词：
bioactive material prevention of oxidation antioxidant β-carotene vitaminE vitaminC catechin kinetic model 油水二相系 β-カロチン

项目摘要

In this research, a high-speed regeneration cycle of antioxidants was designed by combining an amphiphilic catechin with a lipophilic vitamin E and a hydrophilic vitamin C for the purpose of long-term prevention of f3-carotene oxidation in the food system. In the presence of vitamin E and C, the following things were clarified: 1) the carotene oxidation was prevented as long as vitamin E existed in the system, 2) vitamin C was related to two contrastive reactions consuming and regenerating vitamin E, 3) the prevention period of carotene oxidation significantly increased under specific conditions. Conventionally the regeneration reaction of vitamin E by vitamin C was considered to contribute the increase of the prevention period. However, oxygen in the system was clarified to be almost consumed by the oxidation of vitamin C itself and consequently the carotene oxidation was prevented. The novel kinetic model considering the reaction mechanisms of carotene, vitamin E and C well described the contrastive effects progressing or preventing the carotene oxidation according to the amounts of vitamin C and oxygen in the system. On the other hand, the following things were clarified in the presence of catechin: 1) catechin was related to two contrastive reactions consuming carotene and preventing the carotene oxidation and 2) the structure of catechin was controlled which reaction preferentially occurred.

在这项研究中，通过将两亲性儿茶素与亲脂性维生素E和亲水性维生素C相结合，以长期预防食品系统中的F3-碳烯氧化，从而设计了抗氧化剂的高速再生周期。在存在维生素E和C的情况下，阐明了以下内容：1）只要系统中存在维生素E，就可以防止胡萝卜素氧化，2）维生素C与在特定条件下的服用烯氧化的预防显着增加了，维生素C与消耗和再生维生素E的两种对比反应有关。从传统上讲，维生素C对维生素E的再生反应被认为有助于预防时期的增加。然而，系统中的氧气几乎被维生素C本身的氧化所消耗，因此阻止了胡萝卜素氧化。考虑胡萝卜素，维生素E和C的反应机理的新型动力学模型很好地描述了对比度效应或根据系统中维生素C和氧的量进行的对比度效应或预防胡萝卜素氧化。另一方面，在存在儿茶素的情况下阐明了以下内容：1）儿茶素与两种消耗胡萝卜素的对比反应有关，并防止胡萝卜素氧化和2）控制结构的结构，该结构是优先发生的反应。